ID

40321

Descripción

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension; ODM derived from: https://clinicaltrials.gov/show/NCT01996449

Link

https://clinicaltrials.gov/show/NCT01996449

Palabras clave

Versiones (1)
  1. 8/4/20 8/4/20 -
Titular de derechos de autor

See clinicaltrials.gov

Subido en

8 de abril de 2020

DOI

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Licencia

Creative Commons BY 4.0
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Eligibility Hypertension NCT01996449

Inglés

Eligibility Hypertension NCT01996449

1 formularios  
Inclusion Criteria
Descripción

Inclusion Criteria

Alias
UMLS CUI
C1512693
experiments will be performed on 3 groups of nondiabetic human subjects:
Descripción

Research study Performed | Study Subject Without Diabetes Mellitus | Study Subject Groups Quantity

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0681814
UMLS CUI [1,2]
C0884358
UMLS CUI [2,1]
C0681850
UMLS CUI [2,2]
C0332288
UMLS CUI [2,3]
C0011849
UMLS CUI [3,1]
C0681850
UMLS CUI [3,2]
C0441833
UMLS CUI [3,3]
C1265611
1) stage i (140-159/90-99 mmhg) subjects with essential hypertension.
Descripción

Essential Hypertension Stage | Blood pressure determination

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0085580
UMLS CUI [1,2]
C0699749
UMLS CUI [2]
C0005824
2) stage i hypertensive subjects with primary aldosteronism
Descripción

Hypertensive disease Stage | Conn Syndrome

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0020538
UMLS CUI [1,2]
C0699749
UMLS CUI [2]
C1384514
3) normotensive controls.
Descripción

Normal blood pressure Control

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C2712122
UMLS CUI [1,2]
C2587213
Exclusion Criteria
Descripción

Exclusion Criteria

Alias
UMLS CUI
C0680251
1) any evidence of cardiopulmonary disease, left ventricular hypertrophy or systolic dysfunction by echocardiography.
Descripción

Cor pulmonale Echocardiography | Left Ventricular Hypertrophy Echocardiography | Left ventricular systolic dysfunction Echocardiography

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0034072
UMLS CUI [1,2]
C0013516
UMLS CUI [2,1]
C0149721
UMLS CUI [2,2]
C0013516
UMLS CUI [3,1]
C1277187
UMLS CUI [3,2]
C0013516
2) blood pressure averaging ≥160/100 mmhg
Descripción

Blood pressure determination Average

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0005824
UMLS CUI [1,2]
C1510992
3) estimated glomerular filtration rate (egfr) < 90 ml/min/1.73m2
Descripción

Estimated Glomerular Filtration Rate

Tipo de datos

boolean

Alias
UMLS CUI [1]
C3811844
4) diabetes mellitus or other systemic illness
Descripción

Diabetes Mellitus | Systemic disease

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0011849
UMLS CUI [2]
C0442893
5) pregnancy
Descripción

Pregnancy

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0032961
6) hypersensitivity to nitroprusside, phenylephrine, amlodipine or eplerenone
Descripción

NITROPRUSSIDE ALLERGY | Phenylephrine allergy | Amlodipine allergy | Hypersensitivity Eplerenone

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0746910
UMLS CUI [2]
C0570949
UMLS CUI [3]
C0570921
UMLS CUI [4,1]
C0020517
UMLS CUI [4,2]
C0961485
7) any history of substance abuse or current cigarette use
Descripción

Substance Use Disorders | Cigarette use

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0038586
UMLS CUI [2]
C0694535
8) any history of psychiatric illness
Descripción

Mental disorders

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0004936
9) history of malignancy
Descripción

History of malignant neoplasm

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0455471
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Similar models

Eligibility Hypertension NCT01996449

1 formularios
Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
C1512693 (UMLS CUI)
Research study Performed | Study Subject Without Diabetes Mellitus | Study Subject Groups Quantity
Item
experiments will be performed on 3 groups of nondiabetic human subjects:
boolean
C0681814 (UMLS CUI [1,1])
C0884358 (UMLS CUI [1,2])
C0681850 (UMLS CUI [2,1])
C0332288 (UMLS CUI [2,2])
C0011849 (UMLS CUI [2,3])
C0681850 (UMLS CUI [3,1])
C0441833 (UMLS CUI [3,2])
C1265611 (UMLS CUI [3,3])
Essential Hypertension Stage | Blood pressure determination
Item
1) stage i (140-159/90-99 mmhg) subjects with essential hypertension.
boolean
C0085580 (UMLS CUI [1,1])
C0699749 (UMLS CUI [1,2])
C0005824 (UMLS CUI [2])
Hypertensive disease Stage | Conn Syndrome
Item
2) stage i hypertensive subjects with primary aldosteronism
boolean
C0020538 (UMLS CUI [1,1])
C0699749 (UMLS CUI [1,2])
C1384514 (UMLS CUI [2])
Normal blood pressure Control
Item
3) normotensive controls.
boolean
C2712122 (UMLS CUI [1,1])
C2587213 (UMLS CUI [1,2])
Item Group
C0680251 (UMLS CUI)
Cor pulmonale Echocardiography | Left Ventricular Hypertrophy Echocardiography | Left ventricular systolic dysfunction Echocardiography
Item
1) any evidence of cardiopulmonary disease, left ventricular hypertrophy or systolic dysfunction by echocardiography.
boolean
C0034072 (UMLS CUI [1,1])
C0013516 (UMLS CUI [1,2])
C0149721 (UMLS CUI [2,1])
C0013516 (UMLS CUI [2,2])
C1277187 (UMLS CUI [3,1])
C0013516 (UMLS CUI [3,2])
Blood pressure determination Average
Item
2) blood pressure averaging ≥160/100 mmhg
boolean
C0005824 (UMLS CUI [1,1])
C1510992 (UMLS CUI [1,2])
Estimated Glomerular Filtration Rate
Item
3) estimated glomerular filtration rate (egfr) < 90 ml/min/1.73m2
boolean
C3811844 (UMLS CUI [1])
Diabetes Mellitus | Systemic disease
Item
4) diabetes mellitus or other systemic illness
boolean
C0011849 (UMLS CUI [1])
C0442893 (UMLS CUI [2])
Pregnancy
Item
5) pregnancy
boolean
C0032961 (UMLS CUI [1])
NITROPRUSSIDE ALLERGY | Phenylephrine allergy | Amlodipine allergy | Hypersensitivity Eplerenone
Item
6) hypersensitivity to nitroprusside, phenylephrine, amlodipine or eplerenone
boolean
C0746910 (UMLS CUI [1])
C0570949 (UMLS CUI [2])
C0570921 (UMLS CUI [3])
C0020517 (UMLS CUI [4,1])
C0961485 (UMLS CUI [4,2])
Substance Use Disorders | Cigarette use
Item
7) any history of substance abuse or current cigarette use
boolean
C0038586 (UMLS CUI [1])
C0694535 (UMLS CUI [2])
Mental disorders
Item
8) any history of psychiatric illness
boolean
C0004936 (UMLS CUI [1])
History of malignant neoplasm
Item
9) history of malignancy
boolean
C0455471 (UMLS CUI [1])
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