ID

45432

Beschrijving

Principal Investigator: Ann G. Schwartz, PhD, MPH, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA MeSH: Lung Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000629 Familial lung cancer cases were collected by the Genetic Epidemiology of Lung Cancer Consortium (GELCC) recruitment sites: University of Cincinnati, Karmanos Cancer Institute at Wayne State University, Louisiana State University Health Sciences Center-New Orleans, Mayo Clinic, and Medical College of Ohio. Familial cases for this study came from three sources: 1) one case each from families (at least 3 affected lung cancer cases in the family) included in the linkage analysis; 2) one case from linkage-eligible families (at least 3 affected lung cancer cases in the family) but where there were insufficient biospecimens available to make them informative for linkage analysis; and 3) one case from families not eligible for the linkage study with a family history of at least one first or second degree relative affected with lung cancer. Unrelated controls were selected from 1) among the spouses of family members, thus matching on socio-economic status (SES) and ethnicity (typically) of the cases or 2) from case-control studies of lung cancer conducted in the same location in which the linkage families were collected and matched on age, sex, and race. All cases and controls self-reported as European American. Biospecimens used for normal DNA extraction included blood, saliva or mouthwash. Some samples underwent whole genome amplication.

Link

dbGaP-study=phs000629

Trefwoorden

  1. 29-11-22 29-11-22 - Chiara Middel
Houder van rechten

Ann G. Schwartz, PhD, MPH, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA

Geüploaded op

29 november 2022

DOI

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Licentie

Creative Commons BY 4.0

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dbGaP phs000629 GWAS of Familial Lung Cancer

Subject ID, consent group, and affection status of participants affected or not affected with familial lung cancer and involved in the "Genetic Epidemiology of Lung Cancer Consortium GWAS of Familial Lung Cancer" project.

pht003385
Beschrijving

pht003385

Alias
UMLS CUI [1,1]
C3846158
De-identified subject ID
Beschrijving

SUBJECT_ID

Datatype

text

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Consent status
Beschrijving

CONSENT

Datatype

text

Alias
UMLS CUI [1,1]
C0021430
Subject source
Beschrijving

SUBJECT_SOURCE

Datatype

text

Alias
UMLS CUI [1,1]
C0681850
UMLS CUI [1,2]
C0449416
Source subject ID
Beschrijving

SOURCE_SUBJECT_ID

Datatype

text

Alias
UMLS CUI [1,1]
C2348585
UMLS CUI [1,2]
C0449416

Similar models

Subject ID, consent group, and affection status of participants affected or not affected with familial lung cancer and involved in the "Genetic Epidemiology of Lung Cancer Consortium GWAS of Familial Lung Cancer" project.

Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
pht003385
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified subject ID
text
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Item
Consent status
text
C0021430 (UMLS CUI [1,1])
Code List
Consent status
CL Item
Subjects did not participate in the study, did not complete a consent document and are included only for the pedigree structure and/or genotype controls, such as HapMap subjects (0)
CL Item
Disease-Specific (Lung Cancer, IRB, COL, MDS) (DS-LC-IRB-COL-MDS) (1)
Item
Subject source
text
C0681850 (UMLS CUI [1,1])
C0449416 (UMLS CUI [1,2])
Code List
Subject source
CL Item
Control (0)
C3274648 (UMLS CUI [1,1])
CL Item
Lung cancer case (1)
SOURCE_SUBJECT_ID
Item
Source subject ID
text
C2348585 (UMLS CUI [1,1])
C0449416 (UMLS CUI [1,2])

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