ID

45219

Descripción

Principal Investigator: Kari Stefansson, MD, PhD, deCODE Genetics, Inc., Reykjavik, Iceland MeSH: Tobacco Use Disorder https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000393 A genome-wide association study on smoking behavior and nicotine dependence in Icelandic smokers, assessed by the number of cigarettes smoked per day, smoking initiation and degree of dependence on nicotine. The number of cigarettes smoked per day was ascertained through questionnaires given to individuals participating in multiple disease projects at deCODE Genetics (n=16,483). Smoking initiation was analyzed by comparing those that have ever smoked (n=16,483) versus those that have never smoked (n=21,667). The nicotine dependence analysis included 3,435 nicotine dependent cases (score 4 or higher on Fagerstrom Test for Nicotine Dependence (FTND) or endorsement of at least three of the seven Diagnostic and Statistical Manual of Mental Disorders 4th edition (DSM-IV) criteria) and 3,344 low-quantity smokers as controls.

Link

dbGaP study = phs000393

Palabras clave

  1. 31/7/22 31/7/22 - Simon Heim
  2. 12/10/22 12/10/22 - Adrian Schulz
Titular de derechos de autor

Kari Stefansson, MD, PhD, deCODE Genetics, Inc., Reykjavik, Iceland

Subido en

12 de octubre de 2022

DOI

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Licencia

Creative Commons BY 4.0

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dbGaP phs000393 Genes Contributing to Nicotine Dependence in Humans

Eligibility Criteria

Inclusion and exclusion criteria
Descripción

Inclusion and exclusion criteria

Individuals showing low genotype yield were excluded from the analysis (<98% call rate).
Descripción

Individuals showing low genotype yield were excluded from the analysis (<98% call rate).

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0680251
UMLS CUI [1,2]
C1285573

Similar models

Eligibility Criteria

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
Inclusion and exclusion criteria
Individuals showing low genotype yield were excluded from the analysis (<98% call rate).
Item
Individuals showing low genotype yield were excluded from the analysis (<98% call rate).
boolean
C0680251 (UMLS CUI [1,1])
C1285573 (UMLS CUI [1,2])

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