ID

45444

Beschrijving

Principal Investigator: Scott Boyd, MD, PhD, Stanford University, Palo Alto, CA, USA MeSH: Influenza Vaccines https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000760 The data consist of the DNA sequences of antibody gene rearrangements from peripheral blood human B cells of subjects vaccinated with trivalent seasonal influenza or monovalent pandemic H1N1 vaccine. Multiple replicate libraries of immunoglobulin heavy chain gene rearrangements were prepared from each subject for each time point.

Link

dbGaP-study=phs000760

Trefwoorden

  1. 07-12-22 07-12-22 - Chiara Middel
Houder van rechten

Scott Boyd, MD, PhD, Stanford University, Palo Alto, CA, USA

Geüploaded op

7 december 2022

DOI

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Licentie

Creative Commons BY 4.0

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dbGaP phs000760 Human Responses to Influenza Vaccination

Eligibility Criteria

Inclusion and exclusion criteria
Beschrijving

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
The seven healthy vaccine seroconverter subjects and seven healthy non-seroconverter subjects in the study were recruited at Duke University and were given TIV (Sanofi Pasteur, Swiftwater PA): 2007-2008 Fluzone® vaccine or 2008-2009 Fluzone® vaccine. Blood samples were collected prior to vaccination and on days seven and twenty-one after vaccination. Subject BFI-278 recruited at Stanford University was administered Influenza A (H1N1) 2009 monovalent inactivated vaccination in January 2010. Blood was collected immediately prior to vaccination and on days four to fourteen after vaccination. Ten months after receiving the monovalent H1N1 vaccine, BFI-278 was administered a seasonal trivalent inactivated vaccine that included the Influenza A/California/07/2009-like pandemic H1N1 antigenic component. Blood was drawn from BFI-278 prior to 2010 TIV vaccination, and at days seven and twenty-one post-vaccination.
Beschrijving

Elig.phs000760.v1.p1.1

Datatype

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0042196
UMLS CUI [1,3]
C4042908
UMLS CUI [2,1]
C1512693
UMLS CUI [2,2]
C0042196
UMLS CUI [2,3]
C1298908
UMLS CUI [2,4]
C4042908
UMLS CUI [3,1]
C1277698
UMLS CUI [3,2]
C0011008
UMLS CUI [3,3]
C0332152
UMLS CUI [3,4]
C0042196
UMLS CUI [3,5]
C3842672
UMLS CUI [3,6]
C4082109
UMLS CUI [4,1]
C0681850
UMLS CUI [4,2]
C0242800
UMLS CUI [4,3]
C0205394
UMLS CUI [4,4]
C0019994
UMLS CUI [4,5]
C1277698
UMLS CUI [4,6]
C0011008
UMLS CUI [4,7]
C0332152
UMLS CUI [4,8]
C0042196
UMLS CUI [4,9]
C3840892
UMLS CUI [4,10]
C4082118
UMLS CUI [5,1]
C0681850
UMLS CUI [5,2]
C0242800
UMLS CUI [5,3]
C0205394
UMLS CUI [5,4]
C0019994
UMLS CUI [5,5]
C1524062
UMLS CUI [5,6]
C0042196
UMLS CUI [5,7]
C1277698
UMLS CUI [5,8]
C0011008
UMLS CUI [5,9]
C0332152
UMLS CUI [5,10]
C0042196
UMLS CUI [5,11]
C3842672
UMLS CUI [5,12]
C4082109

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000760.v1.p1.1
Item
The seven healthy vaccine seroconverter subjects and seven healthy non-seroconverter subjects in the study were recruited at Duke University and were given TIV (Sanofi Pasteur, Swiftwater PA): 2007-2008 Fluzone® vaccine or 2008-2009 Fluzone® vaccine. Blood samples were collected prior to vaccination and on days seven and twenty-one after vaccination. Subject BFI-278 recruited at Stanford University was administered Influenza A (H1N1) 2009 monovalent inactivated vaccination in January 2010. Blood was collected immediately prior to vaccination and on days four to fourteen after vaccination. Ten months after receiving the monovalent H1N1 vaccine, BFI-278 was administered a seasonal trivalent inactivated vaccine that included the Influenza A/California/07/2009-like pandemic H1N1 antigenic component. Blood was drawn from BFI-278 prior to 2010 TIV vaccination, and at days seven and twenty-one post-vaccination.
boolean
C1512693 (UMLS CUI [1,1])
C0042196 (UMLS CUI [1,2])
C4042908 (UMLS CUI [1,3])
C1512693 (UMLS CUI [2,1])
C0042196 (UMLS CUI [2,2])
C1298908 (UMLS CUI [2,3])
C4042908 (UMLS CUI [2,4])
C1277698 (UMLS CUI [3,1])
C0011008 (UMLS CUI [3,2])
C0332152 (UMLS CUI [3,3])
C0042196 (UMLS CUI [3,4])
C3842672 (UMLS CUI [3,5])
C4082109 (UMLS CUI [3,6])
C0681850 (UMLS CUI [4,1])
C0242800 (UMLS CUI [4,2])
C0205394 (UMLS CUI [4,3])
C0019994 (UMLS CUI [4,4])
C1277698 (UMLS CUI [4,5])
C0011008 (UMLS CUI [4,6])
C0332152 (UMLS CUI [4,7])
C0042196 (UMLS CUI [4,8])
C3840892 (UMLS CUI [4,9])
C4082118 (UMLS CUI [4,10])
C0681850 (UMLS CUI [5,1])
C0242800 (UMLS CUI [5,2])
C0205394 (UMLS CUI [5,3])
C0019994 (UMLS CUI [5,4])
C1524062 (UMLS CUI [5,5])
C0042196 (UMLS CUI [5,6])
C1277698 (UMLS CUI [5,7])
C0011008 (UMLS CUI [5,8])
C0332152 (UMLS CUI [5,9])
C0042196 (UMLS CUI [5,10])
C3842672 (UMLS CUI [5,11])
C4082109 (UMLS CUI [5,12])

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