ID
45535
Beschreibung
Principal Investigator: Kendall Van Keuren-Jensen, PhD, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA MeSH: Alzheimer Disease,Parkinson Disease https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000727 We profiled the miRNA contents from cerebrospinal fluid and serum (using next generation sequencing) from postmortem patients diagnosed with Alzheimer's or Parkinson's disease, and neurologically normal controls. All biofluids were cell-free and patient matched, there was one cerebrospinal fluid and one serum sample from each of 70 patients with Alzheimer's disease, 67 patients with Parkinson's disease and 78 age-similar controls. We correlated the miRNA changes with measurements of neuropathology such as plaques, tangles and Lewy bodies.
Link
Stichworte
Versionen (1)
- 28.12.22 28.12.22 - Chiara Middel
Rechteinhaber
Kendall Van Keuren-Jensen, PhD, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA
Hochgeladen am
28. Dezember 2022
DOI
Für eine Beantragung loggen Sie sich ein.
Lizenz
Creative Commons BY 4.0
Modell Kommentare :
Hier können Sie das Modell kommentieren. Über die Sprechblasen an den Itemgruppen und Items können Sie diese spezifisch kommentieren.
Itemgroup Kommentare für :
Item Kommentare für :
Um Formulare herunterzuladen müssen Sie angemeldet sein. Bitte loggen Sie sich ein oder registrieren Sie sich kostenlos.
dbGaP phs000727 miRNA profiles in serum and CSF of Parkinson's and Alzheimer's patients
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent - Affection Status Information
- Subject - Sample Mapping
- The dataset provides information about disease duration, presence of APOE alleles, time interval between death and tissue harvest, location and extend of plaque and tangle formation, degree of Substantia Nigra depigmentation and status of Lewy body formation observed, Braak/NIA-Reagan scores and general sociodemographic information.
- Sample Attribute Information
Ähnliche Modelle
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent - Affection Status Information
- Subject - Sample Mapping
- The dataset provides information about disease duration, presence of APOE alleles, time interval between death and tissue harvest, location and extend of plaque and tangle formation, degree of Substantia Nigra depigmentation and status of Lewy body formation observed, Braak/NIA-Reagan scores and general sociodemographic information.
- Sample Attribute Information
C0680251 (UMLS CUI [1,2])
C0030567 (UMLS CUI [1,2])
C0002395 (UMLS CUI [1,3])
C0332145 (UMLS CUI [1,4])
C0876934 (UMLS CUI [1,5])
C0679228 (UMLS CUI [1,6])
C0027853 (UMLS CUI [2,1])
C0205307 (UMLS CUI [2,2])