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ID

38609

Descrizione

Evaluation Of The Efficacy Of The Combination Of Axitinib With Pemetrexed And Cisplatin In The Treatment Of Non-Squamous Non-Small Cell Lung Cancer; ODM derived from: https://clinicaltrials.gov/show/NCT00768755

collegamento

https://clinicaltrials.gov/show/NCT00768755

Keywords

versioni (1)
  1. 28/10/19 28/10/19 -
Titolare del copyright

See clinicaltrials.gov

Caricato su

28 ottobre 2019

DOI

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Licenza

Creative Commons BY 4.0
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    Eligibility Carcinoma, Non-Small Cell Lung NCT00768755

    Inglese

    Eligibility Carcinoma, Non-Small Cell Lung NCT00768755

    1 moduli  
    Inclusion Criteria
    Descrizione

    Inclusion Criteria

    Alias
    UMLS CUI
    C1512693
    histologically or cytologically confirmed diagnosis of adeno-, large cell or bronchioalveolar non-small cell lung cancer
    Descrizione

    Adenocarcinoma of lung | Large cell carcinoma of lung | Bronchioloalveolar Non-Small Cell Lung Carcinoma

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0152013
    UMLS CUI [2]
    C0345958
    UMLS CUI [3,1]
    C0007120
    UMLS CUI [3,2]
    C0007131
    cytologic specimens for diagnosis or for cell type classification must have been obtained from bronchial brushings or washings or from needle aspiration of a defined lesion. sputum cytology alone will not be acceptable for diagnosis or for cell type classification.
    Descrizione

    Cytologic material Cell type Classification | Bronchial brush biopsy | Bronchial washing | Lesion Fine needle aspiration

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1,1]
    C0225355
    UMLS CUI [1,2]
    C0449475
    UMLS CUI [1,3]
    C0008902
    UMLS CUI [2]
    C2370811
    UMLS CUI [3]
    C0396473
    UMLS CUI [4,1]
    C0221198
    UMLS CUI [4,2]
    C1510483
    patients with mixed nsclc with predominantly squamous cell carcinoma should be classified as squamous and thus do not qualify for this study.
    Descrizione

    Non-Small Cell Lung Carcinoma Mixed Ineligible | Squamous non-small cell lung cancer Ineligible

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1,1]
    C0007131
    UMLS CUI [1,2]
    C0205430
    UMLS CUI [1,3]
    C1512714
    UMLS CUI [2,1]
    C4509816
    UMLS CUI [2,2]
    C1512714
    stage iiib with malignant effusion (with cytologic confirmation of malignant pleural or pericardial effusion), stage iv, or recurrent disease after definitive loco-regional therapy.
    Descrizione

    TNM clinical staging | Pleural Effusion, Malignant | Malignant pericardial effusion | Recurrent disease | Status post Therapy Locoregional

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C3258246
    UMLS CUI [2]
    C0080032
    UMLS CUI [3]
    C0220655
    UMLS CUI [4]
    C0277556
    UMLS CUI [5,1]
    C0231290
    UMLS CUI [5,2]
    C0087111
    UMLS CUI [5,3]
    C1947913
    candidate for primary treatment with cisplatin and pemetrexed
    Descrizione

    Patient Appropriate Primary treatment | Cisplatin | pemetrexed

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1,1]
    C0030705
    UMLS CUI [1,2]
    C1548787
    UMLS CUI [1,3]
    C1708063
    UMLS CUI [2]
    C0008838
    UMLS CUI [3]
    C0210657
    Exclusion Criteria
    Descrizione

    Exclusion Criteria

    Alias
    UMLS CUI
    C0680251
    any histological/cytological evidence of predominantly squamous nsclc.
    Descrizione

    Squamous non-small cell lung cancer predominant

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1,1]
    C4509816
    UMLS CUI [1,2]
    C1542147
    small cell or carcinoid lung cancer patients are also ineligible.
    Descrizione

    Small cell carcinoma of lung | Carcinoid tumor of lung

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C0149925
    UMLS CUI [2]
    C0280089
    nsclc that cannot be classified as one of the eligible histologies (adenocarcinoma, large cell or bronchioalveolar).
    Descrizione

    Non-Small Cell Lung Carcinoma Without Histology Eligible

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1,1]
    C0007131
    UMLS CUI [1,2]
    C0332288
    UMLS CUI [1,3]
    C4048239
    UMLS CUI [1,4]
    C1548635
    prior systemic therapy for stage iiib (with malignant effusion), stage iv, or recurrent nsclc. (prior treatment with systemic therapy as adjuvant chemotherapy or in conjunction with radiotherapy for stage ii or iii nsclc is permitted if the last dose of chemotherapy was completed 12 months or more prior to randomization).
    Descrizione

    Systemic therapy TNM clinical staging | Systemic therapy Malignant Effusion | Systemic therapy Non-small cell lung cancer recurrent

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1,1]
    C1515119
    UMLS CUI [1,2]
    C3258246
    UMLS CUI [2,1]
    C1515119
    UMLS CUI [2,2]
    C0080032
    UMLS CUI [3,1]
    C1515119
    UMLS CUI [3,2]
    C0278517
    prior treatment with a vegf or vegfr inhibitor.
    Descrizione

    VEGF Inhibitor | VEGFR Inhibitor

    Tipo di dati

    boolean

    Alias
    UMLS CUI [1]
    C4521299
    UMLS CUI [2]
    C2985521
    Ritorna all'inizio della pagina

    Similar models

    Eligibility Carcinoma, Non-Small Cell Lung NCT00768755

    1 moduli
    Name
    genere
    Description | Question | Decode (Coded Value)
    Tipo di dati
    Alias
    Item Group
    C1512693 (UMLS CUI)
    Adenocarcinoma of lung | Large cell carcinoma of lung | Bronchioloalveolar Non-Small Cell Lung Carcinoma
    Item
    histologically or cytologically confirmed diagnosis of adeno-, large cell or bronchioalveolar non-small cell lung cancer
    boolean
    C0152013 (UMLS CUI [1])
    C0345958 (UMLS CUI [2])
    C0007120 (UMLS CUI [3,1])
    C0007131 (UMLS CUI [3,2])
    Cytologic material Cell type Classification | Bronchial brush biopsy | Bronchial washing | Lesion Fine needle aspiration
    Item
    cytologic specimens for diagnosis or for cell type classification must have been obtained from bronchial brushings or washings or from needle aspiration of a defined lesion. sputum cytology alone will not be acceptable for diagnosis or for cell type classification.
    boolean
    C0225355 (UMLS CUI [1,1])
    C0449475 (UMLS CUI [1,2])
    C0008902 (UMLS CUI [1,3])
    C2370811 (UMLS CUI [2])
    C0396473 (UMLS CUI [3])
    C0221198 (UMLS CUI [4,1])
    C1510483 (UMLS CUI [4,2])
    Non-Small Cell Lung Carcinoma Mixed Ineligible | Squamous non-small cell lung cancer Ineligible
    Item
    patients with mixed nsclc with predominantly squamous cell carcinoma should be classified as squamous and thus do not qualify for this study.
    boolean
    C0007131 (UMLS CUI [1,1])
    C0205430 (UMLS CUI [1,2])
    C1512714 (UMLS CUI [1,3])
    C4509816 (UMLS CUI [2,1])
    C1512714 (UMLS CUI [2,2])
    TNM clinical staging | Pleural Effusion, Malignant | Malignant pericardial effusion | Recurrent disease | Status post Therapy Locoregional
    Item
    stage iiib with malignant effusion (with cytologic confirmation of malignant pleural or pericardial effusion), stage iv, or recurrent disease after definitive loco-regional therapy.
    boolean
    C3258246 (UMLS CUI [1])
    C0080032 (UMLS CUI [2])
    C0220655 (UMLS CUI [3])
    C0277556 (UMLS CUI [4])
    C0231290 (UMLS CUI [5,1])
    C0087111 (UMLS CUI [5,2])
    C1947913 (UMLS CUI [5,3])
    Patient Appropriate Primary treatment | Cisplatin | pemetrexed
    Item
    candidate for primary treatment with cisplatin and pemetrexed
    boolean
    C0030705 (UMLS CUI [1,1])
    C1548787 (UMLS CUI [1,2])
    C1708063 (UMLS CUI [1,3])
    C0008838 (UMLS CUI [2])
    C0210657 (UMLS CUI [3])
    Item Group
    C0680251 (UMLS CUI)
    Squamous non-small cell lung cancer predominant
    Item
    any histological/cytological evidence of predominantly squamous nsclc.
    boolean
    C4509816 (UMLS CUI [1,1])
    C1542147 (UMLS CUI [1,2])
    Small cell carcinoma of lung | Carcinoid tumor of lung
    Item
    small cell or carcinoid lung cancer patients are also ineligible.
    boolean
    C0149925 (UMLS CUI [1])
    C0280089 (UMLS CUI [2])
    Non-Small Cell Lung Carcinoma Without Histology Eligible
    Item
    nsclc that cannot be classified as one of the eligible histologies (adenocarcinoma, large cell or bronchioalveolar).
    boolean
    C0007131 (UMLS CUI [1,1])
    C0332288 (UMLS CUI [1,2])
    C4048239 (UMLS CUI [1,3])
    C1548635 (UMLS CUI [1,4])
    Systemic therapy TNM clinical staging | Systemic therapy Malignant Effusion | Systemic therapy Non-small cell lung cancer recurrent
    Item
    prior systemic therapy for stage iiib (with malignant effusion), stage iv, or recurrent nsclc. (prior treatment with systemic therapy as adjuvant chemotherapy or in conjunction with radiotherapy for stage ii or iii nsclc is permitted if the last dose of chemotherapy was completed 12 months or more prior to randomization).
    boolean
    C1515119 (UMLS CUI [1,1])
    C3258246 (UMLS CUI [1,2])
    C1515119 (UMLS CUI [2,1])
    C0080032 (UMLS CUI [2,2])
    C1515119 (UMLS CUI [3,1])
    C0278517 (UMLS CUI [3,2])
    VEGF Inhibitor | VEGFR Inhibitor
    Item
    prior treatment with a vegf or vegfr inhibitor.
    boolean
    C4521299 (UMLS CUI [1])
    C2985521 (UMLS CUI [2])
    Ritorna all'inizio della pagina 

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