ID

45367

Description

Principal Investigator: Winnie S. Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA MeSH: Pancreatic Neoplasms,Carcinoma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000550 In this study, we whole genome sequenced tumor/normal pairs from three pancreatic adenocarcinoma patients to separately characterize each patient with respect to somatic alterations. For 2 patients for whom tumor RNA was available, we also performed RNA sequencing to evaluate gene expression changes. While additional sequencing is needed to improve our understanding of the disease, the information acquired from this study contributes to our knowledge base on pancreatic cancer and helps to establish a foundation for identifying and developing more efficacious treatments for patients.

Lien

dbGap-study=phs000550

Mots-clés

  1. 04/11/2022 04/11/2022 - Chiara Middel
Détendeur de droits

Winnie S. Liang, PhD, Translational Genomics Research Institute, Phoenix, AZ, USA

Téléchargé le

4 novembre 2022

DOI

Pour une demande vous connecter.

Licence

Creative Commons BY 4.0

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dbGaP phs000550 Characterization of Pancreatic Adenocarcinoma Patients Using NGS

Eligibility Criteria

Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Inclusion criteria: patients had to be ≥ 18 years of age and provided signed informed consent. These patients included those with a pathologic or clinical diagnosis of a pancreatic malignant neoplasm, or who were undergoing a medically indicated procedure to obtain tissue or to resect their pancreatic tumor. Other eligibility criteria included: Karnofsky performance status (PS) ≥ 80%, life expectancy > 3 months, baseline laboratory data indicating acceptable bone marrow reserve, liver, and renal function.
Description

Elig.phs000550.v1.p1.1

Type de données

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0001779
UMLS CUI [1,3]
C0021430
UMLS CUI [2,1]
C1521733
UMLS CUI [2,2]
C0011900
UMLS CUI [2,3]
C0346647
UMLS CUI [3,1]
C0332140
UMLS CUI [3,2]
C0346647
UMLS CUI [4,1]
C3872529
UMLS CUI [4,2]
C1301820
UMLS CUI [4,3]
C0040300
UMLS CUI [4,4]
C0030274
UMLS CUI [5,1]
C3872529
UMLS CUI [5,2]
C0728940
UMLS CUI [5,3]
C0346647
UMLS CUI [6,1]
C0205394
UMLS CUI [6,2]
C1512693
UMLS CUI [6,3]
C0206065
UMLS CUI [6,4]
C0023671
UMLS CUI [6,5]
C1442488
UMLS CUI [6,6]
C0022877
UMLS CUI [6,7]
C1511726
UMLS CUI [6,8]
C1879533
UMLS CUI [6,9]
C0005953
UMLS CUI [6,10]
C0232741
UMLS CUI [6,11]
C0232804

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Type de données
Alias
Item Group
Inclusion and exclusion criteria
Elig.phs000550.v1.p1.1
Item
Inclusion criteria: patients had to be ≥ 18 years of age and provided signed informed consent. These patients included those with a pathologic or clinical diagnosis of a pancreatic malignant neoplasm, or who were undergoing a medically indicated procedure to obtain tissue or to resect their pancreatic tumor. Other eligibility criteria included: Karnofsky performance status (PS) ≥ 80%, life expectancy > 3 months, baseline laboratory data indicating acceptable bone marrow reserve, liver, and renal function.
boolean
C1512693 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C0021430 (UMLS CUI [1,3])
C1521733 (UMLS CUI [2,1])
C0011900 (UMLS CUI [2,2])
C0346647 (UMLS CUI [2,3])
C0332140 (UMLS CUI [3,1])
C0346647 (UMLS CUI [3,2])
C3872529 (UMLS CUI [4,1])
C1301820 (UMLS CUI [4,2])
C0040300 (UMLS CUI [4,3])
C0030274 (UMLS CUI [4,4])
C3872529 (UMLS CUI [5,1])
C0728940 (UMLS CUI [5,2])
C0346647 (UMLS CUI [5,3])
C0205394 (UMLS CUI [6,1])
C1512693 (UMLS CUI [6,2])
C0206065 (UMLS CUI [6,3])
C0023671 (UMLS CUI [6,4])
C1442488 (UMLS CUI [6,5])
C0022877 (UMLS CUI [6,6])
C1511726 (UMLS CUI [6,7])
C1879533 (UMLS CUI [6,8])
C0005953 (UMLS CUI [6,9])
C0232741 (UMLS CUI [6,10])
C0232804 (UMLS CUI [6,11])

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