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ID

44429

Beschreibung

This ODM file contains Alcohol Breath Test, Cotinine Screen and Drug Screening. To be filled in at Screening and Sessions 1 and 2 (Day -1). Study ID: 109710 Clinical Study ID: DAN109710 Study Title: A single-blind, randomized, placebo controlled, two-period crossover fMRI study to investigate the effects of the D3 antagonist GSK598809 on neural and behavioural responses to food reward and reinforcement after a single oral dose of GSK598809 in overweight and obese subjects. Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT01039454 https://clinicaltrials.gov/ct2/show/NCT01039454 Sponsor: GlaxoSmithKline Collaborators: N/A Phase: Phase 1 Study Recruitment Status: Completed Generic Name: GSK598809 Trade Name: Study Indication: Substance Dependence Brief Summary: This novel compound is a new experimental treatment that may help people to stop compulsive overeating. Compulsive overeating or binge eating is one of the main reasons why people are overweight or obese. Recent research has shown that some kinds of overeating may be linked to a brain chemical called dopamine. There is some evidence that blocking the action of this chemical in animals can reduce food intake, particularly of foods that are high in fat and sugar. The purpose of this study is to find out if this compound (which blocks the effects of dopamine) has the same effect in overweight or obese people, as it does in animals.

Link

https://clinicaltrials.gov/ct2/show/NCT01039454

Stichworte

  1. 08.06.18 08.06.18 - Sarah Riepenhausen
  2. 20.09.21 20.09.21 -
Rechteinhaber

GlaxoSmithKline

Hochgeladen am

20. September 2021

DOI

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Lizenz

Creative Commons BY-NC 3.0

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    Effects of D3 antagonist GSK598809 on neural and behavioural responses to food reward/reinforcement after a single dose in overweight/obese subjects NCT01039454

    Alcohol Breath Test, Cotinine and Drugs Screenings (Screening and Sessions Visits)

    Administrative Data
    Beschreibung

    Administrative Data

    Alias
    UMLS CUI-1
    C1320722
    Type of Visit
    Beschreibung

    Visit

    Datentyp

    text

    Alias
    UMLS CUI [1]
    C0545082
    Subject Identifier
    Beschreibung

    Subject Identifier

    Datentyp

    text

    Alias
    UMLS CUI [1]
    C2348585
    Alcohol Breath Test
    Beschreibung

    Alcohol Breath Test

    Alias
    UMLS CUI-1
    C0202306
    Date Sample Taken
    Beschreibung

    Date Sample Taken

    Datentyp

    date

    Alias
    UMLS CUI [1,1]
    C1302413
    UMLS CUI [1,2]
    C0202306
    Result
    Beschreibung

    If positive, exclude subject from the study.

    Datentyp

    text

    Alias
    UMLS CUI [1,1]
    C0202304
    UMLS CUI [1,2]
    C1274040
    Cotinine Screen
    Beschreibung

    Cotinine Screen

    Alias
    UMLS CUI-1
    C0202363
    Date and Time sample Taken
    Beschreibung

    Date and Time sample Taken

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0202363
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C0200345
    Cotinine Finding
    Beschreibung

    If positive, exclude subject from the study.

    Datentyp

    text

    Alias
    UMLS CUI [1,1]
    C0202363
    UMLS CUI [1,2]
    C0243095
    Drug Screen
    Beschreibung

    Drug Screen

    Alias
    UMLS CUI-1
    C0373483
    Date and Time of Sample Taken
    Beschreibung

    Date and Time of Sample Taken

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0373483
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C0200345
    Drug
    Beschreibung

    Drug

    Datentyp

    text

    Alias
    UMLS CUI [1]
    C0086190
    UMLS CUI [2]
    C0013146
    Result
    Beschreibung

    If any of the drugs mentioned are positive, exclude subject from study

    Datentyp

    text

    Alias
    UMLS CUI [1,1]
    C1274040
    UMLS CUI [1,2]
    C0373483

    Ähnliche Modelle

    Alcohol Breath Test, Cotinine and Drugs Screenings (Screening and Sessions Visits)

    Name
    Typ
    Description | Question | Decode (Coded Value)
    Datentyp
    Alias
    Item Group
    Administrative Data
    C1320722 (UMLS CUI-1)
    Item
    Type of Visit
    text
    C0545082 (UMLS CUI [1])
    Code List
    Type of Visit
    CL Item
    Screening (Screening)
    CL Item
    Session 1 (Day -1) (Session 1 (Day -1))
    CL Item
    Session 2 (Session 2)
    Subject Identifier
    Item
    Subject Identifier
    text
    C2348585 (UMLS CUI [1])
    Item Group
    Alcohol Breath Test
    C0202306 (UMLS CUI-1)
    Date Sample Taken
    Item
    Date Sample Taken
    date
    C1302413 (UMLS CUI [1,1])
    C0202306 (UMLS CUI [1,2])
    Item
    Result
    text
    C0202304 (UMLS CUI [1,1])
    C1274040 (UMLS CUI [1,2])
    Code List
    Result
    CL Item
    positive (positive)
    CL Item
    negative (negative)
    Item Group
    Cotinine Screen
    C0202363 (UMLS CUI-1)
    Date and Time sample Taken
    Item
    Date and Time sample Taken
    datetime
    C0202363 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C0200345 (UMLS CUI [1,3])
    Item
    Cotinine Finding
    text
    C0202363 (UMLS CUI [1,1])
    C0243095 (UMLS CUI [1,2])
    Code List
    Cotinine Finding
    CL Item
    positive (positive)
    CL Item
    negative (negative)
    Item Group
    Drug Screen
    C0373483 (UMLS CUI-1)
    Date and Time of Sample Taken
    Item
    Date and Time of Sample Taken
    datetime
    C0373483 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C0200345 (UMLS CUI [1,3])
    Item
    Drug
    text
    C0086190 (UMLS CUI [1])
    C0013146 (UMLS CUI [2])
    Code List
    Drug
    CL Item
    Cocaine (Cocaine)
    CL Item
    Aphetamines (Aphetamines)
    CL Item
    Benzodiazepines (Benzodiazepines)
    CL Item
    Cannabinoids (Cannabinoids)
    CL Item
    Opiates (Opiates)
    CL Item
    Barbiturates (Barbiturates)
    CL Item
    Methadone (Methadone)
    Item
    Result
    text
    C1274040 (UMLS CUI [1,1])
    C0373483 (UMLS CUI [1,2])
    Code List
    Result
    CL Item
    positive (positive)
    CL Item
    negative (negative)

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