ID

45104

Beskrivning

Principal Investigator: Joel Gelernter, MD, Yale University School of Medicine, New Haven, CT, USA MeSH: Alcoholism,Cocaine Dependence,Nicotine Dependence,Opiate Dependence https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000425 This study includes SSADDA (Semi Structured Assessment for Drug Dependence and Alcoholism) assessed subjects (mostly unrelated, but including some affected sibling pairs) recruited in the course of several substance dependence genetics projects. The sample includes 1889 African-American (AA) subjects and 1020 European-American (EA) subjects. Among the AAs, 1397 meet DSM-IV criteria for alcohol dependence and 491 are controls. Among the EAs, 1010 meet the criteria for alcohol dependence and 9 are controls. (One in each population meets criteria for alcohol abuse and not dependence, and is therefore counted in neither category.) Although alcohol dependence is the major focus, the sample is informative also for cocaine, nicotine, and opioid dependence.

Länk

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000425

Nyckelord

  1. 2022-08-23 2022-08-23 - Niko Möller-Grell
  2. 2022-10-12 2022-10-12 - Adrian Schulz
  3. 2025-01-29 2025-01-29 - Akane Nishihara
Rättsinnehavare

Joel Gelernter, MD, Yale University School of Medicine, New Haven, CT, USA

Uppladdad den

23 augusti 2022

DOI

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Licens

Creative Commons BY 4.0

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dbGaP phs000425 Alcohol Dependence GWAS in European- and African Americans

Eligibility Criteria

Inclusion and exclusion criteria
Beskrivning

Inclusion and exclusion criteria

Affected subjects were included on the basis of meeting DSM-IV criteria for alcohol dependence. Schizophrenia, bipolar affective disorder, or other major psychotic illness and gross cognitive impairment were exclusion criteria.
Beskrivning

Elig.phs000425.v1.p1.1

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0001973
UMLS CUI [2,1]
C0680251
UMLS CUI [2,2]
C0036341
UMLS CUI [2,3]
C0005586
UMLS CUI [2,4]
C4534351
UMLS CUI [2,5]
C3554639

Similar models

Eligibility Criteria

Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
Inclusion and exclusion criteria
Elig.phs000425.v1.p1.1
Item
Affected subjects were included on the basis of meeting DSM-IV criteria for alcohol dependence. Schizophrenia, bipolar affective disorder, or other major psychotic illness and gross cognitive impairment were exclusion criteria.
boolean
C1512693 (UMLS CUI [1,1])
C0001973 (UMLS CUI [1,2])
C0680251 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
C0005586 (UMLS CUI [2,3])
C4534351 (UMLS CUI [2,4])
C3554639 (UMLS CUI [2,5])

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