ID
45294
Descrição
Principal Investigator: Antonio Iavarone, MD, Columbia University, New York, NY, USA MeSH: Glioblastoma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000505 We used massively parallel, paired-end sequencing of expressed transcripts (RNA-seq) to detect novel gene fusions in short-term cultures of glioma stem-like cells freshly isolated from nine patients carrying primary glioblastoma multiforme (GBM). The culture of primary GBM tumors under serum-free conditions selects cells that retain phenotypes and genotypes closely mirroring primary tumor profiles as compared to serum-cultured glioma cell lines that have largely lost their developmental identities.
Link
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000505
Palavras-chave
Versões (2)
- 16/10/2022 16/10/2022 - Tabea Kampen
- 17/10/2022 17/10/2022 - Dr. Christian Niklas
Titular dos direitos
Antonio Iavarone, MD, Columbia University, New York, NY, USA
Transferido a
16 de outubro de 2022
DOI
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Licença
Creative Commons BY 4.0
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dbGaP phs000505 Gene Fusion Discovery through RNA Sequencing of Human Glioblastoma Stem Cell Lines
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- This data table contains subject IDs and consent group information.
- The data table contains mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- The sample attributes data table includes sample type, body site where sample was extracted, sample analyte type and histological type.
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Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- This data table contains subject IDs and consent group information.
- The data table contains mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- The sample attributes data table includes sample type, body site where sample was extracted, sample analyte type and histological type.
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