ID
40307
Beskrivning
DELCODE is conducted by DZNE, the German Center for Neurodegenerative Diseases within the Helmholtz Association. The following information was taken from https://www.dzne.de/en/research/studies/clinical-studies/delcode/. Background and aims: One of the important aims of research into Alzheimer's is to find ways of detecting the disease early – if at all possible, as soon as the first minor symptoms appear, or even before any symptoms at all have appeared. Such detection capabilities are the necessary basis for development of therapies that can be applied at such early stages in the disease. Recent research indicates that such therapies could be more effective than therapies initiated during the disease's later stages. Over a period of several years, the DELCODE study is studying persons in early stages of the disease, along with various risk groups. The research is aimed at the development of procedures for characterizing early stages of the disease, at improving prediction of the course of the disease and at identifying new markers for early diagnosis of Alzheimer's-related dementia. Overview: DELCODE is set up to run for an initial period of three years, and to include a total of 1,000 study participants, who will be examined on a yearly basis. The group of participants will include persons with no complaints (healthy control subjects), patients with slight memory impairment or mild dementia and first-degree relatives of patients with diagnosed Alzheimer's disease. The minimum age for participants is 60. Course of the study: The examinations in the framework of the study will include a comprehensive interview carried out by a study investigator, a detailed neuropsychological examination (testing of memory functions and other areas of cognitive performance), a blood test and a cranial MRI scan. Optionally, subject to the study participant's consent in each case, a lumbar puncture (collection of cerebrospinal fluid) will be carried out." For more information (e.g. principle investigator and study coordination), please visit the above link or https://www.dzne.de. This document contains the Diagnosis criteria Diffuse Lewy Body Disease form. It has to be filled in if a Diffuse Lewy Body Disease is diagnosed.
Länk
https://www.dzne.de/en/research/studies/clinical-studies/delcode/
Nyckelord
Versioner (1)
- 2020-04-02 2020-04-02 -
Rättsinnehavare
DZNE
Uppladdad den
2 april 2020
DOI
För en begäran logga in.
Licens
Creative Commons BY-NC 4.0
Modellkommentarer :
Här kan du kommentera modellen. Med hjälp av pratbubblor i Item-grupperna och Item kan du lägga in specifika kommentarer.
Itemgroup-kommentar för :
Item-kommentar för :
Du måste vara inloggad för att kunna ladda ner formulär. Var vänlig logga in eller registrera dig utan kostnad.
DELCODE: DZNE – Longitudinal Cognitive Impairment and Dementia Study
Diagnosis criteria Diffuse Lewy Body Disease (Diagnosekriterien Diffuse Lewykörperchen Erkrankung (DLB))
Beskrivning
Diffuse Lewykörperchen Erkrankung (DLB)
Alias
- UMLS CUI-1
- C0205219
- UMLS CUI-2
- C0752347
Beskrivning
DLB: Zentrales Kriterium
Alias
- UMLS CUI-1
- C0205219
- UMLS CUI-2
- C0752347
- UMLS CUI-3
- C0243161
- UMLS CUI-4
- C0205225
Beskrivning
Dementia with impairment of daily life (in early stage of disease persistent memory impairment possible while in progression of disease usually occurs. Impairment of attention, executive functions, visuospatial ability)
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0497327
- UMLS CUI [1,2]
- C0205329
- UMLS CUI [1,3]
- C0338656
- UMLS CUI [2,1]
- C0497327
- UMLS CUI [2,2]
- C0001288
- UMLS CUI [2,3]
- C0221099
- UMLS CUI [3,1]
- C2363430
- UMLS CUI [3,2]
- C0205322
- UMLS CUI [3,3]
- C0233794
- UMLS CUI [3,4]
- C0332149
- UMLS CUI [4,1]
- C0242656
- UMLS CUI [4,2]
- C0205322
- UMLS CUI [4,3]
- C0233794
- UMLS CUI [4,4]
- C3888388
- UMLS CUI [5]
- C2678119
- UMLS CUI [6]
- C2921138
Beskrivning
DLB: Hauptkriterien
Alias
- UMLS CUI-1
- C0205219
- UMLS CUI-2
- C0752347
- UMLS CUI-3
- C0243161
- UMLS CUI-4
- C1542147
Beskrivning
Fluctuations in cognition, especially in attention
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0231239
- UMLS CUI [1,2]
- C0009240
- UMLS CUI [2,1]
- C0231239
- UMLS CUI [2,2]
- C0004268
Beskrivning
Recurring visual hallucinations (typically person character and detailed)
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0233763
- UMLS CUI [1,2]
- C2945760
- UMLS CUI [1,3]
- C3538928
- UMLS CUI [1,4]
- C0205431
- UMLS CUI [2,1]
- C0233763
- UMLS CUI [2,2]
- C2945760
- UMLS CUI [2,3]
- C3538928
- UMLS CUI [2,4]
- C0439855
Beskrivning
Spontaneous Parkinson symptoms
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0205359
- UMLS CUI [1,2]
- C0030567
- UMLS CUI [1,3]
- C1457887
Beskrivning
DLB: Zusatzkriterien
Alias
- UMLS CUI-1
- C0205219
- UMLS CUI-2
- C0752347
- UMLS CUI-3
- C0243161
- UMLS CUI-4
- C1524062
Beskrivning
REM Sleep Behavior Disorder
Datatyp
integer
Alias
- UMLS CUI [1]
- C0751772
Beskrivning
Serious side effects due to the use of neuroleptics
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0041755
- UMLS CUI [1,2]
- C0205082
- UMLS CUI [1,3]
- C0040615
Beskrivning
Reduced dopamine transporter ligand storage in basal ganglia (SPECT/PET)
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0183126
- UMLS CUI [1,2]
- C0114838
- UMLS CUI [1,3]
- C0023688
- UMLS CUI [1,4]
- C1698986
- UMLS CUI [1,5]
- C0392756
- UMLS CUI [1,6]
- C0004781
- UMLS CUI [2,1]
- C0032743
- UMLS CUI [2,2]
- C0114838
- UMLS CUI [2,3]
- C0023688
- UMLS CUI [2,4]
- C1698986
- UMLS CUI [2,5]
- C0392756
- UMLS CUI [2,6]
- C0004781
Beskrivning
Occurrence of dementia before/ simultaneously parkinson symptoms
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C2745955
- UMLS CUI [1,2]
- C0497327
- UMLS CUI [1,3]
- C0332152
- UMLS CUI [1,4]
- C0030567
- UMLS CUI [1,5]
- C1457887
- UMLS CUI [2,1]
- C2745955
- UMLS CUI [2,2]
- C0497327
- UMLS CUI [2,3]
- C0521115
- UMLS CUI [2,4]
- C0030567
- UMLS CUI [2,5]
- C1457887
Beskrivning
(Item 1 und mind. ein Merkmale aus 2‐4 sowie mind. 1 Merkmal aus 5‐7 treffen zu; Item 8 ist erfüllt)
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0752347
- UMLS CUI [1,2]
- C0332148
Beskrivning
(Item 1 und mind. ein Merkmal aus 5‐7 treffen zu, Item 8 ist erfüllt)
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0752347
- UMLS CUI [1,2]
- C0332149
- UMLS CUI [1,3]
- C0011900
Beskrivning
Unterstützende Merkmale ohne nachweisliche diagnostische Spezifität
Alias
- UMLS CUI-1
- C4684795
- UMLS CUI-2
- C0243161
- UMLS CUI-3
- C1298908
- UMLS CUI-4
- C0456369
- UMLS CUI-5
- C1511884
Beskrivning
Frequent falls and syncopes
Datatyp
integer
Alias
- UMLS CUI [1]
- C0850703
- UMLS CUI [2,1]
- C0332183
- UMLS CUI [2,2]
- C0039070
Beskrivning
Transient loss of consciousness
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0205374
- UMLS CUI [1,2]
- C0041657
Beskrivning
Severe autonomic dysfunction
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C3277919
- UMLS CUI [1,2]
- C0205082
Beskrivning
Hallucinations in other modalities
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0018524
- UMLS CUI [1,2]
- C0695347
- UMLS CUI [1,3]
- C0205394
Beskrivning
Delusion
Datatyp
integer
Alias
- UMLS CUI [1]
- C0011253
Beskrivning
Depression
Datatyp
integer
Alias
- UMLS CUI [1]
- C0011581
Beskrivning
Slightly change in medial temporal lobe (CT/MRT)
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0039485
- UMLS CUI [1,2]
- C0205098
- UMLS CUI [1,3]
- C1298908
- UMLS CUI [1,4]
- C2826293
- UMLS CUI [1,5]
- C1879646
- UMLS CUI [1,6]
- C0040405
- UMLS CUI [2,1]
- C0039485
- UMLS CUI [2,2]
- C0205098
- UMLS CUI [2,3]
- C1298908
- UMLS CUI [2,4]
- C2826293
- UMLS CUI [2,5]
- C1879646
- UMLS CUI [2,6]
- C0024485
Beskrivning
Low uptake in SPECT/PET perfusion scan with reduced occipital activity
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C2094594
- UMLS CUI [1,2]
- C0205251
- UMLS CUI [1,3]
- C0243144
- UMLS CUI [2,1]
- C2094594
- UMLS CUI [2,2]
- C0392756
- UMLS CUI [2,3]
- C1184145
- UMLS CUI [2,4]
- C0443158
- UMLS CUI [3,1]
- C0183126
- UMLS CUI [3,2]
- C4523908
- UMLS CUI [3,3]
- C0205251
- UMLS CUI [3,4]
- C0243144
- UMLS CUI [4,1]
- C0183126
- UMLS CUI [4,2]
- C4523908
- UMLS CUI [4,3]
- C0392756
- UMLS CUI [4,4]
- C1184145
- UMLS CUI [4,5]
- C0443158
Beskrivning
Abnormally low uptake in the MIBG Myocardial Scintigraphy
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C1704258
- UMLS CUI [1,2]
- C0205251
- UMLS CUI [1,3]
- C0243144
- UMLS CUI [1,4]
- C2229074
Beskrivning
Prominent slow wave activity in EEG with temporal transient sharp waves
Datatyp
integer
Alias
- UMLS CUI [1]
- C2206519
- UMLS CUI [2]
- C3670521
Beskrivning
Befunde, die die Diagnose wenig wahrscheinlich machen
Alias
- UMLS CUI-1
- C0011900
- UMLS CUI-2
- C1298908
- UMLS CUI-3
- C0332148
Beskrivning
History of a brain injury
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0262926
- UMLS CUI [1,2]
- C0270611
- UMLS CUI [2,1]
- C0262926
- UMLS CUI [2,2]
- C0038454
Beskrivning
Other diseases
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C2359476
- UMLS CUI [1,2]
- C0681841
- UMLS CUI [1,3]
- C2987487
Beskrivning
First occurrence of parkinson symptoms in severe stage of dementia
Datatyp
integer
Alias
- UMLS CUI [1,1]
- C0205435
- UMLS CUI [1,2]
- C2745955
- UMLS CUI [1,3]
- C0030567
- UMLS CUI [1,4]
- C1457887
- UMLS CUI [1,5]
- C0497327
- UMLS CUI [1,6]
- C0699749
- UMLS CUI [1,7]
- C0205082
Similar models
Diagnosis criteria Diffuse Lewy Body Disease (Diagnosekriterien Diffuse Lewykörperchen Erkrankung (DLB))
C0752347 (UMLS CUI-2)
C0679228 (UMLS CUI [1,2])
C3846158 (UMLS CUI [1,3])
C0752347 (UMLS CUI-2)
C0243161 (UMLS CUI-3)
C0205225 (UMLS CUI-4)
C0205329 (UMLS CUI [1,2])
C0338656 (UMLS CUI [1,3])
C0497327 (UMLS CUI [2,1])
C0001288 (UMLS CUI [2,2])
C0221099 (UMLS CUI [2,3])
C2363430 (UMLS CUI [3,1])
C0205322 (UMLS CUI [3,2])
C0233794 (UMLS CUI [3,3])
C0332149 (UMLS CUI [3,4])
C0242656 (UMLS CUI [4,1])
C0205322 (UMLS CUI [4,2])
C0233794 (UMLS CUI [4,3])
C3888388 (UMLS CUI [4,4])
C2678119 (UMLS CUI [5])
C2921138 (UMLS CUI [6])
C0752347 (UMLS CUI-2)
C0243161 (UMLS CUI-3)
C1542147 (UMLS CUI-4)
C0009240 (UMLS CUI [1,2])
C0231239 (UMLS CUI [2,1])
C0004268 (UMLS CUI [2,2])
C2945760 (UMLS CUI [1,2])
C3538928 (UMLS CUI [1,3])
C0205431 (UMLS CUI [1,4])
C0233763 (UMLS CUI [2,1])
C2945760 (UMLS CUI [2,2])
C3538928 (UMLS CUI [2,3])
C0439855 (UMLS CUI [2,4])
C0030567 (UMLS CUI [1,2])
C1457887 (UMLS CUI [1,3])
C0752347 (UMLS CUI-2)
C0243161 (UMLS CUI-3)
C1524062 (UMLS CUI-4)
C0205082 (UMLS CUI [1,2])
C0040615 (UMLS CUI [1,3])
C0114838 (UMLS CUI [1,2])
C0023688 (UMLS CUI [1,3])
C1698986 (UMLS CUI [1,4])
C0392756 (UMLS CUI [1,5])
C0004781 (UMLS CUI [1,6])
C0032743 (UMLS CUI [2,1])
C0114838 (UMLS CUI [2,2])
C0023688 (UMLS CUI [2,3])
C1698986 (UMLS CUI [2,4])
C0392756 (UMLS CUI [2,5])
C0004781 (UMLS CUI [2,6])
C0497327 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,3])
C0030567 (UMLS CUI [1,4])
C1457887 (UMLS CUI [1,5])
C2745955 (UMLS CUI [2,1])
C0497327 (UMLS CUI [2,2])
C0521115 (UMLS CUI [2,3])
C0030567 (UMLS CUI [2,4])
C1457887 (UMLS CUI [2,5])
C0332148 (UMLS CUI [1,2])
C0332149 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
C0243161 (UMLS CUI-2)
C1298908 (UMLS CUI-3)
C0456369 (UMLS CUI-4)
C1511884 (UMLS CUI-5)
C0332183 (UMLS CUI [2,1])
C0039070 (UMLS CUI [2,2])
C0041657 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,2])
C0695347 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0205098 (UMLS CUI [1,2])
C1298908 (UMLS CUI [1,3])
C2826293 (UMLS CUI [1,4])
C1879646 (UMLS CUI [1,5])
C0040405 (UMLS CUI [1,6])
C0039485 (UMLS CUI [2,1])
C0205098 (UMLS CUI [2,2])
C1298908 (UMLS CUI [2,3])
C2826293 (UMLS CUI [2,4])
C1879646 (UMLS CUI [2,5])
C0024485 (UMLS CUI [2,6])
C0205251 (UMLS CUI [1,2])
C0243144 (UMLS CUI [1,3])
C2094594 (UMLS CUI [2,1])
C0392756 (UMLS CUI [2,2])
C1184145 (UMLS CUI [2,3])
C0443158 (UMLS CUI [2,4])
C0183126 (UMLS CUI [3,1])
C4523908 (UMLS CUI [3,2])
C0205251 (UMLS CUI [3,3])
C0243144 (UMLS CUI [3,4])
C0183126 (UMLS CUI [4,1])
C4523908 (UMLS CUI [4,2])
C0392756 (UMLS CUI [4,3])
C1184145 (UMLS CUI [4,4])
C0443158 (UMLS CUI [4,5])
C0205251 (UMLS CUI [1,2])
C0243144 (UMLS CUI [1,3])
C2229074 (UMLS CUI [1,4])
C3670521 (UMLS CUI [2])
C1298908 (UMLS CUI-2)
C0332148 (UMLS CUI-3)
C0270611 (UMLS CUI [1,2])
C0262926 (UMLS CUI [2,1])
C0038454 (UMLS CUI [2,2])
C0681841 (UMLS CUI [1,2])
C2987487 (UMLS CUI [1,3])
C2745955 (UMLS CUI [1,2])
C0030567 (UMLS CUI [1,3])
C1457887 (UMLS CUI [1,4])
C0497327 (UMLS CUI [1,5])
C0699749 (UMLS CUI [1,6])
C0205082 (UMLS CUI [1,7])