ID
45207
Beschreibung
Principal Investigator: David Carey, PhD, Weis Center for Research, Geisinger Clinic, Danville, PA, USA MeSH: Abdominal Aortic Aneurysms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000387 A large research cohort of Geisinger Abdominal Aortic Aneurysm (AAA) patients was created by enrolling and consenting patients of the Geisinger Department of Vascular Surgery. Consented patients provide blood, serum and DNA samples for research and authorize use of data in their medical record for research. They also complete a data questionnaire that asks information about family history of AAA and other vascular diseases, as well as information on known or suspected AAA risk factors, including smoking history, body mass index, hypertension, type 2 diabetes, and atherosclerotic disease. The AAA cases are 78% male, with a mean age of 74 years; 39% have undergone surgical or endovascular repair; more than 85% or current or past smokers; approximately 20% of cases report a positive family history of AAA. Geisinger AAA patients undergo regular imaging studies, typically every 6 months, to monitor the progression of aneurysm expansion. This allows the growth rates of their aneurysm to be calculated. DNA samples from a total of 910 AAA patients were used for whole genome genotyping; these results are included in the dbGaP.
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Versionen (2)
- 04.08.22 04.08.22 - Simon Heim
- 12.10.22 12.10.22 - Adrian Schulz
Rechteinhaber
David Carey, PhD, Weis Center for Research, Geisinger Clinic, Danville, PA, USA
Hochgeladen am
12. Oktober 2022
DOI
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Lizenz
Creative Commons BY 4.0
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dbGaP phs000387 Geisinger eMERGE - Abdominal Aortic Aneurysm Project (AAAP)
Subject - Consent Information
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent Information
- Subject - Sample - Mapping
- The dataset provides medical backgroud information regarding diagnoses of: abdominal aortic aneurysm, peripheral aortic disease, arterial dissection; blood pressure measurements, and wether or not subjects had undergone bariatric surgery. Data of weight/height and use of tobacco and alcohol, and general socio-demographic information is also provided. All subjects have been diagnosed with abdominal aortic aneurysm (cases).
- Sample - Attribute Information (analyte type, body area that is the source etc.).
Ähnliche Modelle
Subject - Consent Information
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent Information
- Subject - Sample - Mapping
- The dataset provides medical backgroud information regarding diagnoses of: abdominal aortic aneurysm, peripheral aortic disease, arterial dissection; blood pressure measurements, and wether or not subjects had undergone bariatric surgery. Data of weight/height and use of tobacco and alcohol, and general socio-demographic information is also provided. All subjects have been diagnosed with abdominal aortic aneurysm (cases).
- Sample - Attribute Information (analyte type, body area that is the source etc.).
C3847505 (UMLS CUI [1,2])
C0449416 (UMLS CUI [1,2])
C3847505 (UMLS CUI [1,3])