ID

45453

Descripción

Principal Investigator: Winnie Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA MeSH: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000745 In this study, RNA sequencing was performed on astrocytes microdissected from the posterior cingulate cortex of Alzheimer's disease subjects and healthy elderly controls.

Link

dbGaP-study=phs000745

Palabras clave

  1. 11/12/22 11/12/22 - Chiara Middel
Titular de derechos de autor

Winnie Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA

Subido en

11 de diciembre de 2022

DOI

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Licencia

Creative Commons BY 4.0

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dbGaP phs000745 RNAseq analysis of posterior cingulate astrocytes in Alzheimer's disease

Eligibility Criteria

Inclusion and exclusion criteria
Descripción

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
Alzheimer's subjects had expired ages > 65, frequent plaque densities, Braak scores of at least IV, and intermediate to high criteria met for NIA-R.
Descripción

Elig.phs000745.v1.p1.1

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1698493
UMLS CUI [1,2]
C0002395
UMLS CUI [1,3]
C0001779
UMLS CUI [1,4]
C0332461
UMLS CUI [1,5]
C0178587
UMLS CUI [1,6]
C0449394
UMLS CUI [1,7]
C0205250
UMLS CUI [1,8]
C0449820
UMLS CUI [1,9]
C0679228
UMLS CUI [1,10]
C0205250
UMLS CUI [1,11]
C0205103
Healthy elderly controls had expired ages of > 65, zero to moderate plaque densities, Braak scores less than or equal to IV, and no criteria met for NIA-R.
Descripción

Elig.phs000745.v1.p1.2

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C2986479
UMLS CUI [1,2]
C0001779
UMLS CUI [1,3]
C0332461
UMLS CUI [1,4]
C0178587
UMLS CUI [1,5]
C0449394
UMLS CUI [1,6]
C0449820
UMLS CUI [1,7]
C0679228

Similar models

Eligibility Criteria

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000745.v1.p1.1
Item
Alzheimer's subjects had expired ages > 65, frequent plaque densities, Braak scores of at least IV, and intermediate to high criteria met for NIA-R.
boolean
C1698493 (UMLS CUI [1,1])
C0002395 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
C0332461 (UMLS CUI [1,4])
C0178587 (UMLS CUI [1,5])
C0449394 (UMLS CUI [1,6])
C0205250 (UMLS CUI [1,7])
C0449820 (UMLS CUI [1,8])
C0679228 (UMLS CUI [1,9])
C0205250 (UMLS CUI [1,10])
C0205103 (UMLS CUI [1,11])
Elig.phs000745.v1.p1.2
Item
Healthy elderly controls had expired ages of > 65, zero to moderate plaque densities, Braak scores less than or equal to IV, and no criteria met for NIA-R.
boolean
C2986479 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C0332461 (UMLS CUI [1,3])
C0178587 (UMLS CUI [1,4])
C0449394 (UMLS CUI [1,5])
C0449820 (UMLS CUI [1,6])
C0679228 (UMLS CUI [1,7])

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