ID
45270
Description
Principal Investigator: J. Dennis Fortenberry, Indiana University School of Medicine, Indianapolis, IN, USA MeSH: Genitalia, Male,Urethritis,Sexually Transmitted Diseases, Bacterial,Circumcision, Male,Dysuria,Prostatitis https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000259 Urethral microbiome of adolescent males is designed to characterize the microbial communities resident in the urethra of young men, to identify differences in these communities as a function of race/ethnicity, circumcision status, sexual exposures, and uro-genital symptoms. We collect detailed sexual behavior and symptoms data using cellular telephones with Internet access. Specimens are routinely collected at monthly intervals, and intermittently following reported symptoms, specific sexual exposures, or identification of a sexually transmitted infection. We also collect periodic samples from the penile coronal sulcus to better characterize its relationship to the urethral micriobial communities. Participants are ages 14 - 17 at enrollment, and prior history of sexual exposure is not required for participation. Parental permission is obtained for each participant. The planned duration of followup is up to 4 years allowing for prospective observation of both physical and behavioral maturation from middle adolescence into young adulthood. The overall objectives of the project are to better characterize the healthy male urethral microbiome, and to use this information to better understand acquisition of urethritis and sexually transmitted infections, as well as chronic genital pain and prostatitis syndromes that become common among young adults.
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Versions (3)
- 07/06/22 07/06/22 - Dr. Christian Niklas
- 07/06/22 07/06/22 - Dr. Christian Niklas
- 12/10/22 12/10/22 - Adrian Schulz
Détendeur de droits
J. Dennis Fortenberry
Téléchargé le
12 ottobre 2022
DOI
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Licence
Creative Commons BY 4.0
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dbGaP phs000259 Urethral Microbiome of Adolescent Males
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- HMP_Urethral_Males_Subject - Consent Group Information
- HMP_Urethral_Males_Sample - Subject Mapping
- The dataset describes participants' race/ethnicity, Tanner staging, circumcision status, and parents' educational status.
- The dataset describes presence/absence of sexually transmitted infections in participants, white blood cell count and time of data collection (in months).
- The dataset describes presence/absence and intensity of symptoms that may affect the uro-gential area (n=12 variables), how symptoms affect participants' life (n=3 variables), and time of data collection (in months).
- HMP_Urethral_Males_Sample - Trace Mapping
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- HMP_Urethral_Males_Subject - Consent Group Information
- HMP_Urethral_Males_Sample - Subject Mapping
- The dataset describes participants' race/ethnicity, Tanner staging, circumcision status, and parents' educational status.
- The dataset describes presence/absence of sexually transmitted infections in participants, white blood cell count and time of data collection (in months).
- The dataset describes presence/absence and intensity of symptoms that may affect the uro-gential area (n=12 variables), how symptoms affect participants' life (n=3 variables), and time of data collection (in months).
- HMP_Urethral_Males_Sample - Trace Mapping
C0680251 (UMLS CUI [1,2])
C0079399 (UMLS CUI [1,2])
C0376245 (UMLS CUI [1,2])
C1510558 (UMLS CUI [2,1])
C0037750 (UMLS CUI [2,2])
C1457887 (UMLS CUI [1,2])
C0011008 (UMLS CUI [1,3])
C0679646 (UMLS CUI [1,4])
C1516879 (UMLS CUI [1,5])
C0543467 (UMLS CUI [1,2])
C0587378 (UMLS CUI [1,3])
C0013227 (UMLS CUI [1,4])
C0008679 (UMLS CUI [1,5])
C0041967 (UMLS CUI [1,6])
C1514463 (UMLS CUI [2,1])
C0543467 (UMLS CUI [2,2])
C0587378 (UMLS CUI [2,3])
C0013227 (UMLS CUI [2,4])
C0008679 (UMLS CUI [2,5])
C0005682 (UMLS CUI [2,6])
C1514463 (UMLS CUI [3,1])
C0543467 (UMLS CUI [3,2])
C0587378 (UMLS CUI [3,3])
C0013227 (UMLS CUI [3,4])
C0008679 (UMLS CUI [3,5])
C0022646 (UMLS CUI [3,6])
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