ID

45518

Description

Principal Investigator: Steven Treon, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, USA MeSH: Waldenstrom Macroglobulinemia https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000740 Whole genome sequencing was conducted on 10 tumor/germline paired samples along with 20 additional unpaired tumor samples from patients with Waldesntrom's macroglobulinemia. Tumor lymphoplasmacytic lymphoma cells were obtained from CD19+ selected bone marrow mononuclear cells. Germline tissue was obtained from CD19 depleted peripheral blood mononuclear cells. High molecular weight DNA was then submitted for whole genome sequencing with Complete Genomics and aligned to HG19/NCBI human reference build 37.

Link

dbGaP-study=phs000740

Keywords

  1. 12/14/22 12/14/22 - Chiara Middel
Copyright Holder

Steven Treon, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, USA

Uploaded on

December 14, 2022

DOI

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License

Creative Commons BY 4.0

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dbGaP phs000740 Whole Genome Sequencing of Waldenstrom's Macroglobulinemia

Eligibility Criteria

Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
All participants had to have given consent to sample collection in accordance with the Dana-Farber Cancer Institute Institutional Review Board and received a clinicopathological diagnosis of WM as defined by the Second International Workshop on WM.
Description

Elig.phs000740.v1.p1.1

Data type

boolean

Alias
UMLS CUI [1,1]
C0021430
UMLS CUI [1,2]
C0200345
UMLS CUI [1,3]
C0205210
UMLS CUI [1,4]
C0205469
UMLS CUI [1,5]
C0011900
UMLS CUI [1,6]
C0024419
UMLS CUI [1,7]
C0679228

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000740.v1.p1.1
Item
All participants had to have given consent to sample collection in accordance with the Dana-Farber Cancer Institute Institutional Review Board and received a clinicopathological diagnosis of WM as defined by the Second International Workshop on WM.
boolean
C0021430 (UMLS CUI [1,1])
C0200345 (UMLS CUI [1,2])
C0205210 (UMLS CUI [1,3])
C0205469 (UMLS CUI [1,4])
C0011900 (UMLS CUI [1,5])
C0024419 (UMLS CUI [1,6])
C0679228 (UMLS CUI [1,7])

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