ID
45167
Description
Principal Investigator: Joel Gelernter, MD, Yale University School of Medicine, New Haven, CT, USA MeSH: Alcoholism,Cocaine Dependence,Nicotine Dependence,Opiate Dependence https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000425 This study includes SSADDA (Semi Structured Assessment for Drug Dependence and Alcoholism) assessed subjects (mostly unrelated, but including some affected sibling pairs) recruited in the course of several substance dependence genetics projects. The sample includes 1889 African-American (AA) subjects and 1020 European-American (EA) subjects. Among the AAs, 1397 meet DSM-IV criteria for alcohol dependence and 491 are controls. Among the EAs, 1010 meet the criteria for alcohol dependence and 9 are controls. (One in each population meets criteria for alcohol abuse and not dependence, and is therefore counted in neither category.) Although alcohol dependence is the major focus, the sample is informative also for cocaine, nicotine, and opioid dependence.
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Versions (3)
- 8/23/22 8/23/22 - Niko Möller-Grell
- 10/12/22 10/12/22 - Adrian Schulz
- 1/29/25 1/29/25 - Akane Nishihara
Copyright Holder
Joel Gelernter, MD, Yale University School of Medicine, New Haven, CT, USA
Uploaded on
October 12, 2022
DOI
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License
Creative Commons BY 4.0
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dbGaP phs000425 Alcohol Dependence GWAS in European- and African Americans
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent Information
- Subject - Sample Mapping
- The dataset contains data that were obtained through the 'Semi Structured Assessment for Drug Dependence and Alcoholism' questionnaire, and assess presence/absence of Alcohol (and other) dependencies, phobias, and other psychiatric conditions, including: Attention-Deficit/Hyperactivity Disorder, agoraphobia, schizophrenia, generalized anxiety disorder, etc. (n=24 variables). Alcohol dependence is described through n=7 addiction variables, assessing tolerance, withrawl, physical/psychological dependies. Basic socio-demographic data are included as well (i.e. variables gender/age/race).
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject - Consent Information
- Subject - Sample Mapping
- The dataset contains data that were obtained through the 'Semi Structured Assessment for Drug Dependence and Alcoholism' questionnaire, and assess presence/absence of Alcohol (and other) dependencies, phobias, and other psychiatric conditions, including: Attention-Deficit/Hyperactivity Disorder, agoraphobia, schizophrenia, generalized anxiety disorder, etc. (n=24 variables). Alcohol dependence is described through n=7 addiction variables, assessing tolerance, withrawl, physical/psychological dependies. Basic socio-demographic data are included as well (i.e. variables gender/age/race).
C0001973 (UMLS CUI [1,2])
C0680251 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
C0005586 (UMLS CUI [2,3])
C4534351 (UMLS CUI [2,4])
C3554639 (UMLS CUI [2,5])