ID

45104

Beschreibung

Principal Investigator: Joel Gelernter, MD, Yale University School of Medicine, New Haven, CT, USA MeSH: Alcoholism,Cocaine Dependence,Nicotine Dependence,Opiate Dependence https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000425 This study includes SSADDA (Semi Structured Assessment for Drug Dependence and Alcoholism) assessed subjects (mostly unrelated, but including some affected sibling pairs) recruited in the course of several substance dependence genetics projects. The sample includes 1889 African-American (AA) subjects and 1020 European-American (EA) subjects. Among the AAs, 1397 meet DSM-IV criteria for alcohol dependence and 491 are controls. Among the EAs, 1010 meet the criteria for alcohol dependence and 9 are controls. (One in each population meets criteria for alcohol abuse and not dependence, and is therefore counted in neither category.) Although alcohol dependence is the major focus, the sample is informative also for cocaine, nicotine, and opioid dependence.

Link

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000425

Stichworte

  1. 23.08.22 23.08.22 - Niko Möller-Grell
  2. 12.10.22 12.10.22 - Adrian Schulz
  3. 29.01.25 29.01.25 - Akane Nishihara
Rechteinhaber

Joel Gelernter, MD, Yale University School of Medicine, New Haven, CT, USA

Hochgeladen am

23. August 2022

DOI

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Lizenz

Creative Commons BY 4.0

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dbGaP phs000425 Alcohol Dependence GWAS in European- and African Americans

Eligibility Criteria

Inclusion and exclusion criteria
Beschreibung

Inclusion and exclusion criteria

Affected subjects were included on the basis of meeting DSM-IV criteria for alcohol dependence. Schizophrenia, bipolar affective disorder, or other major psychotic illness and gross cognitive impairment were exclusion criteria.
Beschreibung

Elig.phs000425.v1.p1.1

Datentyp

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0001973
UMLS CUI [2,1]
C0680251
UMLS CUI [2,2]
C0036341
UMLS CUI [2,3]
C0005586
UMLS CUI [2,4]
C4534351
UMLS CUI [2,5]
C3554639

Ähnliche Modelle

Eligibility Criteria

Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
Inclusion and exclusion criteria
Elig.phs000425.v1.p1.1
Item
Affected subjects were included on the basis of meeting DSM-IV criteria for alcohol dependence. Schizophrenia, bipolar affective disorder, or other major psychotic illness and gross cognitive impairment were exclusion criteria.
boolean
C1512693 (UMLS CUI [1,1])
C0001973 (UMLS CUI [1,2])
C0680251 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
C0005586 (UMLS CUI [2,3])
C4534351 (UMLS CUI [2,4])
C3554639 (UMLS CUI [2,5])

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