ID

45437

Description

Principal Investigator: William G. Iacono, PhD, University of Minnesota, Minneapolis, MN, USA MeSH: Substance-Related Disorders,Impulse Control Disorders https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000620 This is an epidemiological study of substance abuse and related psychopathology in which the subjects have been drawn from the Minnesota Center for Twin and Family Research (MCTFR). The MCTFR is a large, ongoing, family-based study. It is in part a longitudinal study of two cohorts of adolescent twins and their parents. It additionally includes a parallel longitudinal study of adolescent adoptive siblings, biologically related siblings, and their parents. Over 1500 twin families and 350 adoptive and biological sibling families have been studied, with follow-up assessments occurring approximately every 3 years. The MCTFR gathered detailed, standardized data on study participants including DSM-IIIR and DSM-IV diagnostic interview and questionnaire data. For the Genome-Wide Association Study of Behavioral Disinhibition, parental intake data plus that adolescent data gathered closest to the children 17th birthday (between ages 16.5 and 21) was used.

Link

dbGaP-study=phs000620

Keywords

Versions (1)
  1. 11/29/22 11/29/22 - Chiara Middel
Copyright Holder

William G. Iacono, PhD, University of Minnesota, Minneapolis, MN, USA

Uploaded on

November 29, 2022

DOI

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License

Creative Commons BY 4.0
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dbGaP phs000620 Minnesota Center for Twin and Family Research (MCTFR)

English

Eligibility Criteria

7 forms  
Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
The MCTFR twin-family sample was ascertained through Minnesota birth records. The adoptive-family sample was ascertained from infant placements made by the three largest private adoption agencies in Minnesota. The non-adoptive controls were ascertained through Minnesota state birth records and selected to have a pair of siblings of comparable age and gender to the adoptive sibling pairs. Eligibility requirements for the adoptive families included having, at the time of the intake assessment, an adopted adolescent between the ages of 11 and 21 who had been placed permanently in the adoptive home prior to the age of 2 years and a second adolescent in the home who was not biologically related to the adopted adolescent and who was no more than 5 years different in age. The second child could be biologically related to one or both of the parents or could, like the first child, have been adopted and placed prior to the age of 2 years. Additional eligibility requirements, which applied to all subjects, included living within a day drive of the University of Minnesota laboratory and not having any physical or mental disability that would preclude completing the day-long, in-person intake assessment. To be included in this analysis, the subject must additionally have been willing to make a blood or saliva donation.
Description

Elig.phs000620.v1.p1.1

Data type

boolean

Alias
UMLS CUI [1,1]
C0041427
UMLS CUI [1,2]
C0015576
UMLS CUI [1,3]
C1698493
UMLS CUI [1,4]
C0005609
UMLS CUI [2,1]
C0682319
UMLS CUI [2,2]
C1698493
UMLS CUI [2,3]
C0021270
UMLS CUI [2,4]
C1524072
UMLS CUI [3,1]
C1698493
UMLS CUI [3,2]
C0009932
UMLS CUI [3,3]
C0681880
UMLS CUI [3,4]
C0001779
UMLS CUI [3,5]
C0079399
UMLS CUI [4,1]
C1512693
UMLS CUI [4,2]
C0682319
UMLS CUI [4,3]
C0205653
UMLS CUI [4,4]
C0337541
UMLS CUI [4,5]
C0205436
UMLS CUI [4,6]
C0205653
UMLS CUI [4,7]
C0337541
UMLS CUI [4,8]
C4331838
UMLS CUI [5,1]
C1512693
UMLS CUI [5,2]
C0017446
UMLS CUI [5,3]
C1298908
UMLS CUI [5,4]
C0520817
UMLS CUI [5,5]
C1306341
UMLS CUI [6,1]
C1512693
UMLS CUI [6,2]
C0600109
UMLS CUI [6,3]
C0005794
UMLS CUI [6,4]
C0036087
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Similar models

Eligibility Criteria

7 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000620.v1.p1.1
Item
The MCTFR twin-family sample was ascertained through Minnesota birth records. The adoptive-family sample was ascertained from infant placements made by the three largest private adoption agencies in Minnesota. The non-adoptive controls were ascertained through Minnesota state birth records and selected to have a pair of siblings of comparable age and gender to the adoptive sibling pairs. Eligibility requirements for the adoptive families included having, at the time of the intake assessment, an adopted adolescent between the ages of 11 and 21 who had been placed permanently in the adoptive home prior to the age of 2 years and a second adolescent in the home who was not biologically related to the adopted adolescent and who was no more than 5 years different in age. The second child could be biologically related to one or both of the parents or could, like the first child, have been adopted and placed prior to the age of 2 years. Additional eligibility requirements, which applied to all subjects, included living within a day drive of the University of Minnesota laboratory and not having any physical or mental disability that would preclude completing the day-long, in-person intake assessment. To be included in this analysis, the subject must additionally have been willing to make a blood or saliva donation.
boolean
C0041427 (UMLS CUI [1,1])
C0015576 (UMLS CUI [1,2])
C1698493 (UMLS CUI [1,3])
C0005609 (UMLS CUI [1,4])
C0682319 (UMLS CUI [2,1])
C1698493 (UMLS CUI [2,2])
C0021270 (UMLS CUI [2,3])
C1524072 (UMLS CUI [2,4])
C1698493 (UMLS CUI [3,1])
C0009932 (UMLS CUI [3,2])
C0681880 (UMLS CUI [3,3])
C0001779 (UMLS CUI [3,4])
C0079399 (UMLS CUI [3,5])
C1512693 (UMLS CUI [4,1])
C0682319 (UMLS CUI [4,2])
C0205653 (UMLS CUI [4,3])
C0337541 (UMLS CUI [4,4])
C0205436 (UMLS CUI [4,5])
C0205653 (UMLS CUI [4,6])
C0337541 (UMLS CUI [4,7])
C4331838 (UMLS CUI [4,8])
C1512693 (UMLS CUI [5,1])
C0017446 (UMLS CUI [5,2])
C1298908 (UMLS CUI [5,3])
C0520817 (UMLS CUI [5,4])
C1306341 (UMLS CUI [5,5])
C1512693 (UMLS CUI [6,1])
C0600109 (UMLS CUI [6,2])
C0005794 (UMLS CUI [6,3])
C0036087 (UMLS CUI [6,4])
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