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ID
45392
Beschrijving
Principal Investigator: Richard Weinshilboum, MD, Mayo Clinic MeSH: Leukemia, Lymphoid https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000621 The ECOG 2997 trial was a randomized controlled trial for patients with previously untreated CLL comparing fludarabine monotherapy to the combination of fludarabine and cyclophosphamide. The initial clinical findings of this study were published in the Journal of Clinical Oncology in 2007 (JCO 25:793-8). Additional laboratory studies have also published (JCO 25:799-804).
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- 15-11-22 15-11-22 - Simon Heim
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Richard Weinshilboum, MD, Mayo Clinic
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15 november 2022
DOI
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Creative Commons BY 4.0
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dbGaP phs000621 Genome Wide Association Studies in ECOG 2997 Trial
Sample ID, body site where sample was obtained, analyte type, tumor status, histological type of sample, primary metastatic tumor, primary tumor location, tumor stage, tumor grade, treatment of tumors obtained from participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, subject source, subject source ID, and affection status of participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- Subject ID, sample ID, plate for genotype, well within plate, sample source, sample source ID, and sample use variable of participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- Subject ID, age, sex, best confirmed response for treatment, progression-free survival censor, progression-free survival time, survival censor variable, toxicity due to grade 4 neutropenia, total number of treatment cycles, and rice of participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- Sample ID, body site where sample was obtained, analyte type, tumor status, histological type of sample, primary metastatic tumor, primary tumor location, tumor stage, tumor grade, treatment of tumors obtained from participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
Similar models
Sample ID, body site where sample was obtained, analyte type, tumor status, histological type of sample, primary metastatic tumor, primary tumor location, tumor stage, tumor grade, treatment of tumors obtained from participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, subject source, subject source ID, and affection status of participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- Subject ID, sample ID, plate for genotype, well within plate, sample source, sample source ID, and sample use variable of participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- Subject ID, age, sex, best confirmed response for treatment, progression-free survival censor, progression-free survival time, survival censor variable, toxicity due to grade 4 neutropenia, total number of treatment cycles, and rice of participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
- Sample ID, body site where sample was obtained, analyte type, tumor status, histological type of sample, primary metastatic tumor, primary tumor location, tumor stage, tumor grade, treatment of tumors obtained from participants with untreated chronic lymphocytic leukemia and involved in the "Genome Wide Association Studies in ECOG 2997 Trial" project.
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
SAMPLEID
Item
De-identified sample ID
text
C4684638 (UMLS CUI [1,1])
C1299222 (UMLS CUI [1,2])
C1299222 (UMLS CUI [1,2])
BODY_SITE
Item
Body site where sample was collected
string
C0449705 (UMLS CUI [1,1])
ANALYTE_TYPE
Item
Analyte type
string
C4744818 (UMLS CUI [1,1])
CL Item
Is not a tumor (N)
CL Item
Is Tumor (Y)
HISTOLOGICAL_TYPE
Item
Cell or tissue type or subtype of sample
string
C2347026 (UMLS CUI [1,1])
C0007634 (UMLS CUI [1,2])
C0332307 (UMLS CUI [1,3])
C2347026 (UMLS CUI [2,1])
C0007634 (UMLS CUI [2,2])
C0449560 (UMLS CUI [2,3])
C1292533 (UMLS CUI [3,1])
C0332307 (UMLS CUI [3,2])
C1292533 (UMLS CUI [4,1])
C0449560 (UMLS CUI [4,2])
C0007634 (UMLS CUI [1,2])
C0332307 (UMLS CUI [1,3])
C2347026 (UMLS CUI [2,1])
C0007634 (UMLS CUI [2,2])
C0449560 (UMLS CUI [2,3])
C1292533 (UMLS CUI [3,1])
C0332307 (UMLS CUI [3,2])
C1292533 (UMLS CUI [4,1])
C0449560 (UMLS CUI [4,2])
PRIMARY_METASTATIC_TUMOR
Item
Primary tumor, metastasis, or transformed cell line
string
C0677930 (UMLS CUI [1,1])
C0027627 (UMLS CUI [1,2])
C0007601 (UMLS CUI [1,3])
C0027627 (UMLS CUI [1,2])
C0007601 (UMLS CUI [1,3])
PRIMARY_TUMOR_LOCATION
Item
Primary tumor location
string
C0475447 (UMLS CUI [1,1])
TUMOR_STAGE
Item
Tumor stage of sample
text
C1300072 (UMLS CUI [1,1])
TUMOR_GRADE
Item
Tumor grade of sample
string
C0919553 (UMLS CUI [1,1])
TUMOR_TREATMENT
Item
Type of tumor treatment for sample
string
C0087111 (UMLS CUI [1,1])
C0027651 (UMLS CUI [1,2])
C0332307 (UMLS CUI [1,3])
C0027651 (UMLS CUI [1,2])
C0332307 (UMLS CUI [1,3])