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ID

45595

Beschreibung

Principal Investigator: Louis Fiore, MD, VA Boston Healthcare System, Boston, MA, USA MeSH: Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001374 The Research for Precision Oncology Program (RePOP) is a research activity that establishes a cohort of Veterans diagnosed with cancer and who have had genomic analyses performed on their tumor tissue as part of standard of care. All data relevant to a patient's cancer and cancer care will be collected under RePOP, including patient demographics, co-morbidities, genomic analysis, treatments, medications, lab values, imaging studies, and outcomes. All RePOP participants will have signed/verbal informed consent and signed HIPAA authorization to have their data stored and shared from RePOP's Precision Oncology Program Data Repository (PODR). The Applied Proteogenomics OrganizationaL Learning and Outcomes (APOLLO) network is a collaboration between NCI, the Department of Defense (DoD), and the Department of Veterans Affairs (VA) to incorporate proteogenomics into patient care as a way of looking beyond the genome, to the activity and expression of the proteins that the genome encodes. The emerging field of proteogenomics aims to better predict how patients will respond to therapy by screening their tumors for both genetic abnormalities and protein information, an approach that has been made possible in recent years due to advances in proteomic technology.

Link

dbGaP study = phs001374

Stichworte

  1. 07.02.23 07.02.23 - Simon Heim
Rechteinhaber

Louis Fiore, MD, VA Boston Healthcare System, Boston, MA, USA

Hochgeladen am

7. Februar 2023

DOI

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Lizenz

Creative Commons BY 4.0

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    dbGaP phs001374 VA APOLLO Project - Research for Precision Oncology (RePOP)

    Eligibility Criteria

    Inclusion and exclusion criteria
    Beschreibung

    Inclusion and exclusion criteria

    Alias
    UMLS CUI [1,1]
    C1512693 (Inclusion)
    UMLS CUI [1,2]
    C0680251 (Exclusion Criteria)
    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.
    Beschreibung

    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.

    Datentyp

    boolean

    Alias
    UMLS CUI [1,1]
    C1548635 (Eligible)
    UMLS CUI [1,2]
    C0035168 (research)
    UMLS CUI [1,3]
    C1706245 (Precision - characteristic)
    UMLS CUI [1,4]
    C0027651 (Neoplasms)
    SNOMED
    108369006
    UMLS CUI [1,5]
    C0920688 (Cancer Diagnosis)
    UMLS CUI [1,6]
    C0521093 (Confirmed by)
    SNOMED
    59156000
    UMLS CUI [1,7]
    C0030664 (Pathology)
    SNOMED
    394595002
    UMLS CUI [1,8]
    C0184603 (Physician status report)
    SNOMED
    385779005
    UMLS CUI [1,9]
    C0025102 (Medical Records)
    SNOMED
    129465004
    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care
    Beschreibung

    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care

    Datentyp

    boolean

    Alias
    UMLS CUI [1,1]
    C0012878 (DNA Mutational Analysis)
    UMLS CUI [1,2]
    C0006826 (Malignant Neoplasms)
    SNOMED
    363346000
    LOINC
    LP100805-3
    UMLS CUI [1,3]
    C0178913 (Blood specimen)
    SNOMED
    119297000
    UMLS CUI [1,4]
    C0205210 (Clinical)
    SNOMED
    58147004
    UMLS CUI [1,5]
    C0205547 (Routine)
    SNOMED
    50811001
    LOINC
    LA9035-2
    Be at least 18 years of age
    Beschreibung

    Be at least 18 years of age

    Datentyp

    boolean

    Alias
    UMLS CUI [1,1]
    C0001779 (Age)
    SNOMED
    424144002
    LOINC
    LP28815-6
    Plan to continue to seek care at the VA
    Beschreibung

    Plan to continue to seek care at the VA

    Datentyp

    boolean

    Alias
    UMLS CUI [1,1]
    C0032074 (Cognitive function: planning)
    SNOMED
    312011006
    UMLS CUI [1,2]
    C0599788 (care seeking)
    Be competent to provide informed consent
    Beschreibung

    Be competent to provide informed consent

    Datentyp

    boolean

    Alias
    UMLS CUI [1,1]
    C0086035 (Competence)
    SNOMED
    32082000
    UMLS CUI [1,2]
    C1999230 (Providing (action))
    UMLS CUI [1,3]
    C0021430 (Informed Consent)

    Ähnliche Modelle

    Eligibility Criteria

    Name
    Typ
    Description | Question | Decode (Coded Value)
    Datentyp
    Alias
    Item Group
    Inclusion and exclusion criteria
    C1512693 (UMLS CUI [1,1])
    C0680251 (UMLS CUI [1,2])
    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.
    Item
    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.
    boolean
    C1548635 (UMLS CUI [1,1])
    C0035168 (UMLS CUI [1,2])
    C1706245 (UMLS CUI [1,3])
    C0027651 (UMLS CUI [1,4])
    C0920688 (UMLS CUI [1,5])
    C0521093 (UMLS CUI [1,6])
    C0030664 (UMLS CUI [1,7])
    C0184603 (UMLS CUI [1,8])
    C0025102 (UMLS CUI [1,9])
    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care
    Item
    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care
    boolean
    C0012878 (UMLS CUI [1,1])
    C0006826 (UMLS CUI [1,2])
    C0178913 (UMLS CUI [1,3])
    C0205210 (UMLS CUI [1,4])
    C0205547 (UMLS CUI [1,5])
    Be at least 18 years of age
    Item
    Be at least 18 years of age
    boolean
    C0001779 (UMLS CUI [1,1])
    Plan to continue to seek care at the VA
    Item
    Plan to continue to seek care at the VA
    boolean
    C0032074 (UMLS CUI [1,1])
    C0599788 (UMLS CUI [1,2])
    Be competent to provide informed consent
    Item
    Be competent to provide informed consent
    boolean
    C0086035 (UMLS CUI [1,1])
    C1999230 (UMLS CUI [1,2])
    C0021430 (UMLS CUI [1,3])

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