ID

45432

Descripción

Principal Investigator: Ann G. Schwartz, PhD, MPH, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA MeSH: Lung Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000629 Familial lung cancer cases were collected by the Genetic Epidemiology of Lung Cancer Consortium (GELCC) recruitment sites: University of Cincinnati, Karmanos Cancer Institute at Wayne State University, Louisiana State University Health Sciences Center-New Orleans, Mayo Clinic, and Medical College of Ohio. Familial cases for this study came from three sources: 1) one case each from families (at least 3 affected lung cancer cases in the family) included in the linkage analysis; 2) one case from linkage-eligible families (at least 3 affected lung cancer cases in the family) but where there were insufficient biospecimens available to make them informative for linkage analysis; and 3) one case from families not eligible for the linkage study with a family history of at least one first or second degree relative affected with lung cancer. Unrelated controls were selected from 1) among the spouses of family members, thus matching on socio-economic status (SES) and ethnicity (typically) of the cases or 2) from case-control studies of lung cancer conducted in the same location in which the linkage families were collected and matched on age, sex, and race. All cases and controls self-reported as European American. Biospecimens used for normal DNA extraction included blood, saliva or mouthwash. Some samples underwent whole genome amplication.

Link

dbGaP-study=phs000629

Palabras clave

  1. 29/11/22 29/11/22 - Chiara Middel
Titular de derechos de autor

Ann G. Schwartz, PhD, MPH, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA

Subido en

29 de noviembre de 2022

DOI

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Licencia

Creative Commons BY 4.0

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dbGaP phs000629 GWAS of Familial Lung Cancer

Subject ID, case or control status, age, race, sex, smoking history, and number of cigarette packs per year of participants affected or not affected with familial lung cancer and involved in the "Genetic Epidemiology of Lung Cancer Consortium GWAS of Familial Lung Cancer" project.

pht003387
Descripción

pht003387

Alias
UMLS CUI [1,1]
C3846158
De-identified subject ID
Descripción

Subject_id

Tipo de datos

text

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Lung cancer case/control status
Descripción

case_control_status

Tipo de datos

text

Alias
UMLS CUI [1,1]
C3274646
Age at disease diagnosis or blood draw
Descripción

age

Tipo de datos

text

Unidades de medida
  • years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C2316983
UMLS CUI [2,1]
C0001779
UMLS CUI [2,2]
C0190979
Race of participant
Descripción

race

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0034510
Gender of participant
Descripción

sex

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0079399
Ever/never smoking history
Descripción

smoking_history

Tipo de datos

text

Alias
UMLS CUI [1,1]
C1519384
Subject's pack years
Descripción

pack_years

Tipo de datos

float

Unidades de medida
  • pack years
Alias
UMLS CUI [1,1]
C1277691
pack years
Site
Descripción

site

Tipo de datos

text

Alias
UMLS CUI [1,1]
C1515974

Similar models

Subject ID, case or control status, age, race, sex, smoking history, and number of cigarette packs per year of participants affected or not affected with familial lung cancer and involved in the "Genetic Epidemiology of Lung Cancer Consortium GWAS of Familial Lung Cancer" project.

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
pht003387
C3846158 (UMLS CUI [1,1])
Subject_id
Item
De-identified subject ID
text
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Item
Lung cancer case/control status
text
C3274646 (UMLS CUI [1,1])
Code List
Lung cancer case/control status
CL Item
Control (0)
C3274648 (UMLS CUI [1,1])
CL Item
Case (1)
C3274647 (UMLS CUI [1,1])
Item
Age at disease diagnosis or blood draw
text
C0001779 (UMLS CUI [1,1])
C2316983 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2,1])
C0190979 (UMLS CUI [2,2])
Code List
Age at disease diagnosis or blood draw
CL Item
Unknown (9999)
Item
Race of participant
text
C0034510 (UMLS CUI [1,1])
Code List
Race of participant
CL Item
Asian/Pacific (A)
CL Item
African American (B)
CL Item
Caucasian (C)
CL Item
Unknown (U)
Item
Gender of participant
text
C0079399 (UMLS CUI [1,1])
Code List
Gender of participant
CL Item
Unknown (0)
CL Item
Male (1)
C0086582 (UMLS CUI [1,1])
CL Item
Female (2)
C0086287 (UMLS CUI [1,1])
Item
Ever/never smoking history
text
C1519384 (UMLS CUI [1,1])
Code List
Ever/never smoking history
CL Item
Never (0)
CL Item
Ever (1)
CL Item
Unknown (9999)
pack_years
Item
Subject's pack years
float
C1277691 (UMLS CUI [1,1])
site
Item
Site
text
C1515974 (UMLS CUI [1,1])

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