ID

45041

Beschrijving

Principal Investigator: Kari Stefansson, MD, PhD, deCODE Genetics, Inc., Reykjavik, Iceland MeSH: Tobacco Use Disorder https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000393 A genome-wide association study on smoking behavior and nicotine dependence in Icelandic smokers, assessed by the number of cigarettes smoked per day, smoking initiation and degree of dependence on nicotine. The number of cigarettes smoked per day was ascertained through questionnaires given to individuals participating in multiple disease projects at deCODE Genetics (n=16,483). Smoking initiation was analyzed by comparing those that have ever smoked (n=16,483) versus those that have never smoked (n=21,667). The nicotine dependence analysis included 3,435 nicotine dependent cases (score 4 or higher on Fagerstrom Test for Nicotine Dependence (FTND) or endorsement of at least three of the seven Diagnostic and Statistical Manual of Mental Disorders 4th edition (DSM-IV) criteria) and 3,344 low-quantity smokers as controls.

Link

https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000393

Trefwoorden

  1. 31-07-22 31-07-22 - Simon Heim
  2. 12-10-22 12-10-22 - Adrian Schulz
Houder van rechten

Kari Stefansson, MD, PhD, deCODE Genetics, Inc., Reykjavik, Iceland

Geüploaded op

31 juli 2022

DOI

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Licentie

Creative Commons BY 4.0

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dbGaP phs000393 Genes Contributing to Nicotine Dependence in Humans

Eligibility Criteria

Inclusion and exclusion criteria
Beschrijving

Inclusion and exclusion criteria

Individuals showing low genotype yield were excluded from the analysis (<98% call rate).
Beschrijving

Individuals showing low genotype yield were excluded from the analysis (<98% call rate).

Datatype

boolean

Alias
UMLS CUI [1,1]
C0680251
UMLS CUI [1,2]
C1285573

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Inclusion and exclusion criteria
Individuals showing low genotype yield were excluded from the analysis (<98% call rate).
Item
Individuals showing low genotype yield were excluded from the analysis (<98% call rate).
boolean
C0680251 (UMLS CUI [1,1])
C1285573 (UMLS CUI [1,2])

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