ID
45377
Description
Principal Investigator: Chris Haiman, ScD, University of Southern California, Los Angeles, CA, USA MeSH: Breast Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000517 The Multiethnic Cohort Study is a population-based prospective cohort study (n=215,251) that was initiated between 1993 and 1996 and includes subjects from various ethnic groups - African Americans and Latinos primarily from Californian (great Los Angeles area) and Native Hawaiians, Japanese-Americans, and European Americans primarily from Hawaii. State drivers' license files were the primary sources used to identify study subjects in Hawaii and California. Additionally, in Hawaii, state voter's registration files were used, and, in California, Health Care Financing Administration (HCFA) files were used to identify additional African American study subjects. In the cohort, incident cancer cases are identified annually through cohort linkage to population-based cancer Surveillance, Epidemiology, and End Results (SEER) registries in Hawaii and Los Angeles County as well as to the California State cancer registry. Information on estrogen receptor status is also obtained through these registries. Blood sample collection in the MEC began in 1994 and targeted incident breast cancer cases and a random sample of study participants to serve as controls for genetic analyses. Subjects are frequency matched on age at blood draw and ethnicity. The following number of breast cancer cases and controls were genome-wide scanned as part of this study: African Americans, 473 cases and 464 controls; Japanese: 885 cases and 822 controls; Latinos, 520 cases and 544 controls.
Lien
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000517
Mots-clés
Versions (2)
- 07/11/2022 07/11/2022 - Simon Heim
- 13/12/2022 13/12/2022 - Kristina Keller
Détendeur de droits
Chris Haiman, ScD, University of Southern California, Los Angeles, CA, USA
Téléchargé le
7 novembre 2022
DOI
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Licence
Creative Commons BY 4.0
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dbGaP phs000517 Multiethnic Cohort (MEC) Breast Cancer Genetics
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants with or without breast cancer and involved in the "GWAS in African Americans, Latinos and Japanese" project.
- Sample ID, subject ID, and sample use variables obtained from participants with or without breast cancer and involved in the "GWAS in African Americans, Latinos and Japanese" project.
- Subject ID, ethnicity, gender, case or control of participant, neoplasm behavior, age at entry into cohort, age at diagnosis, age at blood draw, estrogen receptor status, and family history of breast cancer of participants with or without breast cancer and involved in the "GWAS in African Americans, Latinos and Japanese" project.
- Sample ID, body site where sample was obtained, anlalyte type, and tumor status of sample of participants involved in the "GWAS in African Americans, Latinos and Japanese" project.
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants with or without breast cancer and involved in the "GWAS in African Americans, Latinos and Japanese" project.
- Sample ID, subject ID, and sample use variables obtained from participants with or without breast cancer and involved in the "GWAS in African Americans, Latinos and Japanese" project.
- Subject ID, ethnicity, gender, case or control of participant, neoplasm behavior, age at entry into cohort, age at diagnosis, age at blood draw, estrogen receptor status, and family history of breast cancer of participants with or without breast cancer and involved in the "GWAS in African Americans, Latinos and Japanese" project.
- Sample ID, body site where sample was obtained, anlalyte type, and tumor status of sample of participants involved in the "GWAS in African Americans, Latinos and Japanese" project.
C0680251 (UMLS CUI [1,2])
C0680251 (UMLS CUI [1,2])
C0043210 (UMLS CUI [1,3])
C0001779 (UMLS CUI [1,4])
C0009247 (UMLS CUI [1,5])
C0085756 (UMLS CUI [1,6])
C1556094 (UMLS CUI [1,7])
C0086528 (UMLS CUI [1,8])