ID

45575

Description

Principal Investigator: Mark Silverberg, MD., PhD, Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, CANADA MeSH: Inflammatory Bowel Diseases,Crohn Disease,Colitis, Ulcerative,Pouchitis,Adenomatous Polyposis Coli https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000659 This study involved evaluation of the tissue associated microbiome of the ileal pouch following surgery for ulcerative colitis (UC) or familial adenomatous polyposis (FAP). Individuals were recruited, with biopsies taken from the ileal pouch and the pre-pouch ileum, microbial DNA was extracted and sequenced using 454 pyrosequencing. Total bacterial community structure and abundance were evaluated to determine which changes were characteristic of inflammatory phenotypes including pouchitis (inflammation of the ileal pouch) and a Crohn's disease-like phenotype.

Link

dbGaP study = phs000659

Keywords

  1. 1/24/23 1/24/23 - Simon Heim
Copyright Holder

Mark Silverberg, MD., PhD, Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, CANADA

Uploaded on

January 24, 2023

DOI

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License

Creative Commons BY 4.0

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dbGaP phs000659 Mount Sinai Hospital (MSH, Toronto, CANADA) pelvic pouch microbiome study

Sample - Attribute Information

pht003524
Description

pht003524

Alias
UMLS CUI [1,1]
C3846158
De-identified Sample ID
Description

#SampleID

Data type

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C1299222
Body site where sample was collected
Description

BODY_SITE

Data type

string

Alias
UMLS CUI [1,1]
C0449705
Analyte Type
Description

ANALYTE_TYPE

Data type

string

Alias
UMLS CUI [1,1]
C4744818
Tumor status
Description

IS_TUMOR

Data type

string

Alias
UMLS CUI [1,1]
C0475752
Name of the center which conducted sequencing
Description

SEQUENCING_CENTER

Data type

string

Alias
UMLS CUI [1,1]
C5575037
UMLS CUI [1,2]
C0027365
UMLS CUI [1,3]
C1561491

Similar models

Sample - Attribute Information

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht003524
C3846158 (UMLS CUI [1,1])
#SampleID
Item
De-identified Sample ID
string
C4684638 (UMLS CUI [1,1])
C1299222 (UMLS CUI [1,2])
BODY_SITE
Item
Body site where sample was collected
string
C0449705 (UMLS CUI [1,1])
ANALYTE_TYPE
Item
Analyte Type
string
C4744818 (UMLS CUI [1,1])
IS_TUMOR
Item
Tumor status
string
C0475752 (UMLS CUI [1,1])
SEQUENCING_CENTER
Item
Name of the center which conducted sequencing
string
C5575037 (UMLS CUI [1,1])
C0027365 (UMLS CUI [1,2])
C1561491 (UMLS CUI [1,3])

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