ID

45165

Beskrivning

Principal Investigator: Andrzej Krolewski, MD, PhD, Joslin Diabetes Center, Boston, MA, USA MeSH: Diabetic Nephropathies https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000302 A collection of patients with type-2 diabetes was collected at the Joslin Diabetes Center. Patients were categorized to a group of cases with diabetic nephropathy, and a group of controls with normoalbuminuria. From these groups, 173 cases and 177 controls were randomly selected for a genome-wide association study.

Länk

dbGaP study = phs000302

Nyckelord

  1. 2022-08-25 2022-08-25 - Chiara Middel
  2. 2022-10-12 2022-10-12 - Adrian Schulz
Rättsinnehavare

Andrzej Krolewski, MD, PhD, Joslin Diabetes Center, Boston, MA, USA

Uppladdad den

12 oktober 2022

DOI

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Licens

Creative Commons BY 4.0

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dbGaP phs000302 Genetic Study on Nephropathy in Type-2 Diabetes

Eligibility Criteria

Inclusion and exclusion criteria
Beskrivning

Inclusion and exclusion criteria

*Inclusion as Participant:*
Beskrivning

Elig.phs000302.v1.p1.1

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1512693
Self-reported diabetes mellitus (DM)
Beskrivning

Elig.phs000302.v1.p1.2

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0011849
UMLS CUI [1,2]
C2700446
Age at diagnosis of DM greater than 40, or age at diagnosis between 20 and 40 and no insulin treatment, or age at diagnosis between 20 and 40 and initiation of insulin treatment more than 2 years after diagnosis of DM
Beskrivning

Elig.phs000302.v1.p1.3

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1828181
UMLS CUI [2,1]
C1828181
UMLS CUI [2,2]
C1298908
UMLS CUI [2,3]
C0745343
UMLS CUI [3,1]
C1828181
UMLS CUI [3,2]
C0205087
UMLS CUI [3,3]
C1704686
UMLS CUI [3,4]
C0745343
Absence of non-diabetic kidney disease
Beskrivning

Elig.phs000302.v1.p1.4

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0332197
UMLS CUI [1,2]
C0022658
*Inclusion as Control:*
Beskrivning

Elig.phs000302.v1.p1.5

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0009932
Normoalbuminuria
Beskrivning

Elig.phs000302.v1.p1.6

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0001925
UMLS CUI [1,2]
C0205307
CKD Stage 1 or 2
Beskrivning

Elig.phs000302.v1.p1.7

Datatyp

boolean

Alias
UMLS CUI [1,1]
C2316401
UMLS CUI [1,2]
C2316786
Duration of DM of at least 3 years
Beskrivning

Elig.phs000302.v1.p1.8

Datatyp

boolean

Alias
UMLS CUI [1,1]
C2926735
UMLS CUI [1,2]
C0011849
Hemoglobin A1c of at least 6
Beskrivning

Elig.phs000302.v1.p1.9

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0474680
*Inclusion as Case:*
Beskrivning

Elig.phs000302.v1.p1.10

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C1698493
Proteinuria or End-Stage Renal Disease or Microalbuminuria and CKD Stage 4 or 5
Beskrivning

Elig.phs000302.v1.p1.11

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0033687
UMLS CUI [2,1]
C0854078
UMLS CUI [3,1]
C0730345
UMLS CUI [4,1]
C2317473
UMLS CUI [4,2]
C2316810

Similar models

Eligibility Criteria

Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
Inclusion and exclusion criteria
Elig.phs000302.v1.p1.1
Item
*Inclusion as Participant:*
boolean
C1512693 (UMLS CUI [1,1])
Elig.phs000302.v1.p1.2
Item
Self-reported diabetes mellitus (DM)
boolean
C0011849 (UMLS CUI [1,1])
C2700446 (UMLS CUI [1,2])
Elig.phs000302.v1.p1.3
Item
Age at diagnosis of DM greater than 40, or age at diagnosis between 20 and 40 and no insulin treatment, or age at diagnosis between 20 and 40 and initiation of insulin treatment more than 2 years after diagnosis of DM
boolean
C1828181 (UMLS CUI [1,1])
C1828181 (UMLS CUI [2,1])
C1298908 (UMLS CUI [2,2])
C0745343 (UMLS CUI [2,3])
C1828181 (UMLS CUI [3,1])
C0205087 (UMLS CUI [3,2])
C1704686 (UMLS CUI [3,3])
C0745343 (UMLS CUI [3,4])
Elig.phs000302.v1.p1.4
Item
Absence of non-diabetic kidney disease
boolean
C0332197 (UMLS CUI [1,1])
C0022658 (UMLS CUI [1,2])
Elig.phs000302.v1.p1.5
Item
*Inclusion as Control:*
boolean
C1512693 (UMLS CUI [1,1])
C0009932 (UMLS CUI [1,2])
Elig.phs000302.v1.p1.6
Item
Normoalbuminuria
boolean
C0001925 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Elig.phs000302.v1.p1.7
Item
CKD Stage 1 or 2
boolean
C2316401 (UMLS CUI [1,1])
C2316786 (UMLS CUI [1,2])
Elig.phs000302.v1.p1.8
Item
Duration of DM of at least 3 years
boolean
C2926735 (UMLS CUI [1,1])
C0011849 (UMLS CUI [1,2])
Elig.phs000302.v1.p1.9
Item
Hemoglobin A1c of at least 6
boolean
C0474680 (UMLS CUI [1,1])
Elig.phs000302.v1.p1.10
Item
*Inclusion as Case:*
boolean
C1512693 (UMLS CUI [1,1])
C1698493 (UMLS CUI [1,2])
Elig.phs000302.v1.p1.11
Item
Proteinuria or End-Stage Renal Disease or Microalbuminuria and CKD Stage 4 or 5
boolean
C0033687 (UMLS CUI [1,1])
C0854078 (UMLS CUI [2,1])
C0730345 (UMLS CUI [3,1])
C2317473 (UMLS CUI [4,1])
C2316810 (UMLS CUI [4,2])

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