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44481
Beschrijving
A toplist of 150 medical concepts was created by collecting and annotating AML-specific documentation of different sources and contexts.
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Versies (2)
- 19-01-18 19-01-18 -
- 27-09-21 27-09-21 -
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C. Holz
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27 september 2021
DOI
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Creative Commons BY-NC-ND 3.0
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Top 150 Medical concepts in Acute myeloid leukemia (AML)
Collection of concepts
- StudyEvent: ODM
Similar models
Collection of concepts
- StudyEvent: ODM
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item
Disease Response/Remission Status
text
C1704632 (UMLS CUI [1])
CL Item
CR with incomplete recovery (CRi) [with date] (CR with incomplete recovery (CRi) [with date])
CL Item
Cytogenic CR (CRc) [with date] (Cytogenic CR (CRc) [with date])
CL Item
Death [with date] (Death [with date])
CL Item
Molecular CR (CRm) [with date] (Molecular CR (CRm) [with date])
CL Item
Morphologic leukemia- free state [with date] (Morphologic leukemia- free state [with date])
CL Item
Partial Remission [with date] (Partial Remission [with date])
CL Item
Progression [with date] (Progression [with date])
CL Item
Relapse [with date] (Relapse [with date])
CL Item
Resistant disease (RD) [with date] (Resistant disease (RD) [with date])
CL Item
Suggested Minimum Value Set: Complete remission (CR) [with date] (Suggested Minimum Value Set: Complete remission (CR) [with date])
Patient ID
Item
text
C2348585 (UMLS CUI [1])
Patient Date of Birth
Item
text
C0421451 (UMLS CUI [1])
CL Item
WHO-Classification (WHO-Classification)
CL Item
FAB-Classification (FAB-Classification)
CL Item
Date of diagnosis (Date of diagnosis)
CL Item
First diagnosis (First diagnosis)
Treatment
Item
text
C0087111 (UMLS CUI [1])
CL Item
Karnofsky index (Karnofsky index)
CL Item
ECOG performance status (ECOG performance status)
CL Item
Comorbidity Index (Comorbidity Index)
CL Item
Other hematological disease (Other hematological disease)
CL Item
Secondary AML after MDS (Secondary AML after MDS)
CL Item
Adverse event term CTCAE (Adverse event term CTCAE)
CL Item
Adverse event outcome (Adverse event outcome)
CL Item
Adverse event grade (Adverse event grade)
CL Item
Previous tumor disease in history (Previous tumor disease in history)
CL Item
Preexisting solid tumor (chemotherapy required) (Preexisting solid tumor (chemotherapy required))
CL Item
Secondary malignancy (Secondary malignancy)
CL Item
Second primary malignancy (Second primary malignancy)
CL Item
Complications (Complications)
CL Item
Chimerism (Chimerism)
CL Item
Relation to donor (Relation to donor)
CL Item
Source of stem cells (Source of stem cells)
CL Item
Allogeneic stem cell transplant (Allogeneic stem cell transplant)
CL Item
Autologous stem cell transplant (Autologous stem cell transplant)
CL Item
male (male)
CL Item
female (female)
Patient name
Item
text
C1299487 (UMLS CUI [1])
Extramedullary Manifestation
Item
text
C1868812 (UMLS CUI [1])
Patient personal data
Item
text
C2707520 (UMLS CUI [1])
Blasts
Item
integer
C1982687 (UMLS CUI [1])
Bilirubin
Item
float
C0201913 (UMLS CUI [1])
CL Item
Bone marrow puncture (Bone marrow puncture)
CL Item
Bone marrow sample (Bone marrow sample)
CL Item
Bone marrow sampling date (Bone marrow sampling date)
CL Item
Bone marrow examination possible (Bone marrow examination possible)
Platelets
Item
float
C0005821 (UMLS CUI [1])
Diagnosis date
Item
text
C2316983 (UMLS CUI [1])
Cytogenetics
Item
text
C0010802 (UMLS CUI [1])
CL Item
alive (alive)
CL Item
dead (dead)
CL Item
unknown(lost to follow-up) (unknown(lost to follow-up))
Chemotherapy Cycle
Item
text
C1302181 (UMLS CUI [1])
White blood count / Leukocytes
Item
float
C0023508 (UMLS CUI [1])
Hospital ID
Item
text
C2825164 (UMLS CUI [1])
CL Item
Date of engraftment (Date of engraftment)
CL Item
Platelets self-sustaining (Platelets self-sustaining)
CL Item
Platelets > x mg/dL (Platelets > x mg/dL)
Pregnancy
Item
boolean
C0032961 (UMLS CUI [1])
Drug Toxicity
Item
text
C0013221 (UMLS CUI [1])
Monocytes
Item
float
C0942447 (UMLS CUI [1])
ALAT/GPT
Item
float
C0201836 (UMLS CUI [1])
CL Item
A (A)
CL Item
B (B)
CL Item
AB (AB)
CL Item
0 (0)
CL Item
Year of chemotherapy/radiotherapy (Year of chemotherapy/radiotherapy)
CL Item
Chemotherapy medication (Chemotherapy medication)
CL Item
Radiotherapy specification (Radiotherapy specification)
CL Item
Date of engraftment (Date of engraftment)
CL Item
Neutrophil self-sustaining (Neutrophil self-sustaining)
CL Item
Neutrophils > x mg/dL at day (Neutrophils > x mg/dL at day)
Concomitant Medication
Item
text
C2347852 (UMLS CUI [1])
Serum creatinine
Item
float
C0201976 (UMLS CUI [1])
Lymphocytes
Item
float
CL Item
Number of CD34 cells infused (Number of CD34 cells infused)
CL Item
Determination of CD34 positivity (Determination of CD34 positivity)
CMV positivity
Item
boolean
C0582172 (UMLS CUI [1])
Date of previous contact
Item
date
C0805839 (UMLS CUI [1])
Informed consent signed
Item
boolean
C0021430 (UMLS CUI [1])
De novo AML indicator
Item
boolean
C0023467 (UMLS CUI [1])
Cause of Death
Item
text
C0007465 (UMLS CUI [1])
Auer Rods
Item
boolean
C0333828 (UMLS CUI [1])
Clusters of Blasts
Item
boolean
C0368761 (UMLS CUI [1])
LDH
Item
float
C0202113 (UMLS CUI [1])
INR/Quick
Item
float
Hb
Item
float
C0019046 (UMLS CUI [1])
Chemotherapy Regimen
Item
text
C0392920 (UMLS CUI [1])
EBV positivity
Item
boolean
C0014644 (UMLS CUI [1])
Karyotype
Item
text
C1261273 (UMLS CUI [1])
Follow-up
Item
text
C1522577 (UMLS CUI [1])
Patient Height
Item
float
C0005890 (UMLS CUI [1])
CL Item
Systolic blood pressure (1)
CL Item
Diastolic blood pressure (2)
Eosinophils
Item
float
C0945354 (UMLS CUI [1])
CL Item
aGvHD (aGvHD)
CL Item
cGvHD (cGvHD)
CL Item
GvHD Prophylaxis (GvHD Prophylaxis)
CL Item
GvHD medication (GvHD medication)
CL Item
GvHD stage (GvHD stage)
CL Item
GvHD start date (GvHD start date)
Pulse/Heart Rate
Item
integer
C0018810 (UMLS CUI [1])
CL Item
M0 (M0)
CL Item
M1 (M1)
CL Item
M2 (M2)
CL Item
M3 (M3)
CL Item
M4 (M4)
CL Item
M4eo (M4eo)
CL Item
M5 (M5)
CL Item
M5a (M5a)
CL Item
M5b (M5b)
CL Item
M6 (M6)
CL Item
M7 (M7)
CL Item
AML (not M3) (AML (not M3))
CL Item
unknown (unknown)
aPTT
Item
activated partial thromboplastin time (aPTT)
float
C0030605 (UMLS CUI [1])
Nights in Hospital
Item
Nights in hospital
float
C0420496 (UMLS CUI [1])
Basophils
Item
Basophils
integer
C0200641 (UMLS CUI [1])
CL Item
normal (0)
CL Item
+ (1)
CL Item
++ (2)
CL Item
+++ (3)
CL Item
++++ (4)
Promyelocytes
Item
Promyelocytes
float
C0455279 (UMLS CUI [1])
Metamyelocytes
Item
Metamyelocytes
float
C0229635 (UMLS CUI [1])
AP
Item
float
C0201850 (UMLS CUI [1])
ASAT/GOT
Item
float
C0201899 (UMLS CUI [1])
Uric acid
Item
Uric acid
float
C0041980 (UMLS CUI [1])
Neutrophils (Segmented&Bands)
Item
integer
C0200633 (UMLS CUI [1])
Sodium
Item
Sodium
float
C0337443 (UMLS CUI [1])
Myelocytes
Item
Myelocytes
float
C0455284 (UMLS CUI [1])
Potassium
Item
Potassium
float
C0202194 (UMLS CUI [1])
Molecular genetics
Item
Molecular genetics
text
C0086345 (UMLS CUI [1])
mds
Item
patients who previously had myelodysplastic syndrome.
boolean
C3463824 (UMLS CUI [1])
HLA-Typing indicator
Item
HLA-Typing performed?
boolean
C0242318 (UMLS CUI [1])
Serum Glucose
Item
Glucose (Serum)
float
C0202042 (UMLS CUI [1])
Exposure to Toxic Agents
Item
boolean
C0014412 (UMLS CUI [1])
Calcium
Item
Calcium
float
C0201925 (UMLS CUI [1])
Hepatitis B positivity
Item
boolean
C0019163 (UMLS CUI [1])
Hepatitis B positivity
Item
boolean
C0019163 (UMLS CUI [1])
Rhesus factor
Item
text
C0035403 (UMLS CUI [1])
Blood count
Item
Blood count
text
C0005771 (UMLS CUI [1])
CL Item
Family history (Family history)
CL Item
Previous diseases (Previous diseases)
CL Item
Baseline symptoms (Baseline symptoms)
Echocardiography
Item
Echocardiography report/performed
text
C0013516 (UMLS CUI [1])
Chemotherapy dose applied
Item
float
C2986497 (UMLS CUI [1])
Hematological remission indicator
Item
boolean
C0018943 (UMLS CUI [1])
Urea
Item
Urea
float
C0523961 (UMLS CUI [1])
ANC
Item
ANC/Absolute neutrophil count
float
C0948762 (UMLS CUI [1])
Hepatitis C positivity
Item
boolean
C0019196 (UMLS CUI [1])
Erythrocytes
Item
Erythrocytes
float
C0014792 (UMLS CUI [1])
CL Item
punctio sicca (0)
CL Item
hypo- (1)
CL Item
normo- (2)
CL Item
hypercellular (3)
CL Item
not evaluable (4)
Urinalysis
Item
Urinalysis
text
C0042014 (UMLS CUI [1])
Constitutional Chromosome Aberration/Complex Karyotype
Item
boolean
C3273253 (UMLS CUI [1])
HIV positivity
Item
HIV positivity
boolean
C0019682 (UMLS CUI [1])
Immunophenotyping
Item
Immunophenotyping performed
boolean
C0079611 (UMLS CUI [1])
Segmented neutrophils
Item
Segmented neutrophils (%)
integer
C0942466 (UMLS CUI [1])
CL Item
Recovered (1)
CL Item
Subsiding (2)
CL Item
Continuing (3)
CL Item
resolved with sequelae (4)
CL Item
increased symptoms (5)
CL Item
fatal (6)
Number of nucleated cells infused
Item
Number of nucleated cells infused
float
C1180059 (UMLS CUI [1])
Fever Days
Item
Number of Days with Fever higher than 38.5°C
integer
C0015967 (UMLS CUI [1])
Chromosome 8 trisomy
Item
boolean
C0432412 (UMLS CUI [1])
Hepatitis A positivity
Item
boolean
C0019159 (UMLS CUI [1])
Patient off study indicator
Item
boolean
C1518546 (UMLS CUI [1])
Body Temperature
Item
Body Temperature
float
C0005903 (UMLS CUI [1])
Coagulation
Item
Coagulation problems described?
boolean
C0005778 (UMLS CUI [1])
Magnesium
Item
Magnesium
float
C0364745 (UMLS CUI [1])
Differential Blood Count performed
Item
boolean
C0545131 (UMLS CUI [1])
Specimen ownership transfer
Item
Did the patient agree on storage of specimen for research purposes and agree on ownership transfer?
boolean
C3854286 (UMLS CUI [1])
C-reactive protein
Item
float
C0201657 (UMLS CUI [1])
Date of Death
Item
date
C1148348 (UMLS CUI [1])
GGT
Item
Gamma Glutamyl Transpeptidase Measurement
float
C0017040 (UMLS CUI [1])
Phosphate
Item
float
C1370010 (UMLS CUI [1])
Stab cells
Item
Stab cells/Neutrophil band form
integer
C1882076 (UMLS CUI [1])
FISH findings
Item
FISH findings, fluorescent in situ hybridization performed?
boolean
C0162789 (UMLS CUI [1])
Toxoplasmose positivity
Item
boolean
C0040558 (UMLS CUI [1])
Dyserythropoesis
Item
boolean
C0221143 (UMLS CUI [1])
ECG finding/report
Item
text
C1623258 (UMLS CUI [1])
Cellular Therapy, DLI
Item
Cellular Therapy, Donor Lymphocyte infusion
text
C1512034 (UMLS CUI [1])
CBFB Mutation Positivity
Item
boolean
C3276534 (UMLS CUI [1])
MCV
Item
float
C0524587 (UMLS CUI [1])
Dysgranulopoiesis
Item
Dysgranulopoiesis
boolean
C0312832 (UMLS CUI [1])
Fibrinogen
Item
Fibrinogen
float
C0016006 (UMLS CUI [1])
Dysmegakaryopoiesis
Item
boolean
C3700221 (UMLS CUI [1])
Smoking History
Item
text
C1519384 (UMLS CUI [1])
Albumin
Item
float
C0363885 (UMLS CUI [1])
Urinalysis Glucose
Item
float
C0004076 (UMLS CUI [1])
Erytrhoblasts
Item
integer
C0014762 (UMLS CUI [1])
Lipase
Item
float
C0023764 (UMLS CUI [1])
Number of analyzed Metaphases
Item
integer
C1621812 (UMLS CUI [1])
Ejection Fraction
Item
Ejection Fraction, EF
integer
C0232174 (UMLS CUI [1])
Hematocrit
Item
integer
C0518014 (UMLS CUI [1])
HSCT Donor ID
Item
text
C1718162 (UMLS CUI [1])
HSV positivity
Item
boolean
C0319232 (UMLS CUI [1])
MCH
Item
text
C0369183 (UMLS CUI [1])
CL Item
HLA-A (HLA-A)
CL Item
HLA-B (HLA-B)
CL Item
HLA-C (HLA-C)
CL Item
HLA-DR (HLA-DR)
CL Item
HLA-DQ (HLA-DQ)
Parvovirus positivity
Item
boolean
C0086776 (UMLS CUI [1])
CL Item
Evaluated: Absent (1)
CL Item
Evaluated: Present (2)
CL Item
Not evaluated (3)
CL Item
unknown (4)
t(9;11)(p22;q23) Translocation
Item
t(9;11)(p22;q23) Translocation positivity
boolean
C1515800 (UMLS CUI [1])
NPM1 Mutation Positivity
Item
boolean
C2826175 (UMLS CUI [1])
Ciclosporin-Level
Item
float
C0337448 (UMLS CUI [1])
Microbiology
Item
Microbiology diagnostics indicator
boolean
C0025952 (UMLS CUI [1])
Kell-System
Item
Kell Blood-Group System
text
C0022546 (UMLS CUI [1])
CEBPA Mutation Positivity
Item
boolean
C1413322 (UMLS CUI [1])
Creatinine Kinase
Item
float
C0010287 (UMLS CUI [1])
VZV positivity
Item
Varizella zoster virus positivity
boolean
C0042338 (UMLS CUI [1])
Serum Total Protein
Item
float
C0036836 (UMLS CUI [1])
Off Protocol Date
Item
Date when taken off protocol
date
C2985813 (UMLS CUI [1])
AML1 / ETO + RUNX1-RUNX1T1
Item
boolean
C1851466 (UMLS CUI [1])
Immunosuppression
Item
text
C0021079 (UMLS CUI [1])
PML-RARA Mutation Positivity
Item
boolean
C3887967 (UMLS CUI [1])
CL Item
White (White)
CL Item
Black (Black)
CL Item
Asian (Asian)
CL Item
American Indian/Alaska Native (American Indian/Alaska Native)
CL Item
Native Hawaiian/Other Pacific Islander (Native Hawaiian/Other Pacific Islander)
FLT3 Gene Positivity
Item
boolean
C1333568 (UMLS CUI [1])
BCR-ABL Mutation Positivity
Item
boolean
C1835417 (UMLS CUI [1])
Allergies/Hypersensitivity
Item
Is any allergy or hypersensitivity known?
text
C0020517 (UMLS CUI [1])
Prothrombin Time Test/PTT
Item
float
C0491338 (UMLS CUI [1])
FLT3 - Internal Tandem Duplicaton (ITD)
Item
boolean
C2348499 (UMLS CUI [1])
MCHC
Item
Mean corpuscular hemoglobin concentration
float
C0474535 (UMLS CUI [1])
t(3;3) Translocation
Item
boolean
C1515764 (UMLS CUI [1])
t(8;21) Translocation
Item
boolean
C1515794 (UMLS CUI [1])
t(6;9) Translocation
Item
boolean
C1515781 (UMLS CUI [1])
Red Blood Cell Transfusion Count
Item
How many red blood cell transfusions were administered?
integer
C0086252 (UMLS CUI [1])
Leukocyte Engraftment Date
Item
When did engraftment of leukocytes take place?
date
C0301944 (UMLS CUI [1,1])
C0023508 (UMLS CUI [1,2])
C0023508 (UMLS CUI [1,2])
Chest X-ray report
Item
text
C0039985 (UMLS CUI [1])
CL Item
methanol/acetic acid–fixed (1)
(Comment:en)
CL Item
frozen (2)
(Comment:en)
Storage of plasma sample
Item
Was a plasma sample stored?
boolean
C0444263 (UMLS CUI [1])
CL Item
Buccal Swab (Buccal Swab)
CL Item
skin biopsy (skin biopsy)
CL Item
sputum (sputum)
Neutropenia
Item
boolean
C0027947 (UMLS CUI [1])
Total cholesterol
Item
float
C0543421 (UMLS CUI [1])
Total triglycerides
Item
float
C0202236 (UMLS CUI [1])
Nonspecific esterase (NSE)
Item
float
C0054741 (UMLS CUI [1])
Lysozyme
Item
Lysozyme
text
C3541379 (UMLS CUI [1])
t(v;11)(v;q23)
Item
t(v;11)(v;q23) mutation
boolean
C1515714 (UMLS CUI [1])
BAALC overexpression
Item
BAALC overexpression
boolean
C1422571 (UMLS CUI [1])
inv(3)(q21q26.2)
Item
inv(3)(q21q26.2)
boolean
C1515666 (UMLS CUI [1])
RAS Mutation
Item
RAS Mutation
boolean
C0034678 (UMLS CUI [1])
inv(16)(p13.1q22)
Item
inv(16)(p13.1q22)
boolean
C1533174 (UMLS CUI [1])
EVI1 mutation
Item
boolean
C0082512 (UMLS CUI [1])
abnl(17p)
Item
abnl(17p) mutation
boolean
C0796349 (UMLS CUI [1])
WT1 mutation
Item
boolean
C0694898 (UMLS CUI [1])
del(7)
Item
del(7) mutation
boolean
C1517989 (UMLS CUI [1])
IDH1 Mutation
Item
IDH1 Mutation
boolean
C1415876 (UMLS CUI [1])
Cytoplamic Myeloperoxidase(cMPO)
Item
boolean
C2698399 (UMLS CUI [1])
CD14
Item
CD14
boolean
C0108768 (UMLS CUI [1])
CD15
Item
CD15+
boolean
C0080188 (UMLS CUI [1])
DEK-NUP214
Item
boolean
C1861917 (UMLS CUI [1])
CD64
Item
CD64
boolean
C0108796 (UMLS CUI [1])
MLLT3-MLL
Item
boolean
C1518129 (UMLS CUI [1])
CD42
Item
CD42
boolean
C1979868 (UMLS CUI [1])
CD38
Item
CD38+
boolean
C0075742 (UMLS CUI [1])
MN1 Mutation
Item
MN1 Mutation
boolean
C1417217 (UMLS CUI [1])
CD16
Item
CD16
boolean
C0108747 (UMLS CUI [1])
CD41
Item
CD41
boolean
C0032191 (UMLS CUI [1])
CD36
Item
CD36
boolean
C0054954 (UMLS CUI [1])
CD36
Item
CD36
boolean
C0054954 (UMLS CUI [1])
CD33
Item
CD33+
boolean
C0054952 (UMLS CUI [1])
CD11c
Item
CD11c
boolean
C0023395 (UMLS CUI [1])
CD4
Item
CD4
boolean
C0003323 (UMLS CUI [1])
CD133
Item
CD133
boolean
C1418946 (UMLS CUI [1])
CD235a
Item
CD235a
boolean
C0017955 (UMLS CUI [1])
CD61
Item
CD61
boolean
C0245726 (UMLS CUI [1])
CD117
Item
CD117
boolean
C1267996 (UMLS CUI [1])
CD11b
Item
CD11b
boolean
C1136310 (UMLS CUI [1])
del(5q)
Item
del(5q) Mutation
boolean
C152146 (UMLS CUI [1])
RUNX1 mutation
Item
boolean
C1335654 (UMLS CUI [1])
TET2 Mutation
Item
TET2 Mutation
boolean
C1825692 (UMLS CUI [1])
MLL rearranged
Item
MLL rearranged
boolean
C2826048 (UMLS CUI [1])
ERG Mutation
Item
ERG Mutation
boolean
C0599295 (UMLS CUI [1])
RPN1-EVI1 mutation
Item
boolean
C1449840 (UMLS CUI [1])
KIT Mutation
Item
KIT Mutation
boolean
C1416655 (UMLS CUI [1])
TP53
Item
boolean
C0079419 (UMLS CUI [1])
Minimal Residual Disease
Item
Minimal Residual Disease
boolean
C1511791 (UMLS CUI [1])
Urine Erythrocytes
Item
Urine Erythrocytes
float
C1254564 (UMLS CUI [1])
Urine leukocytes
Item
float
C1256582 (UMLS CUI [1])
Urine nitrit
Item
Urine nitrit positivity
boolean
C0580333 (UMLS CUI [1])
Urine pH
Item
float
C0042044 (UMLS CUI [1])