ID
36944
Beschrijving
Search for Predictors of Therapeutic Response in Ovarian Carcinoma; ODM derived from: https://clinicaltrials.gov/show/NCT01391351 In order to search for predictors of response to chemotherapy in patients with ovarian carcinoma of the ovary, the fallopian tube or peritoneal serous-type advanced stage, we will define the comparative profiles of miRNA expression of serum polymorphisms and determine differential in 2 patient populations (with or without recurrence 6 months after completion of chemotherapy) with (i) the miRNA profile of serum before treatment and (ii) identification of polymorphisms or SNP (Single Nucleotide Polymorphism) in particular genes involved in the metabolism of chemotherapy agents In the case of miRNA, expression profiles will also be studied during the first course in response to chemotherapy. Indeed, the miRNA profile of serum may be different at baseline among the 2 types of populations (or non-recurrence at 6 months).
Link
https://clinicaltrials.gov/show/NCT01391351
Trefwoorden
Versies (1)
- 23-06-19 23-06-19 -
Houder van rechten
Centre Francois Baclesse
Geüploaded op
23 juni 2019
DOI
Voor een aanvraag inloggen.
Licentie
Creative Commons BY-NC 3.0
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Predictors of Therapeutic Response in Ovarian Carcinoma NCT01391351
Eligibility Criteria
- StudyEvent: Eligibility
Beschrijving
Exclusion Criteria
Alias
- UMLS CUI
- C0680251
Beschrijving
Other hormone or chemotherapy
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0006826
- UMLS CUI [1,2]
- C0205394
- UMLS CUI [1,3]
- C3665472
- UMLS CUI [2,1]
- C0006826
- UMLS CUI [2,2]
- C0205394
- UMLS CUI [2,3]
- C0279025
Beschrijving
Taxol Carboplatin associated chemotherapy
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C3665472
- UMLS CUI [1,2]
- C0332281
- UMLS CUI [1,3]
- C0678133
- UMLS CUI [2,1]
- C3665472
- UMLS CUI [2,2]
- C0332281
- UMLS CUI [2,3]
- C0079083
- UMLS CUI [3,1]
- C3665472
- UMLS CUI [3,2]
- C0332281
- UMLS CUI [3,3]
- C1135130
Beschrijving
Guardianship
Datatype
boolean
Alias
- UMLS CUI [1]
- C0870627
Beschrijving
Prior pelvic radiotherapy
Datatype
boolean
Alias
- UMLS CUI [1,1]
- C0262926
- UMLS CUI [1,2]
- C0030797
- UMLS CUI [1,3]
- C1522449
Beschrijving
History of hematologic malignancy
Datatype
boolean
Alias
- UMLS CUI [1]
- C3696964
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Eligibility Criteria
- StudyEvent: Eligibility
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