0 Evaluaciones

ID

45514

Descripción

Principal Investigator: Susan K. Dutcher, PhD, Washington University School of Medicine, St. Louis, MO, USA MeSH: Lung Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000728 Over 85% of all patients diagnosed with lung cancer report a history of tobacco use, though only 10% of tobacco smokers eventually develop lung cancer. Epidemiologic studies have shown that family members of patients with lung cancer have a higher risk of developing lung cancer than controls. In an effort to identify variants associated with tobacco induced lung cancer, we have sequenced germline DNA from affected and unaffected members of families with strong histories of tobacco related lung cancer.

Link

dbGaP study = phs000728

Palabras clave

  1. 13/12/22 13/12/22 - Simon Heim
Titular de derechos de autor

Susan K. Dutcher, PhD, Washington University School of Medicine, St. Louis, MO, USA

Subido en

13 de diciembre de 2022

DOI

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Licencia

Creative Commons BY 4.0

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    dbGaP phs000728 Lung Cancer Susceptibility in Smokers

    Sample ID, analyte type, tissue type of sample, and tumor status of sample obtained from participants with or without lung cancer and involved in the "The Genetics of Lung Cancer Susceptibility in Smokers" project.

    pht003768
    Descripción

    pht003768

    Alias
    UMLS CUI [1,1]
    C3846158 (Other Coding)
    LOINC
    LA4728-7
    De-identified sample name
    Descripción

    SAMPID

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C4684638 (De-identified Information)
    UMLS CUI [1,2]
    C1299222 (Sample identification number)
    SNOMED
    372274003
    DNA or RNA
    Descripción

    ANALYTE_TYPE

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C0012854 (DNA)
    SNOMED
    24851008
    LOINC
    LP32416-7
    UMLS CUI [1,2]
    C0035668 (RNA)
    SNOMED
    27888000
    LOINC
    LP32423-3
    Substance from which analyte was extracted
    Descripción

    TISSUE_TYPE

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C0439861 (Substance)
    SNOMED
    105590001
    LOINC
    LP20778-4
    UMLS CUI [1,2]
    C0443354 (Analyte)
    SNOMED
    272524002
    UMLS CUI [1,3]
    C0185115 (Extraction)
    SNOMED
    129415008
    Is the sample a tumor sample
    Descripción

    IS_TUMOR

    Tipo de datos

    string

    Alias
    UMLS CUI [1,1]
    C0475358 (Tumor tissue sample)
    SNOMED
    258435002

    Similar models

    Sample ID, analyte type, tissue type of sample, and tumor status of sample obtained from participants with or without lung cancer and involved in the "The Genetics of Lung Cancer Susceptibility in Smokers" project.

    Name
    Tipo
    Description | Question | Decode (Coded Value)
    Tipo de datos
    Alias
    Item Group
    pht003768
    C3846158 (UMLS CUI [1,1])
    SAMPID
    Item
    De-identified sample name
    string
    C4684638 (UMLS CUI [1,1])
    C1299222 (UMLS CUI [1,2])
    ANALYTE_TYPE
    Item
    DNA or RNA
    string
    C0012854 (UMLS CUI [1,1])
    C0035668 (UMLS CUI [1,2])
    TISSUE_TYPE
    Item
    Substance from which analyte was extracted
    string
    C0439861 (UMLS CUI [1,1])
    C0443354 (UMLS CUI [1,2])
    C0185115 (UMLS CUI [1,3])
    IS_TUMOR
    Item
    Is the sample a tumor sample
    string
    C0475358 (UMLS CUI [1,1])

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