ID
42247
Description
Ticagrelor is a new, reversible binding, anti-platelet medication. Anti-platelet medications work to prevent the formation of blood clots. Ticagrelor is being developed as a treatment for patients with acute coronary syndrome (ACS). ACS is a term that is used to describe both heart attacks in progress or the imminent threat of a heart attack. ACS is usually caused by the formation of a blood clot in an artery that partially or totally blocks the blood supply to a portion of the heart muscle. Ticagrelor will be compared with clopidogrel to determine which drug, when either is used in conjunction with aspirin, is better at reducing deaths from vascular causes, future heart attacks and/or strokes in patients with ACS. https://clinicaltrials.gov/ct2/show/NCT00391872
Link
https://clinicaltrials.gov/ct2/show/NCT00391872
Keywords
Versions (3)
- 11/28/15 11/28/15 -
- 4/14/21 4/14/21 - Ahmed Rafee, MD
- 4/15/21 4/15/21 - Ahmed Rafee, MD
Copyright Holder
AstraZeneca
Uploaded on
April 15, 2021
DOI
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License
Creative Commons BY 4.0
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Excerpt PLATO Acute coronary Syndrome NCT00391872
Section Procedures and Operations
Description
Cardiac Surgery
Alias
- UMLS CUI-1
- C0018821
Description
Date of procedure
Data type
datetime
Alias
- UMLS CUI [1]
- C2584899
Description
Procedure number
Data type
text
Alias
- UMLS CUI [1,1]
- C0087111
- UMLS CUI [1,2]
- C0237753
Description
Urgent procedure
Data type
boolean
Alias
- UMLS CUI [1]
- C3272275
Description
Most recent AZD6140/placebo dose prior to surgery
Data type
datetime
Alias
- UMLS CUI [1,1]
- C3173975
- UMLS CUI [1,2]
- C1608718
Description
Most recent clopidogrel/placebo dose prior to surgery
Data type
datetime
Alias
- UMLS CUI [1,1]
- C0070166
- UMLS CUI [1,2]
- C3173975
Description
Procedure type
Data type
text
Alias
- UMLS CUI [1]
- C0455713
Description
Number of grafts placed
Data type
integer
Alias
- UMLS CUI [1]
- C1391985
Description
Were any grafts placed to the target vessel of the index event
Data type
boolean
Alias
- UMLS CUI [1]
- C3543860
Description
Were any grafts placed to a previously treated vessel
Data type
boolean
Alias
- UMLS CUI [1,1]
- C0740038
- UMLS CUI [1,2]
- C0205156
Description
Were any grafts placed due to stent thrombosis
Data type
boolean
Alias
- UMLS CUI [1,1]
- C0740038
- UMLS CUI [1,2]
- C0678226
- UMLS CUI [1,3]
- C0040053
Description
Chest tube drainage volume within first 24 hours
Data type
integer
Measurement units
- ml
Alias
- UMLS CUI [1]
- C0008034
Description
Cardiopulmonary bypass
Data type
boolean
Alias
- UMLS CUI [1]
- C0007202
Description
Haemostatic agent
Data type
text
Alias
- UMLS CUI [1]
- C0019120
Description
Local cardiac biomarker measurements
Data type
text
Alias
- UMLS CUI [1]
- C1271630
Description
Central lab blood samples for analysis of CK-MB and Troponin I have been collected
Data type
boolean
Alias
- UMLS CUI [1,1]
- C0010290
- UMLS CUI [1,2]
- C0041199
Description
Accession number (Pre-CABG)
Data type
text
Alias
- UMLS CUI [1,1]
- C1510755
- UMLS CUI [1,2]
- C0332152
- UMLS CUI [1,3]
- C0010055
Description
Accession number (8-12 hrs post CABG)
Data type
text
Alias
- UMLS CUI [1,1]
- C1510755
- UMLS CUI [1,2]
- C0332152
- UMLS CUI [1,3]
- C0010055
Description
Accession number (12-24 hrs post CABG)
Data type
text
Alias
- UMLS CUI [1,1]
- C1510755
- UMLS CUI [1,2]
- C0332152
- UMLS CUI [1,3]
- C0010055
Description
Additional cardiac surgeries
Data type
boolean
Alias
- UMLS CUI [1]
- C0018821
Description
Coronary Angiography
Alias
- UMLS CUI-1
- C0085532
Description
Procedure date and time
Data type
datetime
Alias
- UMLS CUI [1]
- C2584899
Description
Urgent procedure
Data type
boolean
Alias
- UMLS CUI [1]
- C3272275
Description
Coronary stenosis
Data type
text
Alias
- UMLS CUI [1]
- C0242231
Description
Cardiac ejection fraction
Data type
text
Alias
- UMLS CUI [1]
- C0232174
Description
Additional coronary angiographies
Data type
boolean
Alias
- UMLS CUI [1]
- C0085532
Description
CT or MRI Imaging
Description
Procedure date
Data type
datetime
Alias
- UMLS CUI [1]
- C2584899
Description
Procedure type
Data type
text
Alias
- UMLS CUI [1]
- C0455713
Description
CT location
Data type
text
Alias
- UMLS CUI [1,1]
- C0040405
- UMLS CUI [1,2]
- C0450429
Description
MRI Location
Data type
text
Alias
- UMLS CUI [1,1]
- C0024485
- UMLS CUI [1,2]
- C0450429
Description
Additional CT or MRI imaging performed since last visit
Data type
boolean
Alias
- UMLS CUI [1]
- C0024485|C0040405
Description
Non-coronary Revascularization
Description
Non-cardiovascular Invasive Procedure
Description
Stress Test
Alias
- UMLS CUI-1
- C1384495
Description
Procedure date
Data type
datetime
Alias
- UMLS CUI [1]
- C2584899
Description
Cardiac stress test
Data type
text
Alias
- UMLS CUI [1]
- C1384495
Description
Result of stress test
Data type
text
Alias
- UMLS CUI [1,1]
- C1274040
- UMLS CUI [1,2]
- C1384495
Description
Additional stress tests
Data type
boolean
Alias
- UMLS CUI [1]
- C1384495
Description
Echocardiography/Radionuclide Angiography
Alias
- UMLS CUI-1
- C0013516
Description
Procedure date
Data type
datetime
Alias
- UMLS CUI [1]
- C2584899
Description
Cardiac ejection fraction
Data type
text
Alias
- UMLS CUI [1]
- C0232174
Description
Additional echocardiographies/radionuclide angiographies
Data type
boolean
Alias
- UMLS CUI [1]
- C0013516
Description
Percutaneous Coronary Revascularization
Alias
- UMLS CUI-1
- C1532338
Description
Procedure date
Data type
datetime
Alias
- UMLS CUI [1]
- C2584899
Description
Urgent procedure
Data type
boolean
Alias
- UMLS CUI [1]
- C3272275
Description
Procedure type
Data type
text
Alias
- UMLS CUI [1]
- C0455713
Description
If PCI without stent, fill in below
Data type
text
Alias
- UMLS CUI [1]
- C0455713
Description
Number of vessels treated
Data type
integer
Alias
- UMLS CUI [1,1]
- C0005847
- UMLS CUI [1,2]
- C0750480
Description
Was PCI performed to the target vessel of the index event
Data type
boolean
Alias
- UMLS CUI [1,1]
- C1532338
- UMLS CUI [1,2]
- C0205156
Description
Was PCI performed to a previously treated vessel
Data type
boolean
Alias
- UMLS CUI [1,1]
- C1532338
- UMLS CUI [1,2]
- C0205156
Description
Coronary stent thrombosis
Data type
boolean
Alias
- UMLS CUI [1]
- C1536080
Description
Number of drug eluting stents placed
Data type
integer
Alias
- UMLS CUI [1,1]
- C2024081
- UMLS CUI [1,2]
- C1262327
Description
Number of bare metal stents placed
Data type
integer
Alias
- UMLS CUI [1,1]
- C2024081
- UMLS CUI [1,2]
- C2825200
Description
Were any stents placed to the target vessel of the index event
Data type
boolean
Alias
- UMLS CUI [1,1]
- C0687568
- UMLS CUI [1,2]
- C0205156
- UMLS CUI [1,3]
- C0150312
Description
Were any stents placed to a previously treated vessel
Data type
float
Alias
- UMLS CUI [1,1]
- C0687568
- UMLS CUI [1,2]
- C0205156
- UMLS CUI [1,3]
- C0150312
Description
Were any stents placed for a stent thrombosis
Data type
boolean
Alias
- UMLS CUI [1,1]
- C3272316
- UMLS CUI [1,2]
- C0678226
- UMLS CUI [1,3]
- C0040053
Description
Main reason for revascularization
Data type
text
Alias
- UMLS CUI [1,1]
- C0027056
- UMLS CUI [1,2]
- C0392360
Description
Cardiac biomarker measurements
Data type
text
Alias
- UMLS CUI [1]
- C1271630
Description
CK-MB and Troponin I
Data type
boolean
Alias
- UMLS CUI [1]
- C0523584|C0920210
Description
Accession number (Pre-PCI)
Data type
text
Alias
- UMLS CUI [1,1]
- C1510755
- UMLS CUI [1,2]
- C0332152
- UMLS CUI [1,3]
- C1532338
Description
Accession number (8-12 hrs post pCI)
Data type
text
Alias
- UMLS CUI [1,1]
- C1510755
- UMLS CUI [1,2]
- C0332152
- UMLS CUI [1,3]
- C1532338
Description
Accession number (12-24 hrs post PCI)
Data type
text
Alias
- UMLS CUI [1,1]
- C1510755
- UMLS CUI [1,2]
- C0332152
- UMLS CUI [1,3]
- C1532338
Description
Additional percutaneous coronary revascularizations
Data type
boolean
Alias
- UMLS CUI [1]
- C1532338
Description
Transfusion of Blood Products
Alias
- UMLS CUI-1
- C0005841
Similar models
Section Procedures and Operations
C0021708 (UMLS CUI [1,2])
C0237753 (UMLS CUI [1,2])
C1608718 (UMLS CUI [1,2])
C3173975 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,2])
C0678226 (UMLS CUI [1,2])
C0040053 (UMLS CUI [1,3])
C0041199 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,2])
C0010055 (UMLS CUI [1,3])
C0332152 (UMLS CUI [1,2])
C0010055 (UMLS CUI [1,3])
C0332152 (UMLS CUI [1,2])
C0010055 (UMLS CUI [1,3])
C1384495 (UMLS CUI [1,2])
C0750480 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,2])
C1262327 (UMLS CUI [1,2])
C2825200 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,2])
C0150312 (UMLS CUI [1,3])
C0205156 (UMLS CUI [1,2])
C0150312 (UMLS CUI [1,3])
C0678226 (UMLS CUI [1,2])
C0040053 (UMLS CUI [1,3])
C0392360 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,2])
C1532338 (UMLS CUI [1,3])
C0332152 (UMLS CUI [1,2])
C1532338 (UMLS CUI [1,3])
C0332152 (UMLS CUI [1,2])
C1532338 (UMLS CUI [1,3])