ID

38026

Descrizione

A Study of Pertuzumab in Combination With Trastuzumab Plus an Aromatase Inhibitor in Patients With Hormone Receptor-Positive, Metastatic HER2-positive Breast Cancer; ODM derived from: https://clinicaltrials.gov/show/NCT01491737

collegamento

https://clinicaltrials.gov/show/NCT01491737

Keywords

versioni (1)
  1. 09/09/19 09/09/19 -
Titolare del copyright

See clinicaltrials.gov

Caricato su

9 settembre 2019

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY 4.0
Commenti del modello :

Puoi commentare il modello dati qui. Tramite i fumetti nei gruppi di articoli e articoli è possibile aggiungere commenti a quelli in modo specifico.

Torna ai commenti del modello
Commenti del gruppo di articoli per :

Commenti dell'articolo per :

Per scaricare i modelli di dati devi essere registrato. Per favore accesso o registrati GRATIS.

Eligibility Breast Cancer NCT01491737

Inglese

Eligibility Breast Cancer NCT01491737

1 moduli  
Inclusion Criteria
Descrizione

Inclusion Criteria

Alias
UMLS CUI
C1512693
female adult patients, >/=18 years of age
Descrizione

Gender | Adult | Age

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0079399
UMLS CUI [2]
C0001675
UMLS CUI [3]
C0001779
patients with her2-positive and hormone receptor-positive advanced metastatic or locally advanced breast cancer
Descrizione

Secondary malignant neoplasm of female breast Advanced HER2 Positive | Secondary malignant neoplasm of female breast Advanced Hormone Receptor Positive | Locally advanced breast cancer HER2 Positive | Locally advanced breast cancer Hormone Receptor Positive

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0346993
UMLS CUI [1,2]
C0205179
UMLS CUI [1,3]
C2348909
UMLS CUI [2,1]
C0346993
UMLS CUI [2,2]
C0205179
UMLS CUI [2,3]
C0019929
UMLS CUI [2,4]
C1514241
UMLS CUI [3,1]
C3495949
UMLS CUI [3,2]
C2348909
UMLS CUI [4,1]
C3495949
UMLS CUI [4,2]
C0019929
UMLS CUI [4,3]
C1514241
post-menopausal status over 1 year
Descrizione

Postmenopausal state

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0232970
her2-positive as assessed by local laboratory on primary or metastatic tumor
Descrizione

Primary tumor HER2 Positive | Neoplasm Metastasis HER2 Positive

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0677930
UMLS CUI [1,2]
C2348909
UMLS CUI [2,1]
C0027627
UMLS CUI [2,2]
C2348909
hormone-receptor positive defined as er-positive and/or pgr-positive
Descrizione

Hormone Receptor Positive Definition | Estrogen receptor positive | Progesterone receptor positive

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0019929
UMLS CUI [1,2]
C1514241
UMLS CUI [1,3]
C1704788
UMLS CUI [2]
C0279754
UMLS CUI [3]
C0279759
at least one measurable lesion and/or non-measurable disease according to response evaluation criteria in solid tumors (recist)
Descrizione

Measurable lesion Quantity | Non-Measurable Lesion Quantity

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1513041
UMLS CUI [1,2]
C1265611
UMLS CUI [2,1]
C1334988
UMLS CUI [2,2]
C1265611
Exclusion Criteria
Descrizione

Exclusion Criteria

Alias
UMLS CUI
C0680251
previous treatment with anti-her2 agents for breast cancer, except trastuzumab and/or lapatinib in the neoadjuvant or adjuvant setting
Descrizione

Prior Therapy Breast Carcinoma | HER2 Receptor Antagonist | Exception Trastuzumab Neoadjuvant Therapy | Exception Lapatinib Neoadjuvant Therapy | Exception Trastuzumab Adjuvant therapy | Exception Lapatinib Adjuvant therapy

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1514463
UMLS CUI [1,2]
C0678222
UMLS CUI [2]
C2267079
UMLS CUI [3,1]
C1705847
UMLS CUI [3,2]
C0728747
UMLS CUI [3,3]
C0600558
UMLS CUI [4,1]
C1705847
UMLS CUI [4,2]
C1506770
UMLS CUI [4,3]
C0600558
UMLS CUI [5,1]
C1705847
UMLS CUI [5,2]
C0728747
UMLS CUI [5,3]
C0677850
UMLS CUI [6,1]
C1705847
UMLS CUI [6,2]
C1506770
UMLS CUI [6,3]
C0677850
disease progression while receiving adjuvant trastuzumab and/or lapatinib treatment
Descrizione

Disease Progression During Adjuvant therapy | trastuzumab | lapatinib

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0242656
UMLS CUI [1,2]
C0347984
UMLS CUI [1,3]
C0677850
UMLS CUI [2]
C0728747
UMLS CUI [3]
C1506770
disease-free interval from completion of adjuvant/neo-adjuvant systemic non-hormonal treatment to recurrence of within 6 months
Descrizione

Interval Disease Free | Completion Systemic therapy Adjuvant | Exception Hormone Therapy | Completion Neoadjuvant Systemic therapy | Disease recurrence

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1272706
UMLS CUI [1,2]
C0012634
UMLS CUI [1,3]
C0332296
UMLS CUI [2,1]
C0205197
UMLS CUI [2,2]
C1515119
UMLS CUI [2,3]
C1522673
UMLS CUI [3,1]
C1705847
UMLS CUI [3,2]
C0279025
UMLS CUI [4,1]
C0205197
UMLS CUI [4,2]
C0600558
UMLS CUI [4,3]
C1515119
UMLS CUI [5]
C0679254
other malignancies in </= 5 years, except for carcinoma in situ of the cervix or basal cell carcinoma
Descrizione

Cancer Other

Tipo di dati

boolean

Alias
UMLS CUI [1]
C1707251
clinical or radiographic evidence of central nervous system (cns) metastases or significant cv disease
Descrizione

CNS metastases | Cardiovascular Disease

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0686377
UMLS CUI [2]
C0007222
Ritorna all'inizio della pagina

Similar models

Eligibility Breast Cancer NCT01491737

1 moduli
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
C1512693 (UMLS CUI)
Gender | Adult | Age
Item
female adult patients, >/=18 years of age
boolean
C0079399 (UMLS CUI [1])
C0001675 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Secondary malignant neoplasm of female breast Advanced HER2 Positive | Secondary malignant neoplasm of female breast Advanced Hormone Receptor Positive | Locally advanced breast cancer HER2 Positive | Locally advanced breast cancer Hormone Receptor Positive
Item
patients with her2-positive and hormone receptor-positive advanced metastatic or locally advanced breast cancer
boolean
C0346993 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C2348909 (UMLS CUI [1,3])
C0346993 (UMLS CUI [2,1])
C0205179 (UMLS CUI [2,2])
C0019929 (UMLS CUI [2,3])
C1514241 (UMLS CUI [2,4])
C3495949 (UMLS CUI [3,1])
C2348909 (UMLS CUI [3,2])
C3495949 (UMLS CUI [4,1])
C0019929 (UMLS CUI [4,2])
C1514241 (UMLS CUI [4,3])
Postmenopausal state
Item
post-menopausal status over 1 year
boolean
C0232970 (UMLS CUI [1])
Primary tumor HER2 Positive | Neoplasm Metastasis HER2 Positive
Item
her2-positive as assessed by local laboratory on primary or metastatic tumor
boolean
C0677930 (UMLS CUI [1,1])
C2348909 (UMLS CUI [1,2])
C0027627 (UMLS CUI [2,1])
C2348909 (UMLS CUI [2,2])
Hormone Receptor Positive Definition | Estrogen receptor positive | Progesterone receptor positive
Item
hormone-receptor positive defined as er-positive and/or pgr-positive
boolean
C0019929 (UMLS CUI [1,1])
C1514241 (UMLS CUI [1,2])
C1704788 (UMLS CUI [1,3])
C0279754 (UMLS CUI [2])
C0279759 (UMLS CUI [3])
Measurable lesion Quantity | Non-Measurable Lesion Quantity
Item
at least one measurable lesion and/or non-measurable disease according to response evaluation criteria in solid tumors (recist)
boolean
C1513041 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C1334988 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
Item Group
C0680251 (UMLS CUI)
Prior Therapy Breast Carcinoma | HER2 Receptor Antagonist | Exception Trastuzumab Neoadjuvant Therapy | Exception Lapatinib Neoadjuvant Therapy | Exception Trastuzumab Adjuvant therapy | Exception Lapatinib Adjuvant therapy
Item
previous treatment with anti-her2 agents for breast cancer, except trastuzumab and/or lapatinib in the neoadjuvant or adjuvant setting
boolean
C1514463 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
C2267079 (UMLS CUI [2])
C1705847 (UMLS CUI [3,1])
C0728747 (UMLS CUI [3,2])
C0600558 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C1506770 (UMLS CUI [4,2])
C0600558 (UMLS CUI [4,3])
C1705847 (UMLS CUI [5,1])
C0728747 (UMLS CUI [5,2])
C0677850 (UMLS CUI [5,3])
C1705847 (UMLS CUI [6,1])
C1506770 (UMLS CUI [6,2])
C0677850 (UMLS CUI [6,3])
Disease Progression During Adjuvant therapy | trastuzumab | lapatinib
Item
disease progression while receiving adjuvant trastuzumab and/or lapatinib treatment
boolean
C0242656 (UMLS CUI [1,1])
C0347984 (UMLS CUI [1,2])
C0677850 (UMLS CUI [1,3])
C0728747 (UMLS CUI [2])
C1506770 (UMLS CUI [3])
Interval Disease Free | Completion Systemic therapy Adjuvant | Exception Hormone Therapy | Completion Neoadjuvant Systemic therapy | Disease recurrence
Item
disease-free interval from completion of adjuvant/neo-adjuvant systemic non-hormonal treatment to recurrence of within 6 months
boolean
C1272706 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
C0332296 (UMLS CUI [1,3])
C0205197 (UMLS CUI [2,1])
C1515119 (UMLS CUI [2,2])
C1522673 (UMLS CUI [2,3])
C1705847 (UMLS CUI [3,1])
C0279025 (UMLS CUI [3,2])
C0205197 (UMLS CUI [4,1])
C0600558 (UMLS CUI [4,2])
C1515119 (UMLS CUI [4,3])
C0679254 (UMLS CUI [5])
Cancer Other
Item
other malignancies in </= 5 years, except for carcinoma in situ of the cervix or basal cell carcinoma
boolean
C1707251 (UMLS CUI [1])
CNS metastases | Cardiovascular Disease
Item
clinical or radiographic evidence of central nervous system (cns) metastases or significant cv disease
boolean
C0686377 (UMLS CUI [1])
C0007222 (UMLS CUI [2])
Ritorna all'inizio della pagina 

Contatto

Si prega di utilizzare questo modulo per feedback, domande e suggerimenti per miglioramenti.

I campi contrassegnati da * sono obbligatori.

Aiuto

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial