intrahepatic artery infusional therapy using fudr
Item
patients must not have been previously treated with intrahepatic artery infusional therapy using fudr.
boolean
C0016343 (UMLS CUI [1])
chemotherapy, radiotherapy or biologic therapy
Item
patients mush have had no chemotherapy, radiotherapy or biologic therapy for their malignancy in the month prior to the liver perfusion and must have recovered from all side effects.
boolean
C0392920 (UMLS CUI [1])
C1522449 (UMLS CUI [2])
C0005527 (UMLS CUI [3])
ecog
Item
patients must have an ecog performance standard of 0, 1 or 2 on the day prior to treatment.
boolean
C1520224 (UMLS CUI [1])
adequate hepatic function, bilirubin, pt and ptt
Item
patients must have adequate hepatic function as evidence by bilirubin less than 2.0 and a pt and ptt that are within 1-2 seconds of the upper normal limit.
boolean
C0232741 (UMLS CUI [1,1])
C0205411 (UMLS CUI [1,2])
C1278039 (UMLS CUI [2])
C0033707 (UMLS CUI [3])
C0030605 (UMLS CUI [4])
cirrhosis, portal hypertension
Item
patients must not have biopsy proven cirrhosis or evidence of significant portal hypertension by history, endoscopy, or radiologic studies.
boolean
C0023890 (UMLS CUI [1])
C0020541 (UMLS CUI [2])
congestive heart failure, lvef
Item
patients must not have a history of congestive heart failure with an lvef less than 40%.
boolean
C0018802 (UMLS CUI [1])
C0428772 (UMLS CUI [2])
copd, chronic pulmonary disease, pft`s
Item
patients must not have copd or other chronic pulmonary disease with pft's less than 50% predicted for age.
boolean
C0024115 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C0024117 (UMLS CUI [2])
C0024119 (UMLS CUI [3])
Age
Item
patients must be 18 years of age or older.
boolean
C0001779 (UMLS CUI [1])
platelet count, hct, white blood count, creatinine, creatinine clearance
Item
patients must have a platelet count greater than 100,000 a hct greater than 27.0, a white blood count greater than 3000/micro liters, and a creatinine less than or equal to 1.5 or a creatinine clearance of greater than 60 ml/min.
boolean
C0005821 (UMLS CUI [1])
C0518014 (UMLS CUI [2])
C0023508 (UMLS CUI [3])
C0201976 (UMLS CUI [4])
C0373595 (UMLS CUI [5])
pregnant or nursing.
Item
patients must not be pregnant or nursing.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
immunosuppressive drugs, anticoagulation
Item
patients must not be taking immunosuppressive drugs or on chronic anticoagulation.
boolean
C0021081 (UMLS CUI [1])
C0003281 (UMLS CUI [2])
active infection
Item
patients must not have an active infection.
boolean
C0009488 (UMLS CUI [1])
iodine contrast agents, premedication with antihistamines and steroids
Item
patients must not have severe allergic reactions to iodine contrast which can not be controlled by premedication with antihistamines and steroids.
boolean
C0020517 (UMLS CUI [1,1])
C0443076 (UMLS CUI [1,2])
C0019590 (UMLS CUI [2])
C0038317 (UMLS CUI [3])
hiv
Item
patients must not have hiv disease.
boolean
C0019682 (UMLS CUI [1])
written informed consent
Item
patients must be aware of the neoplastic nature of his/her illness, the experimental nature of the therapy, alternative treatments, potential benefits, and risks. the patient must be willing to sign an informed consent.
boolean
C0021430 (UMLS CUI [1])