ID
45026
Beschrijving
Principal Investigator: Donna Arnett, PhD, University of Alabama at Birmingham, Birmingham, AL, USA MeSH: Hypertension,Antihypertensive Agents,Drug Resistance https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000442 Resistant hypertension is defined as blood pressure that remains above goal in spite of the concurrent use of 3 antihypertensive agents of different classes or the concurrent use of 4 or more antihypertensive agents regardless of control. Its diagnosis is important for the identification of patients who are at high risk of having reversible causes of hypertension and/or patients who, because of persistently high blood pressure levels, may benefit from special diagnostic and therapeutic considerations. Resistant hypertension represents an extreme phenotype, thus, it has been predicted that genetic factors could play a larger role than for the general hypertensive population. Genetic assessments of patients with resistant hypertension have been limited. The current study assayed the exome of 91 African American patients with treatment resistant hypertension.
Link
https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000442
Trefwoorden
Versies (2)
- 22/07/22 22/07/22 - Chiara Middel
- 12/10/22 12/10/22 - Adrian Schulz
Houder van rechten
Donna Arnett, PhD, University of Alabama at Birmingham, Birmingham, AL, USA
Geüploaded op
22 luglio 2022
DOI
Voor een aanvraag inloggen.
Licentie
Creative Commons BY 4.0
Model Commentaren :
Hier kunt u commentaar leveren op het model. U kunt de tekstballonnen bij de itemgroepen en items gebruiken om er specifiek commentaar op te geven.
Itemgroep Commentaren voor :
Item Commentaren voor :
U moet ingelogd zijn om formulieren te downloaden. AUB inloggen of schrijf u gratis in.
dbGaP phs000442 Drug Resistant Hypertension in African Americans' Exome
Eligibility Criteria
Similar models
Eligibility Criteria
C0680251 (UMLS CUI [1,2])
C0332325 (UMLS CUI [1,2])
C0020538 (UMLS CUI [1,3])
C0003364 (UMLS CUI [1,4])
C1265611 (UMLS CUI [1,5])
C0031437 (UMLS CUI [2,1])
C0332325 (UMLS CUI [2,2])
C0020538 (UMLS CUI [2,3])