ID

44316

Beschreibung

AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors; ODM derived from: https://clinicaltrials.gov/show/NCT00819169

Link

https://clinicaltrials.gov/show/NCT00819169

Stichworte

Versionen (2)
  1. 28.12.17 28.12.17 -
  2. 20.09.21 20.09.21 -
Rechteinhaber

See clinicaltrials.gov

Hochgeladen am

20. September 2021

DOI

Für eine Beantragung loggen Sie sich ein.

Lizenz

Creative Commons BY 4.0
Modell Kommentare :

Hier können Sie das Modell kommentieren. Über die Sprechblasen an den Itemgruppen und Items können Sie diese spezifisch kommentieren.

Zurück zu Modell Kommentaren
Itemgroup Kommentare für :

Item Kommentare für :

Um Formulare herunterzuladen müssen Sie angemeldet sein. Bitte loggen Sie sich ein oder registrieren Sie sich kostenlos.

Eligibility Colorectal Cancer NCT00819169

Englisch

Eligibility Colorectal Cancer NCT00819169

1 Formulare  
Inclusion Criteria
Beschreibung

Inclusion Criteria

Alias
UMLS CUI
C1512693
part 1: histologically or cytologically confirmed, locally advanced or metastatic, treatment-refractory solid tumors
Beschreibung

Solid tumour Advanced Locally Unresponsive to Treatment | Solid tumour metastatic Unresponsive to Treatment

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0280100
UMLS CUI [1,2]
C0205179
UMLS CUI [1,3]
C1517927
UMLS CUI [1,4]
C0205269
UMLS CUI [2,1]
C0280100
UMLS CUI [2,2]
C1522484
UMLS CUI [2,3]
C0205269
part 2: histologically or cytologically confirmed, locally advanced or metastatic: nsclc (squamous or non-squamous cell carcinoma; up to 2 prior treatment regimens), colorectal cancer (up to 2 prior treatment regimens), pancreatic cancer (up to 1 prior treatment regimen), ovarian cancer (up to 2 prior treatment regimens), or sarcoma (up to 2 prior treatment regimens), according to cohort availability
Beschreibung

Non-Small Cell Lung Carcinoma Advanced Locally | Non-small cell lung cancer metastatic | Therapeutic procedure Quantity Squamous cell carcinoma | Therapeutic procedure Quantity Nonsquamous nonsmall cell neoplasm of lung | Therapeutic procedure Quantity Colorectal Carcinoma | Therapeutic procedure Quantity Pancreatic carcinoma | Therapeutic procedure Quantity Ovarian Carcinoma | Therapeutic procedure Quantity Sarcoma

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0007131
UMLS CUI [1,2]
C0205179
UMLS CUI [1,3]
C1517927
UMLS CUI [2]
C0278987
UMLS CUI [3,1]
C0087111
UMLS CUI [3,2]
C1265611
UMLS CUI [3,3]
C0007137
UMLS CUI [4,1]
C0087111
UMLS CUI [4,2]
C1265611
UMLS CUI [4,3]
C2585890
UMLS CUI [5,1]
C0087111
UMLS CUI [5,2]
C1265611
UMLS CUI [5,3]
C0009402
UMLS CUI [6,1]
C0087111
UMLS CUI [6,2]
C1265611
UMLS CUI [6,3]
C0235974
UMLS CUI [7,1]
C0087111
UMLS CUI [7,2]
C1265611
UMLS CUI [7,3]
C0029925
UMLS CUI [8,1]
C0087111
UMLS CUI [8,2]
C1265611
UMLS CUI [8,3]
C1261473
eastern cooperative group (ecog performance status of 0 or 1
Beschreibung

ECOG performance status

Datentyp

boolean

Alias
UMLS CUI [1]
C1520224
women or men ≥16 years of age
Beschreibung

Age

Datentyp

boolean

Alias
UMLS CUI [1]
C0001779
adequate hematology, renal, hepatic, coagulation and glycemic function.
Beschreibung

Hematologic function | Renal function | Liver function | Blood coagulation | Glycemia function

Datentyp

boolean

Alias
UMLS CUI [1]
C0221130
UMLS CUI [2]
C0232804
UMLS CUI [3]
C0232741
UMLS CUI [4]
C0005778
UMLS CUI [5,1]
C0005802
UMLS CUI [5,2]
C0031843
Exclusion Criteria
Beschreibung

Exclusion Criteria

Alias
UMLS CUI
C0680251
presence of uncontrolled central nervous system (cns) disease
Beschreibung

CNS disorder Uncontrolled

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0007682
UMLS CUI [1,2]
C0205318
systemic chemotherapy, hormonal therapy, immunotherapy, experimental or approved anticancer proteins/antibodies therapy ≤28 days before enrollment.
Beschreibung

Systemic Chemotherapy | Hormone Therapy | Immunotherapy | Monoclonal antibodies, antineoplastic

Datentyp

boolean

Alias
UMLS CUI [1]
C1883256
UMLS CUI [2]
C0279025
UMLS CUI [3]
C0021083
UMLS CUI [4]
C3542957
prior treatment with death receptor agonists (including but not limited to rhapo2l/trail [amg951], apomab, mapatumumab, lexatumumab, cs-1008)
Beschreibung

Death Receptor agonists | AMG 951 | apomab | mapatumumab | lexatumumab | CS-1008

Datentyp

boolean

Alias
UMLS CUI [1,1]
C1720947
UMLS CUI [1,2]
C0243192
UMLS CUI [2,1]
C2830007
UMLS CUI [2,2]
C2346838
UMLS CUI [3]
C1665688
UMLS CUI [4]
C1721684
UMLS CUI [5]
C1831890
prior treatment with igf receptor antagonists (including but not limited to cp-751, 871, mk0646, ave1642 or imc-a12)
Beschreibung

IGF Receptor antagonists | CP 751 | Other Coding | MK 0646 | AVE1642 | IMC-A12

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0140079
UMLS CUI [1,2]
C0243076
UMLS CUI [2]
C1707143
UMLS CUI [3]
C3846158
UMLS CUI [4]
C1831888
UMLS CUI [5]
C2703165
UMLS CUI [6]
C3180625
Zum Seitenanfang zurückkehren

Ähnliche Modelle

Eligibility Colorectal Cancer NCT00819169

1 Formulare
Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
C1512693 (UMLS CUI)
Solid tumour Advanced Locally Unresponsive to Treatment | Solid tumour metastatic Unresponsive to Treatment
Item
part 1: histologically or cytologically confirmed, locally advanced or metastatic, treatment-refractory solid tumors
boolean
C0280100 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C1517927 (UMLS CUI [1,3])
C0205269 (UMLS CUI [1,4])
C0280100 (UMLS CUI [2,1])
C1522484 (UMLS CUI [2,2])
C0205269 (UMLS CUI [2,3])
Non-Small Cell Lung Carcinoma Advanced Locally | Non-small cell lung cancer metastatic | Therapeutic procedure Quantity Squamous cell carcinoma | Therapeutic procedure Quantity Nonsquamous nonsmall cell neoplasm of lung | Therapeutic procedure Quantity Colorectal Carcinoma | Therapeutic procedure Quantity Pancreatic carcinoma | Therapeutic procedure Quantity Ovarian Carcinoma | Therapeutic procedure Quantity Sarcoma
Item
part 2: histologically or cytologically confirmed, locally advanced or metastatic: nsclc (squamous or non-squamous cell carcinoma; up to 2 prior treatment regimens), colorectal cancer (up to 2 prior treatment regimens), pancreatic cancer (up to 1 prior treatment regimen), ovarian cancer (up to 2 prior treatment regimens), or sarcoma (up to 2 prior treatment regimens), according to cohort availability
boolean
C0007131 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C1517927 (UMLS CUI [1,3])
C0278987 (UMLS CUI [2])
C0087111 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0007137 (UMLS CUI [3,3])
C0087111 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
C2585890 (UMLS CUI [4,3])
C0087111 (UMLS CUI [5,1])
C1265611 (UMLS CUI [5,2])
C0009402 (UMLS CUI [5,3])
C0087111 (UMLS CUI [6,1])
C1265611 (UMLS CUI [6,2])
C0235974 (UMLS CUI [6,3])
C0087111 (UMLS CUI [7,1])
C1265611 (UMLS CUI [7,2])
C0029925 (UMLS CUI [7,3])
C0087111 (UMLS CUI [8,1])
C1265611 (UMLS CUI [8,2])
C1261473 (UMLS CUI [8,3])
ECOG performance status
Item
eastern cooperative group (ecog performance status of 0 or 1
boolean
C1520224 (UMLS CUI [1])
Age
Item
women or men ≥16 years of age
boolean
C0001779 (UMLS CUI [1])
Hematologic function | Renal function | Liver function | Blood coagulation | Glycemia function
Item
adequate hematology, renal, hepatic, coagulation and glycemic function.
boolean
C0221130 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C0232741 (UMLS CUI [3])
C0005778 (UMLS CUI [4])
C0005802 (UMLS CUI [5,1])
C0031843 (UMLS CUI [5,2])
Item Group
C0680251 (UMLS CUI)
CNS disorder Uncontrolled
Item
presence of uncontrolled central nervous system (cns) disease
boolean
C0007682 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Systemic Chemotherapy | Hormone Therapy | Immunotherapy | Monoclonal antibodies, antineoplastic
Item
systemic chemotherapy, hormonal therapy, immunotherapy, experimental or approved anticancer proteins/antibodies therapy ≤28 days before enrollment.
boolean
C1883256 (UMLS CUI [1])
C0279025 (UMLS CUI [2])
C0021083 (UMLS CUI [3])
C3542957 (UMLS CUI [4])
Death Receptor agonists | AMG 951 | apomab | mapatumumab | lexatumumab | CS-1008
Item
prior treatment with death receptor agonists (including but not limited to rhapo2l/trail [amg951], apomab, mapatumumab, lexatumumab, cs-1008)
boolean
C1720947 (UMLS CUI [1,1])
C0243192 (UMLS CUI [1,2])
C2830007 (UMLS CUI [2,1])
C2346838 (UMLS CUI [2,2])
C1665688 (UMLS CUI [3])
C1721684 (UMLS CUI [4])
C1831890 (UMLS CUI [5])
IGF Receptor antagonists | CP 751 | Other Coding | MK 0646 | AVE1642 | IMC-A12
Item
prior treatment with igf receptor antagonists (including but not limited to cp-751, 871, mk0646, ave1642 or imc-a12)
boolean
C0140079 (UMLS CUI [1,1])
C0243076 (UMLS CUI [1,2])
C1707143 (UMLS CUI [2])
C3846158 (UMLS CUI [3])
C1831888 (UMLS CUI [4])
C2703165 (UMLS CUI [5])
C3180625 (UMLS CUI [6])
Zum Seitenanfang zurückkehren 

Kontakt

Benutzen Sie dieses Formular für Rückmeldungen, Fragen und Verbesserungsvorschläge.

Mit * gekennzeichnete Felder sind notwendig.

Hilfe

Benötigen Sie Hilfe bei der Suche? Um mehr Details zu erfahren und die Suche effektiver nutzen zu können schauen Sie sich doch das entsprechende Video auf unserer Tutorial Seite an.

Zum Video