ID

45284

Description

Principal Investigator: Stephen Rich, PhD, University of Virginia, Charlottesville, VA, USA MeSH: Myocardial Infarction,Brain Ischemia https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000400 The NHLBI "Grand Opportunity" Exome Sequencing Project (GO-ESP), a signature project of the NHLBI Recovery Act investment, was designed to identify genetic variants in coding regions (exons) of the human genome (the "exome") that are associated with heart, lung and blood diseases. These and related diseases that are of high impact to public health and individuals from diverse racial and ethnic groups will be studied. These data may help researchers understand the causes of disease, contributing to better ways to prevent, diagnose, and treat diseases, as well as determine whether to tailor prevention and treatments to specific populations. This could lead to more effective treatments and reduce the likelihood of side effects. GO-ESP is comprised of five collaborative components: 3 cohort consortia - HeartGO, LungGO, and WHISP - and 2 sequencing centers - BroadGO and SeattleGO. HeartGO is a consortium of six well-phenotyped NHLBI cohorts: Atherosclerosis Risk in Communities (ARIC) study, the Coronary Artery Risk Development in Young Adults (CARDIA) study, the Cardiovascular Health Study, the Framingham Heart Study, the Jackson Heart Study, and the Multi-Ethnic Study of Atherosclerosis. Together, these cohorts have provided DNA and phenotype datasets from a diverse cohort of individuals of African-American, Caucasian, Asian, and Hispanic ancestry to be made available for use by qualified investigators in dbGaP. HeartGO investigators will conduct genotype-phenotype analyses for phenotypes related not only to heart disease but with other variables that will be contributed to dbGaP. The HeartGO dataset provides investigators with genotype-phenotype analytic opportunities for traits not only related to heart disease but also associated with ancillary variables that will be contributed to dbGaP, including disease endpoints, risk factors, biomarkers, and subclinical disease measures. The phenotypes planned for investigation as part of the GO-ESP HeartGO project include early-onset myocardial infarction (EOMI), low density lipoprotein (LDL) cholesterol, body mass index/type 2 diabetes (BMI/T2D), blood pressure and ischemic stroke. Results of the proposed analyses as well as relevant replication/follow-up analyses will be reported in peer-reviewed journals. This study phs000400 contains the Cardiovascular Health Study (CHS) subset of GO-ESP/Heart-GO. Additional GO-ESP data is also available via dbGaP.

Link

dbGaP study = phs000400

Keywords

Versions (1)
  1. 10/13/22 10/13/22 - Dr. Christian Niklas
Copyright Holder

Stephen Rich, PhD, University of Virginia, Charlottesville, VA, USA

Uploaded on

October 13, 2022

DOI

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License

Creative Commons BY 4.0
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dbGaP phs000400 NHLBI GO-ESP: Heart Cohorts Exome Sequencing Project (CHS)

English

The dataset is focused on LDL data (extremely high/low) of participating subjects of two ethnic groups (Caucasian/African American). In addition to various lipid values, medical background information provides data about blood/urine laboratory values, EKG results, medication taken, body measurements (e.g. height, weight, BMI), the occurrence of cardio-vascular related diagnoses, e.g. diabetes, MI, stroke (including family history), and gender, age of subjects.

4 forms  
pht002536
Description

pht002536

Alias
UMLS CUI [1,1]
C3846158
Cohort name
Description

ESP_COHORT

Data type

string

Alias
UMLS CUI [1,1]
C0599755
UMLS CUI [1,2]
C0027365
De-identified subject ID
Description

SUBJID

Data type

string

Alias
UMLS CUI [1,1]
C2348585
UMLS CUI [1,2]
C4684638
Values: EOMI_Case (Early MI case); EOMI_Control (Early MI control; LDL_High; LDL_Low
Description

ESP_PHENOTYPE

Data type

string

Alias
UMLS CUI [1,1]
C3274648
UMLS CUI [1,2]
C4014367
UMLS CUI [2,1]
C3274647
UMLS CUI [2,2]
C4014367
Information from quality control analysis
Description

SAMPLE_QC_INFO

Data type

string

Alias
UMLS CUI [1,1]
C0034378
UMLS CUI [1,2]
C0936012
Information about known duplicates and related
Description

DUP_RELATED_INFO

Data type

string

Alias
UMLS CUI [1,1]
C3846158
Values: European American; African American
Description

ESP_RACE

Data type

string

Alias
UMLS CUI [1,1]
C3853635
UMLS CUI [1,2]
C0683983
UMLS CUI [2,1]
C3853635
UMLS CUI [2,2]
C0085756
Values: Male; Female
Description

ESP_SEX

Data type

string

Alias
UMLS CUI [1,1]
C0079399
UMLS CUI [1,2]
C0086582
UMLS CUI [2,1]
C0079399
UMLS CUI [2,2]
C0086287
Clinic or field center within cohort
Description

ESP_STUDY_SITE

Data type

string

Alias
UMLS CUI [1,1]
C3846158
Age in years at baseline
Description

ESP_AGE_BASELINE

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C1442488
Years
MI status at baseline [0=No, 1=Yes]
Description

ESP_MI_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0027051
UMLS CUI [1,2]
C1442488
0/1 - to indicate that an MI occurred during study follow up. 0 - if no MI during study follow up. 1 - if an adjudicated MI occurred during study follow up (even if baseline MI status was 1).
Description

ESP_MI_DURING_FOLLOWUP

Data type

text

Alias
UMLS CUI [1,1]
C0027051
UMLS CUI [1,2]
C1522577
Time to event variable for MI. Time (in days) from start of study to MI for event that occurred during study follow up; and follow up time for those that did not have an MI during study follow up.
Description

ESP_MI_TTE_OR_CENSOR

Data type

text

Measurement units
  • Days
Alias
UMLS CUI [1,1]
C0027051
UMLS CUI [1,2]
C1522577
UMLS CUI [2,1]
C0027051
UMLS CUI [2,2]
C1518422
UMLS CUI [2,3]
C1522577
UMLS CUI [2,4]
C0040223
Days
Framingham Risk Score predicted probably calculated at baseline (was not calculated for those with baseline history of MI).
Description

ESP_FRS_CHDPROB_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C3176199
UMLS CUI [1,2]
C1442488
Baseline BMI in kg/m2
Description

ESP_BMI_BASELINE

Data type

text

Measurement units
  • kg/m2
Alias
UMLS CUI [1,1]
C1305855
UMLS CUI [1,2]
C1442488
kg/m2
Type 2 diabetes status at baseline [0=No, 1=Yes]
Description

ESP_T2DIABETES_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C4014362
UMLS CUI [1,2]
C1442488
Weight in kg. at baseline
Description

ESP_WEIGHT_BASELINE

Data type

text

Measurement units
  • kg
Alias
UMLS CUI [1,1]
C0005910
UMLS CUI [1,2]
C1442488
kg
Waist in cm at baseline
Description

ESP_WAIST_BASELINE

Data type

text

Measurement units
  • cm
Alias
UMLS CUI [1,1]
C0455829
UMLS CUI [1,2]
C1442488
cm
Waist to hip ratio at baseline
Description

ESP_WHR_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0205682
UMLS CUI [1,2]
C1442488
Standing height in cm at baseline
Description

ESP_HEIGHT_BASELINE

Data type

text

Measurement units
  • cm
Alias
UMLS CUI [1,1]
C0005890
UMLS CUI [1,2]
C0231472
UMLS CUI [1,3]
C1442488
cm
Baseline calculated LDL in mg/dL (missing where trigs>400)
Description

ESP_LDL_BASELINE

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C2209033
UMLS CUI [1,2]
C1442488
mg/dL
HDL level in mg/dL at baseline
Description

ESP_HDL_BASELINE

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C0428472
UMLS CUI [1,2]
C1442488
mg/dL
Triglycerides at baseline in mg/dL
Description

ESP_TRIGS_BASELINE

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C0202236
UMLS CUI [1,2]
C1442488
mg/dL
Total cholesterol at baseline in mg/dL
Description

ESP_TOTCHOL_BASELINE

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C1445957
UMLS CUI [1,2]
C1442488
mg/dL
Any lipid lowering medication (statin or other) at baseline
Description

ESP_LIPID_MED_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0086440
UMLS CUI [1,2]
C1442488
Systolic blood pressure at baseline (avg. of 2 measurements), in mm Hg
Description

ESP_SBP_BASELINE

Data type

text

Measurement units
  • mm Hg
Alias
UMLS CUI [1,1]
C0871470
UMLS CUI [1,2]
C1442488
mm Hg
Diastolic blood pressure at baseline (avg. of 2 measurements), in mm Hg
Description

ESP_DBP_BASELINE

Data type

text

Measurement units
  • mm Hg
Alias
UMLS CUI [1,1]
C0428883
UMLS CUI [1,2]
C1442488
mm Hg
Physician diagnosed hypertension status at baseline [0=No, 1=Yes]
Description

ESP_HTN_STATUS_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0020538
UMLS CUI [1,2]
C1442488
Hypertension medication status (any) at baseline [0=No, 1=Yes]
Description

ESP_HTN_MED_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0003364
UMLS CUI [1,2]
C1442488
Stroke status at baseline [0=No, 1=Yes]
Description

ESP_STROKE_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0038454
UMLS CUI [1,2]
C1442488
0/1 - to indicate that a stroke occurred during study follow up. 0 - if no stroke during study follow up. 1 - if an adjudicated stroke occurred during study follow up (even if baseline stroke status was 1).
Description

ESP_STROKE_DURING_FOLLOWUP

Data type

text

Alias
UMLS CUI [1,1]
C0038454
UMLS CUI [1,2]
C1522577
Time to event variable for stroke. Time (in days) from start of study to stroke for event that occurred during study follow up; and follow up time for those that did not have an stroke during study follow up.
Description

ESP_STROKE_TTE_OR_CENSOR

Data type

text

Measurement units
  • Days
Alias
UMLS CUI [1,1]
C0038454
UMLS CUI [1,2]
C1522577
UMLS CUI [2,1]
C0038454
UMLS CUI [2,2]
C1518422
UMLS CUI [2,3]
C1522577
UMLS CUI [2,4]
C0040223
Days
Incident stroke subtype (Lacune or LVAth). Subtype is available only on a subset of samples, so will be missing for some with non-missing age at incident stroke.
Description

ESP_INC_STROKE_SUBTYPE

Data type

text

Alias
UMLS CUI [1,1]
C0038454
UMLS CUI [1,2]
C0449560
Family history (first degree relatives) of stroke at baseline [0=No, 1=Yes]
Description

ESP_STROKE_FAMHX_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C1261367
UMLS CUI [1,2]
C1442488
Current smoking status at baseline [0=No, 1=Yes]
Description

ESP_CURRENT_SMOKER_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C1519386
UMLS CUI [1,2]
C1442488
Former smoking status at baseline [0=No, 1=Yes]
Description

ESP_FORMER_SMOKER_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0337671
UMLS CUI [1,2]
C1442488
Age at menarche
Description

ESP_AGE_AT_MENARCHE

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C1314691
Years
Age categories for menarche
Description

ESP_AGE_AT_MENARCHE_CAT

Data type

text

Alias
UMLS CUI [1,1]
C1314691
UMLS CUI [1,2]
C0683312
Atrial fibrillation at baseline [0=No, 1=Yes]
Description

ESP_AFIB_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0004238
UMLS CUI [1,2]
C1442488
0/1 - to indicate that an atrial fibrillation occurred during study follow up. 0 - if no atrial fibrillation during study follow up. 1 - if an adjudicated atrial fibrillation occurred during study follow up.
Description

ESP_AFIB_DURING_FOLLOWUP

Data type

text

Alias
UMLS CUI [1,1]
C0004238
UMLS CUI [1,2]
C1522577
Time to event variable for atrial fibrillation (afib). Time (in days) from start of study to afib for event that occurred during study follow up; and follow up time for those that did not have an atrial fibrillation during study follow up.
Description

ESP_AFIB_TTE_OR_CENSOR

Data type

text

Measurement units
  • Days
Alias
UMLS CUI [1,1]
C0004238
UMLS CUI [1,2]
C1522577
UMLS CUI [2,1]
C0004238
UMLS CUI [2,2]
C1518422
UMLS CUI [2,3]
C1522577
UMLS CUI [2,4]
C0040223
Days
Blood fasting insulin at baseline in uU/mL. (Note that there are some extreme outliers)
Description

ESP_FASTINSULIN_BASELINE

Data type

text

Measurement units
  • uU/mL
Alias
UMLS CUI [1,1]
C0853230
UMLS CUI [1,2]
C0015663
UMLS CUI [1,3]
C1442488
uU/mL
Blood fasting glucose at baseline in mg/dL
Description

ESP_FASTGLUCOSE_BASELINE

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C0428568
UMLS CUI [1,2]
C1442488
mg/dL
Fibrinogen level in mg/dL at first designated visit (may not be baseline)
Description

ESP_FIBRINOGEN

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C1318051
UMLS CUI [1,2]
C4019187
mg/dL
Age in years at Fibrinogen measurement
Description

ESP_AGE_AT_FIBRINOGEN

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0337428
UMLS CUI [1,2]
C0001779
Years
Factor VII level in % at designated visit (may not be baseline)
Description

ESP_FACTORVII

Data type

text

Measurement units
  • %
Alias
UMLS CUI [1,1]
C0427593
UMLS CUI [1,2]
C0589121
%
Age in years at Factor VII measurement
Description

ESP_AGE_AT_FACTORVII

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C2825856
UMLS CUI [1,2]
C0001779
Years
Factor VIII level in % at designated visit (may not be baseline)
Description

ESP_FACTORVIII

Data type

text

Measurement units
  • %
Alias
UMLS CUI [1,1]
C0457997
UMLS CUI [1,2]
C0589121
%
Age in years at Factor VIII measurement
Description

ESP_AGE_AT_FACTORVIII

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C2825857
UMLS CUI [1,2]
C0001779
Years
VWF level in % at designated visit (may not be baseline)
Description

ESP_vWF

Data type

text

Measurement units
  • %
Alias
UMLS CUI [1,1]
C0427585
UMLS CUI [1,2]
C0589121
%
Age in years at visit of hemostatic factors measurement
Description

ESP_AGE_AT_vWF

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0242485
UMLS CUI [1,2]
C0005515
UMLS CUI [1,3]
C0019116
UMLS CUI [1,4]
C0001779
Years
C-reactive protein level in mg/L at designated visit (may not be baseline)
Description

ESP_CRP

Data type

text

Measurement units
  • mg/L
Alias
UMLS CUI [1,1]
C0428528
UMLS CUI [1,2]
C0589121
mg/L
Age in years at CRP measurement
Description

ESP_AGE_AT_CRP

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0201657
UMLS CUI [1,2]
C0001779
Years
IL6 level in pg/mL at designated visit (may not be baseline)
Description

ESP_IL6

Data type

text

Measurement units
  • pg/mL
Alias
UMLS CUI [1,1]
C0021760
UMLS CUI [1,2]
C0589121
pg/mL
Age in years at IL6 measurement
Description

ESP_AGE_AT_IL6

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0242485
UMLS CUI [1,2]
C0021760
UMLS CUI [1,3]
C0001779
Years
ICAM1 level in ng/mL at designated visit (may not be baseline)
Description

ESP_ICAM1

Data type

text

Measurement units
  • ng/mL
Alias
UMLS CUI [1,1]
C4084871
UMLS CUI [1,2]
C0589121
ng/mL
Age in years at ICAM1 measurement
Description

ESP_AGE_AT_ICAM1

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C4084871
UMLS CUI [1,2]
C0001779
Years
P-selectin level at designated visit (may not be baseline)
Description

ESP_PSELECTIN

Data type

text

Alias
UMLS CUI [1,1]
C3890352
UMLS CUI [1,2]
C0589121
Age in years at P-selectin measurement
Description

ESP_AGE_AT_PSELECTIN

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C3890352
UMLS CUI [1,2]
C0001779
Years
White blood count in x1,000/cubic mm at designated visit (may not be baseline)
Description

ESP_WBC

Data type

text

Measurement units
  • x1000/cubic mm
Alias
UMLS CUI [1,1]
C1821144
UMLS CUI [1,2]
C0589121
x1000/cubic mm
Age in years at WBC measurement
Description

ESP_AGE_AT_WBC

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0023508
UMLS CUI [1,2]
C0001779
Years
Hemoglobin at designated visit (may not be baseline) in g/dl
Description

ESP_HEMOGLOBIN

Data type

text

Measurement units
  • g/dL
Alias
UMLS CUI [1,1]
C0518015
UMLS CUI [1,2]
C0589121
g/dL
Age in years at hemoglobin measurement
Description

ESP_AGE_AT_HEMOGLOBIN

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0518015
UMLS CUI [1,2]
C0001779
Years
Hematocrit at designated visit (may not be baseline) in %
Description

ESP_HEMATOCRIT

Data type

text

Measurement units
  • %
Alias
UMLS CUI [1,1]
C0518014
UMLS CUI [1,2]
C0589121
%
Age in years at hematocrit measurement
Description

ESP_AGE_AT_HEMATOCRIT

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0518014
UMLS CUI [1,2]
C0242485
UMLS CUI [1,3]
C0001779
Years
Platelet count at designated visit (may not be baseline) in x 1000/cubic mm
Description

ESP_PLATELET_COUNT

Data type

text

Measurement units
  • x1000/cubic mm
Alias
UMLS CUI [1,1]
C0032181
UMLS CUI [1,2]
C0589121
x1000/cubic mm
Age in years at platelet count measurement
Description

ESP_AGE_AT_PLATELET_COUNT

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0032181
UMLS CUI [1,2]
C0001779
Years
Mean corpuscular volume in femtoliters at designated visit (may not be baseline)
Description

ESP_MEAN_CORPUSCULAR_VOLUME

Data type

text

Measurement units
  • fL
Alias
UMLS CUI [1,1]
C1948043
UMLS CUI [1,2]
C0589121
fL
Age in years at mean corpuscular volume measurement
Description

ESP_AGE_AT_MCV

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C1948043
UMLS CUI [1,2]
C0001779
Years
Red blood cell count in million cells per microliter at designated visit (may not be baseline)
Description

ESP_RED_BLOOD_COUNT

Data type

text

Alias
UMLS CUI [1,1]
C0014772
UMLS CUI [1,2]
C0589121
Age in years at red blood cell count measurement
Description

ESP_AGE_AT_RBC

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0014772
UMLS CUI [1,2]
C0001779
Years
Neutrophils in absolute numbers at designated visit (may not be baseline).
Description

ESP_NEUTROPHILS

Data type

text

Alias
UMLS CUI [1,1]
C0948762
UMLS CUI [1,2]
C0589121
Monocytes in absolute numbers at designated visit (may not be baseline).
Description

ESP_MONOCYTES

Data type

text

Alias
UMLS CUI [1,1]
C5243958
UMLS CUI [1,2]
C0589121
Lymphocytes in absolute numbers at designated visit (may not be baseline).
Description

ESP_LYMPHOCYTES

Data type

text

Alias
UMLS CUI [1,1]
C3544087
UMLS CUI [1,2]
C0589121
Eosinophils in absolute numbers at designated visit (may not be baseline).
Description

ESP_EOSINOPHILS

Data type

text

Alias
UMLS CUI [1,1]
C0750879
UMLS CUI [1,2]
C0589121
Basophils in absolute numbers at designated visit (may not be baseline)
Description

ESP_BASOPHILS

Data type

text

Alias
UMLS CUI [1,1]
C1883362
UMLS CUI [1,2]
C0589121
Age in years at secondary blood count measurements (MCV, RBC, Neutrophils, Monocytes, Lymphocytes, Eosinophils, Basophils)
Description

ESP_AGE_AT_SECONDARY_BLOOD_COUNT

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0009555
UMLS CUI [1,2]
C0001779
Years
Baseline angioplasty status [ 0=No, 1=Yes]
Description

ESP_ANGIOPLASTY_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0162577
UMLS CUI [1,2]
C1442488
Baseline CABG status [ 0=No, 1=Yes]
Description

ESP_CABG_BASELINE

Data type

text

Alias
UMLS CUI [1,1]
C0010055
UMLS CUI [1,2]
C1442488
Coronary artery calcium Agatston total score
Description

ESP_CAC_AGATSTON_SCORE

Data type

text

Alias
UMLS CUI [1,1]
C2825178
Age in years at CAC Agatston score measurement
Description

ESP_AGE_AT_CAC

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C3484386
UMLS CUI [1,2]
C0001779
Years
Average far wall thickness of the right and left common carotid mean IMT values, using as many views as are available for a given study.
Description

ESP_IMT_MEANMEAN_FARWALL_CCA

Data type

text

Alias
UMLS CUI [1,1]
C0442071
UMLS CUI [1,2]
C0444504
UMLS CUI [1,3]
C0226086
UMLS CUI [1,4]
C0226087
UMLS CUI [1,5]
C1960467
UMLS CUI [1,6]
C0444504
Average far wall thickness of the right and left internal carotid maximum IMT values, using as many views as are available for a given study.
Description

ESP_IMT_MEANMEAN_FARWALL_ICA

Data type

text

Alias
UMLS CUI [1,1]
C0444504
UMLS CUI [1,2]
C0442071
UMLS CUI [1,3]
C0226157
UMLS CUI [1,4]
C0226156
UMLS CUI [1,5]
C1960467
UMLS CUI [1,6]
C0806909
Presence of any plaque, as determined by IMT at designated visit (may not be baseline).
Description

ESP_IMT_ANYPLAQUE

Data type

text

Alias
UMLS CUI [1,1]
C2936350
UMLS CUI [1,2]
C1960467
UMLS CUI [1,3]
C0589121
Age in years at IMT measurement
Description

ESP_AGE_AT_IMT

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0242485
UMLS CUI [1,2]
C1960467
UMLS CUI [1,3]
C0001779
Years
QRS interval from EKG at designated visit (may not be baseline)
Description

ESP_EKG_QRS

Data type

text

Alias
UMLS CUI [1,1]
C0429025
UMLS CUI [1,2]
C0589121
RR interval from EKG at designated visit (may not be baseline)
Description

ESP_EKG_RR

Data type

text

Alias
UMLS CUI [1,1]
C0489636
UMLS CUI [1,2]
C0589121
QT interval from EKG at designated visit (may not be baseline)
Description

ESP_EKG_QT

Data type

text

Alias
UMLS CUI [1,1]
C0429028
UMLS CUI [1,2]
C0589121
PR interval from EKG at designated visit (may not be baseline)
Description

ESP_EKG_PR

Data type

text

Alias
UMLS CUI [1,1]
C0429024
UMLS CUI [1,2]
C0589121
HR interval from EKG at designated visit (may not be baseline)
Description

ESP_EKG_HR

Data type

text

Alias
UMLS CUI [1,1]
C3846158
Left ventriculat hypertrophy status at baseline [0=No, 1=Yes]
Description

ESP_LVH_AT_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0149721
UMLS CUI [1,2]
C1442488
Atrial flutter at EKG
Description

ESP_AFLUT_AT_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0004239
Wolf-Parkinson-White pattern
Description

ESP_WPW_AT_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0043202
Second degree AV block
Description

ESP_AVBLOCK2_AT_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0264906
Third degree AV block
Description

ESP_AVBLOCK3_AT_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0151517
Cornell voltage for EKG measurement, for EKG group.
Description

ESP_CORNELL_VOLTAGE_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0428967
UMLS CUI [1,2]
C0149721
Pacer at EKG
Description

ESP_PACER_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0030163
UMLS CUI [1,2]
C0438154
Digoxin, for EKG group
Description

ESP_DIGOXIN_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0012265
Dihydropyridine calcium channel blockers
Description

ESP_DIHYDRO_CALCIUM_CHANNEL_BLOC

Data type

text

Alias
UMLS CUI [1,1]
C2945601
Non-dihydropyridine calcium channel blockers, for EKG group
Description

ESP_NONDIHYDRO_CALCIUM_CHANNEL_B

Data type

text

Alias
UMLS CUI [1,1]
C0006684
UMLS CUI [1,2]
C0332300
UMLS CUI [1,3]
C2945601
Any Calcium Channel blocker (only for ARIC - other HeartGO cohorts have this broken down by Dihydro versus Non-Dihydro)
Description

ESP_CALCIUM_CHANNEL_BLOCKERS_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0006684
UMLS CUI [1,2]
C1552551
Betablockers, for EKG group
Description

ESP_BETA_BLOCKERS_EKG

Data type

text

Alias
UMLS CUI [1,1]
C0001645
Age in years at EKG measurement
Description

ESP_AGE_AT_EKG

Data type

text

Alias
UMLS CUI [1,1]
C1623258
UMLS CUI [1,2]
C0001779
Raw cystatin C (mg/L)
Description

ESP_SERUM_CYSTATINC

Data type

text

Measurement units
  • mg/L
Alias
UMLS CUI [1,1]
C1619716
mg/L
Age in years at serum cystatin c measurement
Description

ESP_AGE_AT_SERUM_CYSTATINC

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C1619716
UMLS CUI [1,2]
C0001779
Years
Uric acid in mg/dL
Description

ESP_URIC_ACID

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C0202239
mg/dL
Age in years at uric acid measurement
Description

ESP_AGE_AT_URIC_ACID

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0202239
UMLS CUI [1,2]
C0001779
Years
Raw urinary albumin. Note: Users need to confirm units are the same across cohorts
Description

ESP_URINARY_ALBUMIN

Data type

text

Alias
UMLS CUI [1,1]
C0587185
Age in years at urinary albumin measurement
Description

ESP_AGE_AT_URINARY_ALBUMIN

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C1318429
UMLS CUI [1,2]
C0001779
Years
Raw urinary creatinine in mg/dL
Description

ESP_URINARY_CREATININE

Data type

text

Measurement units
  • mg/dL
Alias
UMLS CUI [1,1]
C1318439
mg/dL
Age in years at urinary creatinine measurement
Description

ESP_AGE_AT_URINARY_CREATININE

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C1318439
UMLS CUI [1,2]
C0001779
Years
May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study.
Description

ESP_GOUT

Data type

text

Alias
UMLS CUI [1,1]
C0018099
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Similar models

The dataset is focused on LDL data (extremely high/low) of participating subjects of two ethnic groups (Caucasian/African American). In addition to various lipid values, medical background information provides data about blood/urine laboratory values, EKG results, medication taken, body measurements (e.g. height, weight, BMI), the occurrence of cardio-vascular related diagnoses, e.g. diabetes, MI, stroke (including family history), and gender, age of subjects.

4 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht002536
C3846158 (UMLS CUI [1,1])
ESP_COHORT
Item
Cohort name
string
C0599755 (UMLS CUI [1,1])
C0027365 (UMLS CUI [1,2])
SUBJID
Item
De-identified subject ID
string
C2348585 (UMLS CUI [1,1])
C4684638 (UMLS CUI [1,2])
ESP_PHENOTYPE
Item
Values: EOMI_Case (Early MI case); EOMI_Control (Early MI control; LDL_High; LDL_Low
string
C3274648 (UMLS CUI [1,1])
C4014367 (UMLS CUI [1,2])
C3274647 (UMLS CUI [2,1])
C4014367 (UMLS CUI [2,2])
SAMPLE_QC_INFO
Item
Information from quality control analysis
string
C0034378 (UMLS CUI [1,1])
C0936012 (UMLS CUI [1,2])
DUP_RELATED_INFO
Item
Information about known duplicates and related
string
C3846158 (UMLS CUI [1,1])
ESP_RACE
Item
Values: European American; African American
string
C3853635 (UMLS CUI [1,1])
C0683983 (UMLS CUI [1,2])
C3853635 (UMLS CUI [2,1])
C0085756 (UMLS CUI [2,2])
ESP_SEX
Item
Values: Male; Female
string
C0079399 (UMLS CUI [1,1])
C0086582 (UMLS CUI [1,2])
C0079399 (UMLS CUI [2,1])
C0086287 (UMLS CUI [2,2])
ESP_STUDY_SITE
Item
Clinic or field center within cohort
string
C3846158 (UMLS CUI [1,1])
ESP_AGE_BASELINE
Item
Age in years at baseline
text
C0001779 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
MI status at baseline [0=No, 1=Yes]
text
C0027051 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_MI_BASELINE
Code List
MI status at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
0/1 - to indicate that an MI occurred during study follow up. 0 - if no MI during study follow up. 1 - if an adjudicated MI occurred during study follow up (even if baseline MI status was 1).
text
C0027051 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
ESP_MI_DURING_FOLLOWUP
Code List
0/1 - to indicate that an MI occurred during study follow up. 0 - if no MI during study follow up. 1 - if an adjudicated MI occurred during study follow up (even if baseline MI status was 1).
CL Item
No (0)
CL Item
Yes (1)
ESP_MI_TTE_OR_CENSOR
Item
Time to event variable for MI. Time (in days) from start of study to MI for event that occurred during study follow up; and follow up time for those that did not have an MI during study follow up.
text
C0027051 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
C0027051 (UMLS CUI [2,1])
C1518422 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])
C0040223 (UMLS CUI [2,4])
ESP_FRS_CHDPROB_BASELINE
Item
Framingham Risk Score predicted probably calculated at baseline (was not calculated for those with baseline history of MI).
text
C3176199 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_BMI_BASELINE
Item
Baseline BMI in kg/m2
text
C1305855 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
Type 2 diabetes status at baseline [0=No, 1=Yes]
text
C4014362 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_T2DIABETES_BASELINE
Code List
Type 2 diabetes status at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
ESP_WEIGHT_BASELINE
Item
Weight in kg. at baseline
text
C0005910 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_WAIST_BASELINE
Item
Waist in cm at baseline
text
C0455829 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_WHR_BASELINE
Item
Waist to hip ratio at baseline
text
C0205682 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_HEIGHT_BASELINE
Item
Standing height in cm at baseline
text
C0005890 (UMLS CUI [1,1])
C0231472 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])
ESP_LDL_BASELINE
Item
Baseline calculated LDL in mg/dL (missing where trigs>400)
text
C2209033 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_HDL_BASELINE
Item
HDL level in mg/dL at baseline
text
C0428472 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_TRIGS_BASELINE
Item
Triglycerides at baseline in mg/dL
text
C0202236 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_TOTCHOL_BASELINE
Item
Total cholesterol at baseline in mg/dL
text
C1445957 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
Any lipid lowering medication (statin or other) at baseline
text
C0086440 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_LIPID_MED_BASELINE
Code List
Any lipid lowering medication (statin or other) at baseline
CL Item
No (0)
CL Item
Yes (1)
ESP_SBP_BASELINE
Item
Systolic blood pressure at baseline (avg. of 2 measurements), in mm Hg
text
C0871470 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_DBP_BASELINE
Item
Diastolic blood pressure at baseline (avg. of 2 measurements), in mm Hg
text
C0428883 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Item
Physician diagnosed hypertension status at baseline [0=No, 1=Yes]
text
C0020538 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_HTN_STATUS_BASELINE
Code List
Physician diagnosed hypertension status at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
Hypertension medication status (any) at baseline [0=No, 1=Yes]
text
C0003364 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_HTN_MED_BASELINE
Code List
Hypertension medication status (any) at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
Stroke status at baseline [0=No, 1=Yes]
text
C0038454 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_STROKE_BASELINE
Code List
Stroke status at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
0/1 - to indicate that a stroke occurred during study follow up. 0 - if no stroke during study follow up. 1 - if an adjudicated stroke occurred during study follow up (even if baseline stroke status was 1).
text
C0038454 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
ESP_STROKE_DURING_FOLLOWUP
Code List
0/1 - to indicate that a stroke occurred during study follow up. 0 - if no stroke during study follow up. 1 - if an adjudicated stroke occurred during study follow up (even if baseline stroke status was 1).
CL Item
No (0)
CL Item
Yes (1)
ESP_STROKE_TTE_OR_CENSOR
Item
Time to event variable for stroke. Time (in days) from start of study to stroke for event that occurred during study follow up; and follow up time for those that did not have an stroke during study follow up.
text
C0038454 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
C0038454 (UMLS CUI [2,1])
C1518422 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])
C0040223 (UMLS CUI [2,4])
ESP_INC_STROKE_SUBTYPE
Item
Incident stroke subtype (Lacune or LVAth). Subtype is available only on a subset of samples, so will be missing for some with non-missing age at incident stroke.
text
C0038454 (UMLS CUI [1,1])
C0449560 (UMLS CUI [1,2])
Item
Family history (first degree relatives) of stroke at baseline [0=No, 1=Yes]
text
C1261367 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_STROKE_FAMHX_BASELINE
Code List
Family history (first degree relatives) of stroke at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
Current smoking status at baseline [0=No, 1=Yes]
text
C1519386 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_CURRENT_SMOKER_BASELINE
Code List
Current smoking status at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
Former smoking status at baseline [0=No, 1=Yes]
text
C0337671 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_FORMER_SMOKER_BASELINE
Code List
Former smoking status at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
ESP_AGE_AT_MENARCHE
Item
Age at menarche
text
C1314691 (UMLS CUI [1,1])
Item
Age categories for menarche
text
C1314691 (UMLS CUI [1,1])
C0683312 (UMLS CUI [1,2])
ESP_AGE_AT_MENARCHE_CAT
Code List
Age categories for menarche
CL Item
9 OR LESS (1)
CL Item
10 (2)
CL Item
11 (3)
CL Item
12 (4)
CL Item
13 (5)
CL Item
14 (6)
CL Item
15 (7)
CL Item
16 (8)
CL Item
17 OR OLDER (9)
Item
Atrial fibrillation at baseline [0=No, 1=Yes]
text
C0004238 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_AFIB_BASELINE
Code List
Atrial fibrillation at baseline [0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
0/1 - to indicate that an atrial fibrillation occurred during study follow up. 0 - if no atrial fibrillation during study follow up. 1 - if an adjudicated atrial fibrillation occurred during study follow up.
text
C0004238 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
ESP_AFIB_DURING_FOLLOWUP
Code List
0/1 - to indicate that an atrial fibrillation occurred during study follow up. 0 - if no atrial fibrillation during study follow up. 1 - if an adjudicated atrial fibrillation occurred during study follow up.
CL Item
No (0)
CL Item
Yes (1)
ESP_AFIB_TTE_OR_CENSOR
Item
Time to event variable for atrial fibrillation (afib). Time (in days) from start of study to afib for event that occurred during study follow up; and follow up time for those that did not have an atrial fibrillation during study follow up.
text
C0004238 (UMLS CUI [1,1])
C1522577 (UMLS CUI [1,2])
C0004238 (UMLS CUI [2,1])
C1518422 (UMLS CUI [2,2])
C1522577 (UMLS CUI [2,3])
C0040223 (UMLS CUI [2,4])
ESP_FASTINSULIN_BASELINE
Item
Blood fasting insulin at baseline in uU/mL. (Note that there are some extreme outliers)
text
C0853230 (UMLS CUI [1,1])
C0015663 (UMLS CUI [1,2])
C1442488 (UMLS CUI [1,3])
ESP_FASTGLUCOSE_BASELINE
Item
Blood fasting glucose at baseline in mg/dL
text
C0428568 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_FIBRINOGEN
Item
Fibrinogen level in mg/dL at first designated visit (may not be baseline)
text
C1318051 (UMLS CUI [1,1])
C4019187 (UMLS CUI [1,2])
ESP_AGE_AT_FIBRINOGEN
Item
Age in years at Fibrinogen measurement
text
C0337428 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_FACTORVII
Item
Factor VII level in % at designated visit (may not be baseline)
text
C0427593 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_FACTORVII
Item
Age in years at Factor VII measurement
text
C2825856 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_FACTORVIII
Item
Factor VIII level in % at designated visit (may not be baseline)
text
C0457997 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_FACTORVIII
Item
Age in years at Factor VIII measurement
text
C2825857 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_vWF
Item
VWF level in % at designated visit (may not be baseline)
text
C0427585 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_vWF
Item
Age in years at visit of hemostatic factors measurement
text
C0242485 (UMLS CUI [1,1])
C0005515 (UMLS CUI [1,2])
C0019116 (UMLS CUI [1,3])
C0001779 (UMLS CUI [1,4])
ESP_CRP
Item
C-reactive protein level in mg/L at designated visit (may not be baseline)
text
C0428528 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_CRP
Item
Age in years at CRP measurement
text
C0201657 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_IL6
Item
IL6 level in pg/mL at designated visit (may not be baseline)
text
C0021760 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_IL6
Item
Age in years at IL6 measurement
text
C0242485 (UMLS CUI [1,1])
C0021760 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
ESP_ICAM1
Item
ICAM1 level in ng/mL at designated visit (may not be baseline)
text
C4084871 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_ICAM1
Item
Age in years at ICAM1 measurement
text
C4084871 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_PSELECTIN
Item
P-selectin level at designated visit (may not be baseline)
text
C3890352 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_PSELECTIN
Item
Age in years at P-selectin measurement
text
C3890352 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_WBC
Item
White blood count in x1,000/cubic mm at designated visit (may not be baseline)
text
C1821144 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_WBC
Item
Age in years at WBC measurement
text
C0023508 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_HEMOGLOBIN
Item
Hemoglobin at designated visit (may not be baseline) in g/dl
text
C0518015 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_HEMOGLOBIN
Item
Age in years at hemoglobin measurement
text
C0518015 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_HEMATOCRIT
Item
Hematocrit at designated visit (may not be baseline) in %
text
C0518014 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_HEMATOCRIT
Item
Age in years at hematocrit measurement
text
C0518014 (UMLS CUI [1,1])
C0242485 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
ESP_PLATELET_COUNT
Item
Platelet count at designated visit (may not be baseline) in x 1000/cubic mm
text
C0032181 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_PLATELET_COUNT
Item
Age in years at platelet count measurement
text
C0032181 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_MEAN_CORPUSCULAR_VOLUME
Item
Mean corpuscular volume in femtoliters at designated visit (may not be baseline)
text
C1948043 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_MCV
Item
Age in years at mean corpuscular volume measurement
text
C1948043 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_RED_BLOOD_COUNT
Item
Red blood cell count in million cells per microliter at designated visit (may not be baseline)
text
C0014772 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_RBC
Item
Age in years at red blood cell count measurement
text
C0014772 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_NEUTROPHILS
Item
Neutrophils in absolute numbers at designated visit (may not be baseline).
text
C0948762 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_MONOCYTES
Item
Monocytes in absolute numbers at designated visit (may not be baseline).
text
C5243958 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_LYMPHOCYTES
Item
Lymphocytes in absolute numbers at designated visit (may not be baseline).
text
C3544087 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EOSINOPHILS
Item
Eosinophils in absolute numbers at designated visit (may not be baseline).
text
C0750879 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_BASOPHILS
Item
Basophils in absolute numbers at designated visit (may not be baseline)
text
C1883362 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_AGE_AT_SECONDARY_BLOOD_COUNT
Item
Age in years at secondary blood count measurements (MCV, RBC, Neutrophils, Monocytes, Lymphocytes, Eosinophils, Basophils)
text
C0009555 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
Item
Baseline angioplasty status [ 0=No, 1=Yes]
text
C0162577 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_ANGIOPLASTY_BASELINE
Code List
Baseline angioplasty status [ 0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
Item
Baseline CABG status [ 0=No, 1=Yes]
text
C0010055 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_CABG_BASELINE
Code List
Baseline CABG status [ 0=No, 1=Yes]
CL Item
No (0)
CL Item
Yes (1)
ESP_CAC_AGATSTON_SCORE
Item
Coronary artery calcium Agatston total score
text
C2825178 (UMLS CUI [1,1])
ESP_AGE_AT_CAC
Item
Age in years at CAC Agatston score measurement
text
C3484386 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_IMT_MEANMEAN_FARWALL_CCA
Item
Average far wall thickness of the right and left common carotid mean IMT values, using as many views as are available for a given study.
text
C0442071 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C0226086 (UMLS CUI [1,3])
C0226087 (UMLS CUI [1,4])
C1960467 (UMLS CUI [1,5])
C0444504 (UMLS CUI [1,6])
ESP_IMT_MEANMEAN_FARWALL_ICA
Item
Average far wall thickness of the right and left internal carotid maximum IMT values, using as many views as are available for a given study.
text
C0444504 (UMLS CUI [1,1])
C0442071 (UMLS CUI [1,2])
C0226157 (UMLS CUI [1,3])
C0226156 (UMLS CUI [1,4])
C1960467 (UMLS CUI [1,5])
C0806909 (UMLS CUI [1,6])
Item
Presence of any plaque, as determined by IMT at designated visit (may not be baseline).
text
C2936350 (UMLS CUI [1,1])
C1960467 (UMLS CUI [1,2])
C0589121 (UMLS CUI [1,3])
ESP_IMT_ANYPLAQUE
Code List
Presence of any plaque, as determined by IMT at designated visit (may not be baseline).
CL Item
No (0)
CL Item
Yes (1)
ESP_AGE_AT_IMT
Item
Age in years at IMT measurement
text
C0242485 (UMLS CUI [1,1])
C1960467 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
ESP_EKG_QRS
Item
QRS interval from EKG at designated visit (may not be baseline)
text
C0429025 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_RR
Item
RR interval from EKG at designated visit (may not be baseline)
text
C0489636 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_QT
Item
QT interval from EKG at designated visit (may not be baseline)
text
C0429028 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_PR
Item
PR interval from EKG at designated visit (may not be baseline)
text
C0429024 (UMLS CUI [1,1])
C0589121 (UMLS CUI [1,2])
ESP_EKG_HR
Item
HR interval from EKG at designated visit (may not be baseline)
text
C3846158 (UMLS CUI [1,1])
ESP_LVH_AT_EKG
Item
Left ventriculat hypertrophy status at baseline [0=No, 1=Yes]
text
C0149721 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
ESP_AFLUT_AT_EKG
Item
Atrial flutter at EKG
text
C0004239 (UMLS CUI [1,1])
ESP_WPW_AT_EKG
Item
Wolf-Parkinson-White pattern
text
C0043202 (UMLS CUI [1,1])
ESP_AVBLOCK2_AT_EKG
Item
Second degree AV block
text
C0264906 (UMLS CUI [1,1])
ESP_AVBLOCK3_AT_EKG
Item
Third degree AV block
text
C0151517 (UMLS CUI [1,1])
Item
Cornell voltage for EKG measurement, for EKG group.
text
C0428967 (UMLS CUI [1,1])
C0149721 (UMLS CUI [1,2])
ESP_CORNELL_VOLTAGE_EKG
Code List
Cornell voltage for EKG measurement, for EKG group.
CL Item
No (0)
CL Item
Yes (1)
Item
Pacer at EKG
text
C0030163 (UMLS CUI [1,1])
C0438154 (UMLS CUI [1,2])
ESP_PACER_EKG
Code List
Pacer at EKG
CL Item
No (0)
CL Item
Yes (1)
Item
Digoxin, for EKG group
text
C0012265 (UMLS CUI [1,1])
ESP_DIGOXIN_EKG
Code List
Digoxin, for EKG group
CL Item
No (0)
CL Item
Yes (1)
Item
Dihydropyridine calcium channel blockers
text
C2945601 (UMLS CUI [1,1])
ESP_DIHYDRO_CALCIUM_CHANNEL_BLOC
Code List
Dihydropyridine calcium channel blockers
CL Item
No (0)
CL Item
Yes (1)
Item
Non-dihydropyridine calcium channel blockers, for EKG group
text
C0006684 (UMLS CUI [1,1])
C0332300 (UMLS CUI [1,2])
C2945601 (UMLS CUI [1,3])
ESP_NONDIHYDRO_CALCIUM_CHANNEL_B
Code List
Non-dihydropyridine calcium channel blockers, for EKG group
CL Item
No (0)
CL Item
Yes (1)
Item
Any Calcium Channel blocker (only for ARIC - other HeartGO cohorts have this broken down by Dihydro versus Non-Dihydro)
text
C0006684 (UMLS CUI [1,1])
C1552551 (UMLS CUI [1,2])
ESP_CALCIUM_CHANNEL_BLOCKERS_EKG
Code List
Any Calcium Channel blocker (only for ARIC - other HeartGO cohorts have this broken down by Dihydro versus Non-Dihydro)
CL Item
No (0)
CL Item
Yes (1)
Item
Betablockers, for EKG group
text
C0001645 (UMLS CUI [1,1])
ESP_BETA_BLOCKERS_EKG
Code List
Betablockers, for EKG group
CL Item
No (0)
CL Item
Yes (1)
ESP_AGE_AT_EKG
Item
Age in years at EKG measurement
text
C1623258 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_SERUM_CYSTATINC
Item
Raw cystatin C (mg/L)
text
C1619716 (UMLS CUI [1,1])
ESP_AGE_AT_SERUM_CYSTATINC
Item
Age in years at serum cystatin c measurement
text
C1619716 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_URIC_ACID
Item
Uric acid in mg/dL
text
C0202239 (UMLS CUI [1,1])
ESP_AGE_AT_URIC_ACID
Item
Age in years at uric acid measurement
text
C0202239 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_URINARY_ALBUMIN
Item
Raw urinary albumin. Note: Users need to confirm units are the same across cohorts
text
C0587185 (UMLS CUI [1,1])
ESP_AGE_AT_URINARY_ALBUMIN
Item
Age in years at urinary albumin measurement
text
C1318429 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ESP_URINARY_CREATININE
Item
Raw urinary creatinine in mg/dL
text
C1318439 (UMLS CUI [1,1])
ESP_AGE_AT_URINARY_CREATININE
Item
Age in years at urinary creatinine measurement
text
C1318439 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
Item
May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study.
text
C0018099 (UMLS CUI [1,1])
ESP_GOUT
Code List
May be MD-reported, self-reported, or abstracted from patients taking allopurinol. Ever had gout through study.
CL Item
No (0)
CL Item
Yes (1)
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