ID
41334
Beskrivning
DELCODE is conducted by DZNE, the German Center for Neurodegenerative Diseases within the Helmholtz Association. The following information was taken from https://www.dzne.de/en/research/studies/clinical-studies/delcode/. Background and aims: One of the important aims of research into Alzheimer's is to find ways of detecting the disease early – if at all possible, as soon as the first minor symptoms appear, or even before any symptoms at all have appeared. Such detection capabilities are the necessary basis for development of therapies that can be applied at such early stages in the disease. Recent research indicates that such therapies could be more effective than therapies initiated during the disease's later stages. Over a period of several years, the DELCODE study is studying persons in early stages of the disease, along with various risk groups. The research is aimed at the development of procedures for characterizing early stages of the disease, at improving prediction of the course of the disease and at identifying new markers for early diagnosis of Alzheimer's-related dementia. Overview: DELCODE is set up to run for an initial period of three years, and to include a total of 1,000 study participants, who will be examined on a yearly basis. The group of participants will include persons with no complaints (healthy control subjects), patients with slight memory impairment or mild dementia and first-degree relatives of patients with diagnosed Alzheimer's disease. The minimum age for participants is 60. Course of the study: The examinations in the framework of the study will include a comprehensive interview carried out by a study investigator, a detailed neuropsychological examination (testing of memory functions and other areas of cognitive performance), a blood test and a cranial MRI scan. Optionally, subject to the study participant's consent in each case, a lumbar puncture (collection of cerebrospinal fluid) will be carried out." For more information (e.g. principle investigator and study coordination), please visit the above link or https://www.dzne.de. This document contains the Neuropsychological testing form. It has to be filled in for baseline and for all follow-ups. This form contains several questionnaires: Verbal Fluency, Wechsler Memory Scale (WMS-IV, WMS-R), Symbol Digit Modalitites, Incidental learning, Watch drawing, Trail Making Test, Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog13), Free and Cued Selective Reminding Test with immediate Recall (FCSRT-IR), Face Name Test, Arrow test and MWT-B. Due to potential copyright on the questionnaires ADAS-Cog13 and FCSRT-IR included in the DZNE DELCODE protocol, these quetionnaire will only be included as (sub-)scores/text result items in this version of the DELCODE forms. The respective score items will have a comment in their descriptions about this to distinguish them from score items that were already defined like that by DZNE.
Länk
https://www.dzne.de/en/research/studies/clinical-studies/delcode/
Nyckelord
Versioner (2)
- 2020-08-28 2020-08-28 -
- 2020-08-31 2020-08-31 - Sarah Riepenhausen
Rättsinnehavare
DZNE
Uppladdad den
28 augusti 2020
DOI
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Licens
Creative Commons BY-NC 4.0
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DELCODE: DZNE – Longitudinal Cognitive Impairment and Dementia Study
Neuropsychological testing (Neuropsychologische Testung)
- StudyEvent: ODM
Similar models
Neuropsychological testing (Neuropsychologische Testung)
- StudyEvent: ODM
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