ID
45340
Descripción
Principal Investigator: Marie-Claude Gingras, PhD, Baylor College of Medicine, Human Genome Sequencing Center, Houston, TX, USA MeSH: Carcinoma, Pancreatic Ductal https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000516 Pancreatic ductal adenocarcinomas (PDAC) is the 11th most common cancer in the USA but the 4th in fatalities. The onset and progression of cancer is driven by extensive rearrangement and mutation of the genome. We combined our capability to capture and enrich exome DNA with the next generation sequencing capacity to allow us to detect and characterize the somatic mutation profile of 24 patients with PDAC. Patient samples were collected by the Elkins Pancreatic Center in the Baylor College of Medicine Department of Surgery. Sequencing of the pancreatic ductal adenocarcinoma is one of the NHGRI Center Initiated Projects in progress in the Human Genome Sequencing Center at Baylor College of Medicine. These data are also contributed to an ICGC study and will be published with the ICGC collaborators.
Link
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000516
Palabras clave
Versiones (2)
- 2/11/22 2/11/22 - Simon Heim
- 13/12/22 13/12/22 - Kristina Keller
Titular de derechos de autor
Marie-Claude Gingras, PhD, Baylor College of Medicine, Human Genome Sequencing Center, Houston, TX, USA
Subido en
2 de noviembre de 2022
DOI
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Licencia
Creative Commons BY 4.0
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dbGaP phs000516 Genome Sequencing of Pancreatic Ductal Adenocarcinoma
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, subject source, source subject ID, consent group, and affection status of participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
- Subject ID, sample ID, sample source, source sample ID, and sample use variable obtained from participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
- Subject ID, sex, age, smoking, amount the subject smoked, drinking, diabetes, BMI, family history of malignancy, status of subject at time of writing, follow up period after surgery, and subject's cause of death of participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
- Sample ID, tumor status of sample, histological type, histological subtype, tumor location, tumor stage, tumor grade, pathological staging of sample (pT) based on tumor characteristics, pathological staging of sample (pN) based on lymph node invasion, tumor size, presence of perinerual invasion, and analyte type of participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, subject source, source subject ID, consent group, and affection status of participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
- Subject ID, sample ID, sample source, source sample ID, and sample use variable obtained from participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
- Subject ID, sex, age, smoking, amount the subject smoked, drinking, diabetes, BMI, family history of malignancy, status of subject at time of writing, follow up period after surgery, and subject's cause of death of participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
- Sample ID, tumor status of sample, histological type, histological subtype, tumor location, tumor stage, tumor grade, pathological staging of sample (pT) based on tumor characteristics, pathological staging of sample (pN) based on lymph node invasion, tumor size, presence of perinerual invasion, and analyte type of participants with pancreatic ductal adenocarcinoma and involved in the "Genome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)" project.
C1335302 (UMLS CUI [1,2])
C0021430 (UMLS CUI [1,3])
C0679823 (UMLS CUI [1,4])
C0887950 (UMLS CUI [1,5])
C0035168 (UMLS CUI [1,6])