ID
45365
Beschreibung
Principal Investigator: Sandeep Dave, MD, MS, Duke University, Durham, NC, USA MeSH: Burkitt Lymphoma,Lymphoma, Non-Hodgkin https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000562 Burkitt lymphoma (BL) is characterized by deregulation of *MYC*, but the contribution of other genetic mutations to the disease is largely unknown. We sequenced exomes of 59 BL tumors, 14 of which had paired normal tissue. Our work elucidates commonly occurring gene-coding mutations in Burkitt lymphoma and implicates *ID3* as a novel tumor suppressor gene.
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- 04.11.22 04.11.22 - Chiara Middel
Rechteinhaber
Sandeep Dave, MD, MS, Duke University, Durham, NC, USA
Hochgeladen am
4. November 2022
DOI
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Lizenz
Creative Commons BY 4.0
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dbGaP phs000562 The Genetic Landscape of Mutations in Burkitt Lymphoma
Subject ID and consent group of participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- StudyEvent: SEV1
- Subject ID and consent group of participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- Subject ID, sample ID, and sample use variable obtained from participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- Subject ID, age onset, gender, and ethnicity of participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- Sample ID, body site where sample was collected, tumor status, histological type of samples, and analyte type of samples obtained from participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
Ähnliche Modelle
Subject ID and consent group of participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- StudyEvent: SEV1
- Subject ID and consent group of participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- Subject ID, sample ID, and sample use variable obtained from participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- Subject ID, age onset, gender, and ethnicity of participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.
- Sample ID, body site where sample was collected, tumor status, histological type of samples, and analyte type of samples obtained from participants with Burkitt lymphoma and involved in the "The Genetic Landscape of Mutations in Burkitt Lymphoma" project.