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ID

45182

Description

Principal Investigator: Mark Purdue, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MD, USA MeSH: Carcinoma, Renal Cell,Kidney Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000351 The National Cancer Institute (NCI) genome-wide association study (GWAS) of renal cell carcinoma (RCC) was conducted to investigate common genetic variants associated with RCC risk. The GWAS includes 1,453 RCC cases and 3,531 controls of European background from 4 studies (3 cohort, 1 case-control), scanned using the Illumina InfiniumHumanHap 550, 610 and 660W chips. This project was supported by the Intramural Research Program of the National Institutes of Health and NCI. Data from this GWAS were pooled with those from another GWAS of RCC (2,639 cases and 5,392 controls) conducted in Europe by the International Agency for Research on Cancer and the Centre National de Gènotypage. Findings from this collaboration are described in an upcoming report (Purdue et al. Nature Genetics 2011;43(1):60-65; PMID: 21131975). Only data from the NCI scan are included in this dbGaP submission.

Link

dbGaP study = phs000351

Keywords

  1. 8/20/22 8/20/22 - Simon Heim
  2. 10/12/22 10/12/22 - Adrian Schulz
Copyright Holder

Mark Purdue, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MD, USA

Uploaded on

October 12, 2022

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Creative Commons BY 4.0

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    dbGaP phs000351 NCI Genome-Wide Association Study of Renal Cell Carcinoma

    Eligibility Criteria

    Inclusion and exclusion criteria
    Description

    Inclusion and exclusion criteria

    Inclusion criteria:
    Description

    Inclusion criteria

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C1512693
    Non-Hispanic Caucasian race
    Description

    Non-Hispanic Caucasian race

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C1512693
    UMLS CUI [1,2]
    C1518424
    UMLS CUI [1,3]
    C0043157
    Adequate consent for GWAS
    Description

    Adequate consent for GWAS

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C1512693
    UMLS CUI [1,2]
    C0021430
    Cases: diagnosis of pathologically confirmed renal cancer (International Classification of Diseases for Oncology, Second Edition, Topography C64).
    Description

    Cases: diagnosis of pathologically confirmed renal cancer (International Classification of Diseases for Oncology, Second Edition, Topography C64).

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C1706256
    UMLS CUI [1,2]
    C1271092
    UMLS CUI [1,3]
    C0740457

    Similar models

    Eligibility Criteria

    Name
    Type
    Description | Question | Decode (Coded Value)
    Data type
    Alias
    Item Group
    Inclusion and exclusion criteria
    Inclusion criteria
    Item
    Inclusion criteria:
    boolean
    C1512693 (UMLS CUI [1,1])
    Non-Hispanic Caucasian race
    Item
    Non-Hispanic Caucasian race
    boolean
    C1512693 (UMLS CUI [1,1])
    C1518424 (UMLS CUI [1,2])
    C0043157 (UMLS CUI [1,3])
    Adequate consent for GWAS
    Item
    Adequate consent for GWAS
    boolean
    C1512693 (UMLS CUI [1,1])
    C0021430 (UMLS CUI [1,2])
    Cases: diagnosis of pathologically confirmed renal cancer (International Classification of Diseases for Oncology, Second Edition, Topography C64).
    Item
    Cases: diagnosis of pathologically confirmed renal cancer (International Classification of Diseases for Oncology, Second Edition, Topography C64).
    boolean
    C1706256 (UMLS CUI [1,1])
    C1271092 (UMLS CUI [1,2])
    C0740457 (UMLS CUI [1,3])

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