ID

36781

Description

Cholinergic Nicotinic Receptors and Cognition in PD; ODM derived from: https://clinicaltrials.gov/show/NCT02076295

Link

https://clinicaltrials.gov/show/NCT02076295

Keywords

Versions (1)
  1. 6/7/19 6/7/19 -
Copyright Holder

See clinicaltrials.gov

Uploaded on

June 7, 2019

DOI

To request one please log in.

License

Creative Commons BY 4.0
Model comments :

You can comment on the data model here. Via the speech bubbles at the itemgroups and items you can add comments to those specificially.

Back to model comments
Itemgroup comments for :

Item comments for :

In order to download data models you must be logged in. Please log in or register for free.

Eligibility Parkinson's Disease NCT02076295

English

Eligibility Parkinson's Disease NCT02076295

1 forms  
Inclusion Criteria
Description

Inclusion Criteria

Alias
UMLS CUI
C1512693
pd subjects (m/f, non-smoking, ≥ 50 years old, hoehn & yahr stages 1-4)
Description

Parkinson Disease Hoehn and Yahr Stage | Non-smoker | Age

Data type

boolean

Alias
UMLS CUI [1,1]
C0030567
UMLS CUI [1,2]
C3639483
UMLS CUI [2]
C0337672
UMLS CUI [3]
C0001779
normal control subjects (n=15, m/f, non-smoking, ≥ 50 years old)
Description

Control Group | Non-smoker | Age

Data type

boolean

Alias
UMLS CUI [1]
C0009932
UMLS CUI [2]
C0337672
UMLS CUI [3]
C0001779
Exclusion Criteria
Description

Exclusion Criteria

Alias
UMLS CUI
C0680251
active smoking, use of other tobacco products, or use of nicotinic drugs such as nicotine patches or varenicline.
Description

Tobacco use | Tobacco product Other | Nicotinic Agents | Nicotine Patch | varenicline

Data type

boolean

Alias
UMLS CUI [1]
C0543414
UMLS CUI [2,1]
C0040329
UMLS CUI [2,2]
C0205394
UMLS CUI [3]
C0028050
UMLS CUI [4]
C0358855
UMLS CUI [5]
C1569608
subjects with contra-indications to mr imaging, including pacemakers or claustrophobia.
Description

Medical contraindication MRI | Artificial cardiac pacemaker | Claustrophobia

Data type

boolean

Alias
UMLS CUI [1,1]
C1301624
UMLS CUI [1,2]
C0024485
UMLS CUI [2]
C0030163
UMLS CUI [3]
C0008909
evidence of large vessel stroke or mass lesion on mri.
Description

Large vessel Cerebrovascular accident | Mass lesion MRI

Data type

boolean

Alias
UMLS CUI [1,1]
C0225990
UMLS CUI [1,2]
C0038454
UMLS CUI [2,1]
C0746408
UMLS CUI [2,2]
C0024485
use of (anti-)cholinergic or neuroleptic drugs.
Description

Anticholinergic Agents | Cholinergic Agents | Antipsychotic Agents

Data type

boolean

Alias
UMLS CUI [1]
C0242896
UMLS CUI [2]
C0242893
UMLS CUI [3]
C0040615
dementia or severe cognitive impairment confirmed by clinical and detailed neuropsychological assessment precluding safe study participation, performing study procedures, or unable to follow directions by study personnel.
Description

Dementia | Severe cognitive impairment | Study Subject Participation Status Excluded | Protocol Compliance Unable

Data type

boolean

Alias
UMLS CUI [1]
C0497327
UMLS CUI [2]
C3554639
UMLS CUI [3,1]
C2348568
UMLS CUI [3,2]
C0332196
UMLS CUI [4,1]
C0525058
UMLS CUI [4,2]
C1299582
evidence of atypical parkinsonism on neurological exam.
Description

Atypical Parkinsonism Neurologic Examination

Data type

boolean

Alias
UMLS CUI [1,1]
C4302185
UMLS CUI [1,2]
C0027853
subjects limited by participation in research procedures involving ionizing radiation.
Description

Study Subject Limited | Study Subject Participation Status | Interventional procedures Involving Ionizing radiation

Data type

boolean

Alias
UMLS CUI [1,1]
C0681850
UMLS CUI [1,2]
C0439801
UMLS CUI [2]
C2348568
UMLS CUI [3,1]
C0184661
UMLS CUI [3,2]
C1314939
UMLS CUI [3,3]
C0034538
pregnancy (test within 48 hours of each pet session) or breastfeeding
Description

Pregnancy | Breast Feeding

Data type

boolean

Alias
UMLS CUI [1]
C0032961
UMLS CUI [2]
C0006147
Back to the top of the page

Similar models

Eligibility Parkinson's Disease NCT02076295

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
C1512693 (UMLS CUI)
Parkinson Disease Hoehn and Yahr Stage | Non-smoker | Age
Item
pd subjects (m/f, non-smoking, ≥ 50 years old, hoehn & yahr stages 1-4)
boolean
C0030567 (UMLS CUI [1,1])
C3639483 (UMLS CUI [1,2])
C0337672 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Control Group | Non-smoker | Age
Item
normal control subjects (n=15, m/f, non-smoking, ≥ 50 years old)
boolean
C0009932 (UMLS CUI [1])
C0337672 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
Item Group
C0680251 (UMLS CUI)
Tobacco use | Tobacco product Other | Nicotinic Agents | Nicotine Patch | varenicline
Item
active smoking, use of other tobacco products, or use of nicotinic drugs such as nicotine patches or varenicline.
boolean
C0543414 (UMLS CUI [1])
C0040329 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
C0028050 (UMLS CUI [3])
C0358855 (UMLS CUI [4])
C1569608 (UMLS CUI [5])
Medical contraindication MRI | Artificial cardiac pacemaker | Claustrophobia
Item
subjects with contra-indications to mr imaging, including pacemakers or claustrophobia.
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0030163 (UMLS CUI [2])
C0008909 (UMLS CUI [3])
Large vessel Cerebrovascular accident | Mass lesion MRI
Item
evidence of large vessel stroke or mass lesion on mri.
boolean
C0225990 (UMLS CUI [1,1])
C0038454 (UMLS CUI [1,2])
C0746408 (UMLS CUI [2,1])
C0024485 (UMLS CUI [2,2])
Anticholinergic Agents | Cholinergic Agents | Antipsychotic Agents
Item
use of (anti-)cholinergic or neuroleptic drugs.
boolean
C0242896 (UMLS CUI [1])
C0242893 (UMLS CUI [2])
C0040615 (UMLS CUI [3])
Dementia | Severe cognitive impairment | Study Subject Participation Status Excluded | Protocol Compliance Unable
Item
dementia or severe cognitive impairment confirmed by clinical and detailed neuropsychological assessment precluding safe study participation, performing study procedures, or unable to follow directions by study personnel.
boolean
C0497327 (UMLS CUI [1])
C3554639 (UMLS CUI [2])
C2348568 (UMLS CUI [3,1])
C0332196 (UMLS CUI [3,2])
C0525058 (UMLS CUI [4,1])
C1299582 (UMLS CUI [4,2])
Atypical Parkinsonism Neurologic Examination
Item
evidence of atypical parkinsonism on neurological exam.
boolean
C4302185 (UMLS CUI [1,1])
C0027853 (UMLS CUI [1,2])
Study Subject Limited | Study Subject Participation Status | Interventional procedures Involving Ionizing radiation
Item
subjects limited by participation in research procedures involving ionizing radiation.
boolean
C0681850 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2])
C0184661 (UMLS CUI [3,1])
C1314939 (UMLS CUI [3,2])
C0034538 (UMLS CUI [3,3])
Pregnancy | Breast Feeding
Item
pregnancy (test within 48 hours of each pet session) or breastfeeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Back to the top of the page 

Contact

Please use this form for feedback, questions and suggestions for improvements.

Fields marked with * are required.

Help

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial