ID

45228

Beschreibung

Principal Investigator: MeSH: Major Depressive Disorder https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000020 Identification of genomic regions that confer susceptibility to or protection from major depressive disorder (MDD) via genomewide association. *Consent groups and participant set* - Psychiatric and Related Somatic Conditions (PRSC): 3741 (1821 cases, 1822 controls, 98 others)

Link

dbGaP study = phs000020

Stichworte

  1. 26.07.22 26.07.22 - Martin Dugas
  2. 12.10.22 12.10.22 - Adrian Schulz
Rechteinhaber

Patrick F. Sullivan, University of North Carolina, Chapel Hill, NC, USA

Hochgeladen am

12. Oktober 2022

DOI

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Lizenz

Creative Commons BY 4.0

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dbGaP phs000020 Major Depression: Stage 1 Genomewide Association in Population-Based Samples

Eligibility Criteria

Inclusion and exclusion criteria
Beschreibung

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C0680252
MDD cases were recruited through mental health care organizations, general practices and in the community setting (for details see Boomsma et al. 2007; in press). The inclusion criteria for the 1780 participants are: 1) a DSM-IV diagnosis of major depressive disorder as confirmed by the CIDI psychiatric interview, 2) an age between 18 through 65 years, 3) sufficient knowledge of the Dutch language, and 4) North-european ancestry. As the samples should be representative of patients seen in different settings, there are few a priori exclusion criteria. Excluded patients are: 1) those with a primary diagnosis of psychosis, bipolar disorder, obsessive compulsive disorder, severe addiction disorder and 2) those with insufficient knowledge of the Dutch language.
Beschreibung

cases

Datentyp

boolean

Alias
UMLS CUI [1,1]
C3274647
For age and gender matched control subjects are mainly derived from the Netherlands Twin Register, for which data collection in twin, their parents, spouses and siblings occurred in 1991, 1993, 1995, 1997, 2000, 2002/3 and 2004/5. A total of 1860 controls were selected (only one member from each family) with the following inclusion criteria: 1) age 18 through 65 years, 2) never scoring high (> 0.65) on a general factor score for anxious depression (a combined measure of neuroticism, anxiety and depressive symptoms via questionnaires, Boomsma et al., 2000), 3) never reported a history of MDD in any survey, and 4) North-european ancestry. Controls and their parents were born in the Netherlands or northwestern Europe.
Beschreibung

controls

Datentyp

boolean

Alias
UMLS CUI [1,1]
C3274648

Ähnliche Modelle

Eligibility Criteria

Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
Inclusion and exclusion criteria
C0680252 (UMLS CUI [1,1])
cases
Item
MDD cases were recruited through mental health care organizations, general practices and in the community setting (for details see Boomsma et al. 2007; in press). The inclusion criteria for the 1780 participants are: 1) a DSM-IV diagnosis of major depressive disorder as confirmed by the CIDI psychiatric interview, 2) an age between 18 through 65 years, 3) sufficient knowledge of the Dutch language, and 4) North-european ancestry. As the samples should be representative of patients seen in different settings, there are few a priori exclusion criteria. Excluded patients are: 1) those with a primary diagnosis of psychosis, bipolar disorder, obsessive compulsive disorder, severe addiction disorder and 2) those with insufficient knowledge of the Dutch language.
boolean
C3274647 (UMLS CUI [1,1])
controls
Item
For age and gender matched control subjects are mainly derived from the Netherlands Twin Register, for which data collection in twin, their parents, spouses and siblings occurred in 1991, 1993, 1995, 1997, 2000, 2002/3 and 2004/5. A total of 1860 controls were selected (only one member from each family) with the following inclusion criteria: 1) age 18 through 65 years, 2) never scoring high (> 0.65) on a general factor score for anxious depression (a combined measure of neuroticism, anxiety and depressive symptoms via questionnaires, Boomsma et al., 2000), 3) never reported a history of MDD in any survey, and 4) North-european ancestry. Controls and their parents were born in the Netherlands or northwestern Europe.
boolean
C3274648 (UMLS CUI [1,1])

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