ID

45432

Description

Principal Investigator: Ann G. Schwartz, PhD, MPH, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA MeSH: Lung Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000629 Familial lung cancer cases were collected by the Genetic Epidemiology of Lung Cancer Consortium (GELCC) recruitment sites: University of Cincinnati, Karmanos Cancer Institute at Wayne State University, Louisiana State University Health Sciences Center-New Orleans, Mayo Clinic, and Medical College of Ohio. Familial cases for this study came from three sources: 1) one case each from families (at least 3 affected lung cancer cases in the family) included in the linkage analysis; 2) one case from linkage-eligible families (at least 3 affected lung cancer cases in the family) but where there were insufficient biospecimens available to make them informative for linkage analysis; and 3) one case from families not eligible for the linkage study with a family history of at least one first or second degree relative affected with lung cancer. Unrelated controls were selected from 1) among the spouses of family members, thus matching on socio-economic status (SES) and ethnicity (typically) of the cases or 2) from case-control studies of lung cancer conducted in the same location in which the linkage families were collected and matched on age, sex, and race. All cases and controls self-reported as European American. Biospecimens used for normal DNA extraction included blood, saliva or mouthwash. Some samples underwent whole genome amplication.

Lien

dbGaP-study=phs000629

Mots-clés

  1. 29/11/2022 29/11/2022 - Chiara Middel
Détendeur de droits

Ann G. Schwartz, PhD, MPH, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA

Téléchargé le

29 novembre 2022

DOI

Pour une demande vous connecter.

Licence

Creative Commons BY 4.0

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dbGaP phs000629 GWAS of Familial Lung Cancer

Eligibility Criteria

Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
All cases must have had a lung cancer diagnosis and have at least one first or second degree relative with a lung cancer diagnosis. These cases must have provided a biospecimen suitable for the extraction of germline DNA. Controls were not related to cases and were drawn from the same geographic locations as the cases. All cases and controls were European American.
Description

Elig.phs000629.v1.p1.1

Type de données

boolean

Alias
UMLS CUI [1,1]
C1706256
UMLS CUI [1,2]
C0011900
UMLS CUI [1,3]
C0242379
UMLS CUI [1,4]
C1517194
UMLS CUI [1,5]
C1519210
UMLS CUI [2,1]
C0470187
UMLS CUI [2,2]
C2347026
UMLS CUI [2,3]
C0185115
UMLS CUI [2,4]
C2986526
UMLS CUI [3,1]
C0009932
UMLS CUI [3,2]
C1546988
UMLS CUI [3,3]
C1706256
UMLS CUI [3,4]
C0445247
UMLS CUI [3,5]
C0017446
UMLS CUI [4,1]
C1706256
UMLS CUI [4,2]
C0009932
UMLS CUI [4,3]
C0683983

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Type de données
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000629.v1.p1.1
Item
All cases must have had a lung cancer diagnosis and have at least one first or second degree relative with a lung cancer diagnosis. These cases must have provided a biospecimen suitable for the extraction of germline DNA. Controls were not related to cases and were drawn from the same geographic locations as the cases. All cases and controls were European American.
boolean
C1706256 (UMLS CUI [1,1])
C0011900 (UMLS CUI [1,2])
C0242379 (UMLS CUI [1,3])
C1517194 (UMLS CUI [1,4])
C1519210 (UMLS CUI [1,5])
C0470187 (UMLS CUI [2,1])
C2347026 (UMLS CUI [2,2])
C0185115 (UMLS CUI [2,3])
C2986526 (UMLS CUI [2,4])
C0009932 (UMLS CUI [3,1])
C1546988 (UMLS CUI [3,2])
C1706256 (UMLS CUI [3,3])
C0445247 (UMLS CUI [3,4])
C0017446 (UMLS CUI [3,5])
C1706256 (UMLS CUI [4,1])
C0009932 (UMLS CUI [4,2])
C0683983 (UMLS CUI [4,3])

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