ID

45076

Beskrivning

Principal Investigator: Steven R. Brant, MD, Johns Hopkins University, Baltimore, MD, USA MeSH: Crohn Disease,Colitis, Ulcerative,Inflammatory Bowel Diseases https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000367 The National Institute of Diabetes and Digestive and Kidney Diseases Inflammatory Bowel Disease Genetics Consortium (NIDDK - IBDGC) conducted a genome wide association study (GWAS) using the Human Omni2.5-Quad beadchip from Illumina to identify disease variants associated with familial Crohn's disease. This study includes a subset of individuals from an original cohort of affected subjects and affected/unaffected relatives from a previous linkage scan which showed increased linkage evidence at three novel risk loci. A total of 708 samples were selected based on various criteria for inclusion from the 6 Genetic Research Centers (GRC) in North America that participate in the IBDGC. This project was supported by an ancillary R01 grant from the NIDDK with resources made available through the IBDGC.

Länk

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000367

Nyckelord

  1. 2022-08-19 2022-08-19 - Simon Heim
  2. 2022-10-12 2022-10-12 - Adrian Schulz
Rättsinnehavare

Steven R. Brant, MD, Johns Hopkins University, Baltimore, MD, USA

Uppladdad den

19 augusti 2022

DOI

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Licens

Creative Commons BY 4.0

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dbGaP phs000367 Genome Wide Association Study in Familial Crohn's Disease

Eligibility Criteria

Inclusion and exclusion criteria
Beskrivning

Inclusion and exclusion criteria

Inclusion Criteria:
Beskrivning

Inclusion Criteria

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1512693
Proper consent and IRB approval for release of data to dbGaP
Beskrivning

Proper consent and IRB approval for release of data to dbGaP

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0021430
Non-Hispanic Caucasian
Beskrivning

Non-Hispanic Caucasian

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C1518424
UMLS CUI [1,3]
C0043157
Confirm diagnosis of IBD and relatives/family members
Beskrivning

Confirm diagnosis of IBD and relatives/family members

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0011900
UMLS CUI [1,2]
C0022104
UMLS CUI [1,3]
C0086282

Similar models

Eligibility Criteria

Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
Inclusion and exclusion criteria
Inclusion Criteria
Item
Inclusion Criteria:
boolean
C1512693 (UMLS CUI [1,1])
Proper consent and IRB approval for release of data to dbGaP
Item
Proper consent and IRB approval for release of data to dbGaP
boolean
C1512693 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
Non-Hispanic Caucasian
Item
Non-Hispanic Caucasian
boolean
C1512693 (UMLS CUI [1,1])
C1518424 (UMLS CUI [1,2])
C0043157 (UMLS CUI [1,3])
Confirm diagnosis of IBD and relatives/family members
Item
Confirm diagnosis of IBD and relatives/family members
boolean
C0011900 (UMLS CUI [1,1])
C0022104 (UMLS CUI [1,2])
C0086282 (UMLS CUI [1,3])

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