Informações:
Falhas:
ID
42247
Descrição
Ticagrelor is a new, reversible binding, anti-platelet medication. Anti-platelet medications work to prevent the formation of blood clots. Ticagrelor is being developed as a treatment for patients with acute coronary syndrome (ACS). ACS is a term that is used to describe both heart attacks in progress or the imminent threat of a heart attack. ACS is usually caused by the formation of a blood clot in an artery that partially or totally blocks the blood supply to a portion of the heart muscle. Ticagrelor will be compared with clopidogrel to determine which drug, when either is used in conjunction with aspirin, is better at reducing deaths from vascular causes, future heart attacks and/or strokes in patients with ACS. https://clinicaltrials.gov/ct2/show/NCT00391872
Link
https://clinicaltrials.gov/ct2/show/NCT00391872
Palavras-chave
Versões (3)
- 28/11/2015 28/11/2015 -
- 14/04/2021 14/04/2021 - Ahmed Rafee, MD
- 15/04/2021 15/04/2021 - Ahmed Rafee, MD
Titular dos direitos
AstraZeneca
Transferido a
15 de abril de 2021
DOI
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Licença
Creative Commons BY 4.0
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Excerpt PLATO Acute coronary Syndrome NCT00391872
End of Treatment Visit
Similar models
End of Treatment Visit
Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de dados
Alias
Visit date
Item
Visit date
date
C1320303 (UMLS CUI [1])
Adverse event
Item
Adverse event
boolean
C0877248 (UMLS CUI [1])
Stroke/TIA
Item
Stroke/TIA
boolean
C0038454|C0007787 (UMLS CUI [1])
Arterial thrombosis
Item
Other arterial thrombotic event
boolean
C0151942 (UMLS CUI [1])
Hemorrhage
Item
Bleeding
boolean
C0019080 (UMLS CUI [1])
Myocardial infarction
Item
Myocardial infarction
boolean
C0027051 (UMLS CUI [1])
Myocardial ischaemia
Item
Recurrent cardiac ischaemia/severe recurrent cardiac ischaemia
boolean
C0151744 (UMLS CUI [1])
CL Item
I. Ordinary physical activity does not cause angina (I. Ordinary physical activity does not cause angina)
I (UMLS CUI-1)
CL Item
II. Slight limitation of ordinary activity (II. Slight limitation of ordinary activity)
I (UMLS CUI-1)
CL Item
III. Marked limitation of ordinary activity (III. Marked limitation of ordinary activity)
I (UMLS CUI-1)
CL Item
IV. Inability to carry out any physical activity without discomfort - angina syndrome may be present at rest (IV. Inability to carry out any physical activity without discomfort - angina syndrome may be present at rest)
I (UMLS CUI-1)
Operation
Item
Has any procedure or operation been performed during the index event hospitalization
boolean
C0543467 (UMLS CUI [1])
Coronary angiography
Item
Coronary angiography
boolean
C0085532 (UMLS CUI [1])
Percutaneous coronary revascularization
Item
Percutaneous coronary revascularization
boolean
C0877341 (UMLS CUI [1])
Cardiac surgery
Item
Cardiac surgery
boolean
C0018821 (UMLS CUI [1])
Revascularization
Item
Non-coronary revascularization
boolean
C0581603 (UMLS CUI [1])
Other cardiovascular procedure
Item
Other cardiovascular procedure
boolean
C0189573 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,2])
CT or MRI imaging
Item
CT or MRI imaging
boolean
C0024485|C0040405 (UMLS CUI [1])
Invasive procedure
Item
Non-cardiovascular invasive procedure
boolean
C1548804 (UMLS CUI [1])
Stress test
Item
Stress test
boolean
C1384495 (UMLS CUI [1])
Echocardiography
Item
Echocardiography/radionuclide angiography
boolean
C0013516 (UMLS CUI [1])
Cardiac Pacemaker
Item
Pacemaker
boolean
C0030163 (UMLS CUI [1])
Intracardial defibrillator
Item
Intracardial defibrillator
boolean
C1273352 (UMLS CUI [1])
IABP
Item
Intra-aortic balloon pump
boolean
C0021860 (UMLS CUI [1])
Left ventricular assist device
Item
Left ventricular assist device
boolean
C0181598 (UMLS CUI [1])
Electrophysiology study
Item
Electrophysiology study
boolean
C1446476 (UMLS CUI [1])
Holter monitoring
Item
Unplanned Holter monitoring
boolean
C0013801 (UMLS CUI [1])
Swan Ganz catheter
Item
Swan Ganz catheter
boolean
C0007438 (UMLS CUI [1])
Ventilator
Item
Ventilator
boolean
C0087153 (UMLS CUI [1])
Ventilation/perfusion scan
Item
Ventilation/perfusion scan
boolean
C0560738 (UMLS CUI [1])
Pulmonary angiography
Item
Pulmonary angiography
boolean
C0677490 (UMLS CUI [1])
Other
Item
Other
text
C0205394 (UMLS CUI [1])
Transfusion
Item
Has any transfusion been performed during the index event hospitalization
boolean
C1879316 (UMLS CUI [1])
Hospitalization
Item
Has Subject been hospitalized since previous visit
boolean
C0019993 (UMLS CUI [1])
CL Item
Normal (1)
I (UMLS CUI-1)
CL Item
Abnormal (2)
I (UMLS CUI-1)
CL Item
Not done (3)
I (UMLS CUI-1)
Blood pressure
Item
Blood pressure, supine
integer
C0005823 (UMLS CUI [1])
Weight
Item
Weight
float
C0005910 (UMLS CUI [1])
Assessment applicable for Subject
Item
Assessment applicable for Subject
boolean
C0681850 (UMLS CUI [1,1])
C0220825 (UMLS CUI [1,2])
C0220825 (UMLS CUI [1,2])
Pregnancy test date
Item
Sampling date
date
C0032976 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0011008 (UMLS CUI [1,2])
Pregnant
Item
Pregnancy test, urine
boolean
C0549206 (UMLS CUI [1])
Date of ECG
Item
Date of ECG
date
C2826640 (UMLS CUI [1])
Heart rate
Item
Heart rate
integer
C0018810 (UMLS CUI [1])
Q waves
Item
New or presumed new Q waves since admission
boolean
C1305738 (UMLS CUI [1])
Q wave symptoms
Item
Any symptoms since previous visit that could explain the new or presumed new Q waves
boolean
C0429090 (UMLS CUI [1,1])
C2347946 (UMLS CUI [1,2])
C1457887 (UMLS CUI [1,3])
C2347946 (UMLS CUI [1,2])
C1457887 (UMLS CUI [1,3])
Item
Functional status according to New York Heart Association (NYHA) - modified
text
C1275491 (UMLS CUI [1])
CL Item
No limitation of physical activity: ordinary physical exercise does not cause undue fatigue, palpitations or dyspnoea (I)
CL Item
Slight limitation of physical activity: comfortable at rest but ordinary activity results in fatigue, palpitations or dyspnoea (II)
CL Item
Marked limitation of physical activity: comfortable at rest but less than ordinary activity results in symptoms (III)
CL Item
Unable to carry out any physical activity without discomfort: symptoms of congestive heart failure (CHF) are present even at rest with increased discomfort with any physical activity (IV)
Item Group
EQ-5D Health-Related Quality of Life Questionnaire
CL Item
I have no problems in walking about (1)
I (UMLS CUI-1)
CL Item
I have some problems in walking about (2)
I (UMLS CUI-1)
CL Item
I am confined to bed3 (3)
I (UMLS CUI-1)
CL Item
Missing/multiple responses (4)
I (UMLS CUI-1)
CL Item
I have no problems with self-care (1)
I (UMLS CUI-1)
CL Item
I have some problems washing or dressing myself (2)
I (UMLS CUI-1)
CL Item
I am unable to wash or dress myself (3)
I (UMLS CUI-1)
CL Item
Missing/multiple responses (4)
I (UMLS CUI-1)
CL Item
I have no problems with performing my usual activities (1)
I (UMLS CUI-1)
CL Item
I have some problems with performing my usual activities (2)
I (UMLS CUI-1)
CL Item
I am unable to perform my usual activities (3)
I (UMLS CUI-1)
CL Item
Missing/multiple responses (4)
I (UMLS CUI-1)
CL Item
I have no pain or discomfort (1)
I (UMLS CUI-1)
CL Item
I have moderate pain or discomfort (2)
I (UMLS CUI-1)
CL Item
I have extreme pain or discomfort (3)
I (UMLS CUI-1)
CL Item
Missing/multiple responses (4)
I (UMLS CUI-1)
CL Item
I am not anxious or depressed (1)
I (UMLS CUI-1)
CL Item
I am moderately anxious or depressed (2)
I (UMLS CUI-1)
CL Item
I am extremely anxious or depressed (3)
I (UMLS CUI-1)
CL Item
Missing/multiple responses (4)
I (UMLS CUI-1)
Aspirin
Item
Subject will continue on ASA
boolean
C0004057 (UMLS CUI [1])
Aspirin dose
Item
integer
C0004057 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0178602 (UMLS CUI [1,2])
Clopidogrel
Item
Subject will continue on open clopidogrel (75 mg od)
boolean
C0070166 (UMLS CUI [1])
Clopidogrel loading dose
Item
If Yes, will Subject receive a transition loading dose
boolean
C0070166 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0178602 (UMLS CUI [1,2])
Item
Subject will continue on other antiplatelet agent
text
C1096021 (UMLS CUI [1])
CL Item
Ticlopidine (1)
C0040207 (UMLS CUI-1)
CL Item
Dipyridamole (2)
C0012582 (UMLS CUI-1)
CL Item
Other (3)
I (UMLS CUI-1)