ID

33344

Description

Study ID: 100601 Clinical Study ID: LPL100601 Study Title: LPL100601, A Clinical Outcomes Study of Darapladib versus Placebo in Subjects with Chronic Coronary Heart Disease to Compare the Incidence of Major Adverse Cardiovascular Events (MACE) Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00799903 Sponsor: GlaxoSmithKline Collaborators: N/A Phase: phase 3 Study Recruitment Status: Completed Generic Name: darapladib Trade Name: darapladib Study Indication: Atherosclerosis Study part: Liver biopsy - Repeating form (Unscheduled/Dynamic visit)

Keywords

  1. 10/11/17 10/11/17 -
  2. 10/16/17 10/16/17 -
  3. 10/23/17 10/23/17 -
  4. 1/2/18 1/2/18 -
  5. 1/2/18 1/2/18 -
  6. 12/6/18 12/6/18 - Sarah Riepenhausen
Copyright Holder

GlaxoSmithKline

Uploaded on

December 6, 2018

DOI

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License

Creative Commons BY-NC 3.0

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Liver biopsy GSK study Chronic Coronary Heart Disease NCT00799903

Liver biopsy GSK study Chronic Coronary Heart Disease NCT00799903

Date of liver biopsy
Description

Date of liver biopsy

Alias
UMLS CUI-1
C0193388
UMLS CUI-2
C0011008
1. Date of liver biopsy
Description

Date of liver biopsy

Data type

date

Alias
UMLS CUI [1,1]
C0193388
UMLS CUI [1,2]
C0011008
Biopsy size
Description

Biopsy size

Alias
UMLS CUI-1
C1299482
UMLS CUI-2
C0193388
2. Approximate size of liver biopsy
Description

Liver Biopsy size

Data type

integer

Measurement units
  • mm
Alias
UMLS CUI [1,1]
C1299482
UMLS CUI [1,2]
C0193388
mm
3. Biopsy size unit
Description

[hidden]

Data type

text

Alias
UMLS CUI [1,1]
C1299482
UMLS CUI [1,2]
C0193388
UMLS CUI [1,3]
C1519795
Final Diagnosis
Description

Final Diagnosis

Alias
UMLS CUI-1
C1546485
UMLS CUI-2
C0193388
4. Final Diagnosis
Description

Final Diagnosis

Data type

text

Alias
UMLS CUI [1,1]
C1546485
UMLS CUI [1,2]
C0193388
[A1] Acute hepatitis
Description

Acute hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0267797
[A2] Chronic hepatitis
Description

Chronic hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0019189
[A3] Cholestatic hepatitis
Description

Cholestatic hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0149904
[A4] Drug-induced cholestasis
Description

Drug-induced cholestasis

Data type

boolean

Alias
UMLS CUI [1]
C2062350
[A5] Acute viral hepatitis
Description

Acute viral hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0276622
[A6] Chronic viral hepatitis
Description

Chronic viral hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0276623
[A7] Drug-induced hepatitis
Description

Drug-induced hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C1262760
[A8] Autoimmune hepatitis
Description

Autoimmune hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0241910
[A9] Bridging necrosis
Description

Liver Bridging necrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C0333511
UMLS CUI [1,2]
C0023884
[A10] Submassive hepatic necrosis
Description

Submassive hepatic necrosis

Data type

boolean

Alias
UMLS CUI [1]
C0151798
[A11] Massive hepatic necrosis
Description

Massive hepatic necrosis

Data type

boolean

Alias
UMLS CUI [1]
C0001364
[A12] Steatosis - microvesicular
Description

Steatosis - microvesicular

Data type

boolean

Alias
UMLS CUI [1]
C1850415
[A13] Steatosis - macrovesicular
Description

Steatosis - macrovesicular

Data type

boolean

Alias
UMLS CUI [1]
C1837256
[A14] Steatosis - mixed
Description

Steatosis - mixed

Data type

boolean

Alias
UMLS CUI [1,1]
C0015695
UMLS CUI [1,2]
C0205430
[A15] Non-alcoholic steatohepatitis
Description

Non-alcoholic steatohepatitis

Data type

boolean

Alias
UMLS CUI [1]
C3241937
[A16] Alcoholic hepatitis
Description

Alcoholic hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0019187
[A17] Hepatic granulomas
Description

Hepatic granulomas

Data type

boolean

Alias
UMLS CUI [1]
C0745754
[A18] Sarcoidosis
Description

Liver Sarcoidosis

Data type

boolean

Alias
UMLS CUI [1]
C0744822
[A19] Fibrosis
Description

Liver Fibrosis

Data type

boolean

Alias
UMLS CUI [1]
C0239946
[A20] Cirrhosis
Description

Cirrhosis

Data type

boolean

Alias
UMLS CUI [1]
C0023890
[A21] Primary biliary cirrhosis
Description

Primary biliary cirrhosis

Data type

boolean

Alias
UMLS CUI [1]
C0008312
[A22] Primary sclerosing cholangitis
Description

Primary sclerosing cholangitis

Data type

boolean

Alias
UMLS CUI [1]
C0008311
[A23] Autoimmune overlap syndrome
Description

Autoimmune overlap syndrome

Data type

boolean

Alias
UMLS CUI [1]
C2702837
[A24] Hemochromatosis
Description

Hemochromatosis

Data type

boolean

Alias
UMLS CUI [1]
C0018995
[A25] Alpha-1-antitrypsin deficiency
Description

Alpha-1-antitrypsin deficiency

Data type

boolean

Alias
UMLS CUI [1]
C0221757
[A26] Wilson's disease
Description

Wilson's disease

Data type

boolean

Alias
UMLS CUI [1]
C0019202
[A27] Veno-occlusive disease
Description

Liver: Veno-occlusive disease

Data type

boolean

Alias
UMLS CUI [1]
C0019156
[A28] Budd-Chiari syndrome
Description

Budd-Chiari syndrome

Data type

boolean

Alias
UMLS CUI [1]
C0856761
[A29] Neoplasia
Description

Liver Neoplasia

Data type

boolean

Alias
UMLS CUI [1,1]
C1882062
UMLS CUI [1,2]
C0023884
[A99] Other
Description

Other Final Diagnosis

Data type

boolean

Alias
UMLS CUI [1,1]
C1546485
UMLS CUI [1,2]
C0205394
Other, specify:
Description

Other Final Diagnosis specification

Data type

text

Alias
UMLS CUI [1,1]
C1546485
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235
Liver Architecture
Description

Liver Architecture

Alias
UMLS CUI-1
C0023884
UMLS CUI-2
C0935919
5. Liver Architecture
Description

Liver Architecture

Data type

text

Alias
UMLS CUI [1,1]
C0935919
UMLS CUI [1,2]
C0023884
[B2] Bridging fibrosis
Description

Liver: Bridging fibrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C0334160
UMLS CUI [1,2]
C0023884
[B3] Diffuse fibrosis
Description

Diffuse fibrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C1265984
UMLS CUI [1,2]
C0023884
[B4] Nodular regenerative hyperplasia
Description

Liver: Nodular regenerative hyperplasia

Data type

boolean

Alias
UMLS CUI [1,1]
C0020510
UMLS CUI [1,2]
C0023884
[B5] Congenital hepatic fibrosis
Description

Congenital hepatic fibrosis

Data type

boolean

Alias
UMLS CUI [1]
C0009714
[B6] Cirrhosis
Description

Cirrhosis

Data type

boolean

Alias
UMLS CUI [1]
C0023890
[B7] Centrilobular congestion
Description

Centrilobular congestion

Data type

boolean

Alias
UMLS CUI [1,1]
C0267821
UMLS CUI [1,2]
C0442080
[B8] Endophlebitis
Description

Liver Endophlebitis

Data type

boolean

Alias
UMLS CUI [1,1]
C0014234
UMLS CUI [1,2]
C0023884
[B9] Veno-occlusive disease
Description

Liver Veno-occlusive disease

Data type

boolean

Alias
UMLS CUI [1]
C0019156
[B10] Canalicular cholestasis
Description

Canalicular cholestasis

Data type

boolean

Alias
UMLS CUI [1]
C3150342
[B11] Apoptosis
Description

Liver Apoptosis

Data type

boolean

Alias
UMLS CUI [1,1]
C0162638
UMLS CUI [1,2]
C0023884
[B12] Focal (or spotty or mild) hepatocellular necrosis
Description

Focal (or spotty or mild) hepatocellular necrosis

Data type

boolean

Alias
UMLS CUI [1]
C0267800
[B13] Interface hepatitis (periportal hepatitis or piecemeal necrosis)
Description

Interface hepatitis

Data type

boolean

Alias
UMLS CUI [1,1]
C0333515
UMLS CUI [1,2]
C0023884
[B14] Ischaemic necrosis
Description

Liver: Ischaemic necrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C3887513
UMLS CUI [1,2]
C0023884
[B15] Centrolobular (Zone 3) necrosis
Description

Centrolobular necrosis

Data type

boolean

Alias
UMLS CUI [1]
C3672032
[B16] Focal coagulative necrosis
Description

Focal coagulative necrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C1522058
UMLS CUI [1,2]
C0205234
[B17] Centrolobular (Zone 3) coagulative necrosis
Description

Centrolobular coagulative necrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C1522058
UMLS CUI [1,2]
C0682619
[B18] Bridging hepatocellular necrosis
Description

Bridging hepatocellular necrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C1855038
UMLS CUI [1,2]
C0333511
[B19] Massive or panlobular hepatocellular necrosis
Description

Massive or panlobular hepatocellular necrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C1855038
UMLS CUI [1,2]
C0442131
UMLS CUI [2]
C0001364
[B20] Dysplasia
Description

Liver Dysplasia

Data type

boolean

Alias
UMLS CUI [1,1]
C0334044
UMLS CUI [1,2]
C0023884
[B21] Neoplasia
Description

Liver Neoplasia

Data type

boolean

Alias
UMLS CUI [1,1]
C1882062
UMLS CUI [1,2]
C0023884
[B99] Other
Description

Other Liver Architecture

Data type

boolean

Alias
UMLS CUI [1,1]
C0023884
UMLS CUI [1,2]
C0935919
UMLS CUI [1,3]
C0205394
Other, specify:
Description

Other Liver Architecture specification

Data type

text

Alias
UMLS CUI [1,1]
C0935919
UMLS CUI [1,2]
C0023884
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C2348235
Description of Liver Cells or Hepatocytes
Description

Description of Liver Cells or Hepatocytes

Alias
UMLS CUI-1
C0227525
UMLS CUI-2
C0678257
6. Description of Liver Cells or Hepatocytes
Description

Description of or Hepatocytes

Data type

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0678257
[C1] Ballooning
Description

Ballooning Liver Cells or Hepatocytes

Data type

boolean

Alias
UMLS CUI [1,1]
C0333445
UMLS CUI [1,2]
C0227525
[C2] Acidophilic
Description

Acidophilic Liver Cells or Hepatocytes

Data type

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0333931
[C3] Pseudoxanthomatous
Description

Pseudoxanthomatous Liver Cells or Hepatocytes

Data type

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C3277905
[C4] Multinucleated giant hepatocytes
Description

Multinucleated giant hepatocytes

Data type

boolean

Alias
UMLS CUI [1,1]
C3550474
UMLS CUI [1,2]
C1850414
[C99] Other
Description

Other Liver Cells or Hepatocytes

Data type

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0678257
UMLS CUI [1,3]
C0205394
Other, specify:
Description

Other Liver Cells or Hepatocytes specification

Data type

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0678257
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C2348235
Liver Cell or Hepatocyte Inclusions or Vacuoles
Description

Liver Cell or Hepatocyte Inclusions or Vacuoles

Alias
UMLS CUI-1
C0227525
UMLS CUI-2
C1512693
UMLS CUI-3
C0042219
7. Liver Cell or Hepatocyte Inclusions or Vacuoles
Description

Liver Cell or Hepatocyte Inclusions or Vacuoles

Data type

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0042219
UMLS CUI [2,1]
C0227525
UMLS CUI [2,2]
C1512693
[D1] Macrovesicular steatosis
Description

Macrovesicular steatosis

Data type

boolean

Alias
UMLS CUI [1]
C1837256
D2] Microvesicular steatosis
Description

Microvesicular steatosis

Data type

boolean

Alias
UMLS CUI [1]
C1850415
[D3] Bile accumulation
Description

Bile accumulation

Data type

boolean

Alias
UMLS CUI [1]
C3686784
[D4] Diastase-resistant, PAS-positive cytoplasmic inclusions
Description

Diastase-resistant, PAS-positive cytoplasmic inclusions

Data type

boolean

Alias
UMLS CUI [1]
C1856311
[D5] Alpha-1-antitrypsin inclusions
Description

Alpha-1-antitrypsin inclusions

Data type

boolean

Alias
UMLS CUI [1,1]
C0002191
UMLS CUI [1,2]
C1512693
UMLS CUI [1,3]
C0227525
[D6] Megamitochondria
Description

Megamitochondria

Data type

boolean

Alias
UMLS CUI [1,1]
C0544931
UMLS CUI [1,2]
C0227525
[D7] Mallory bodies
Description

Mallory bodies

Data type

boolean

Alias
UMLS CUI [1]
C0333744
[D8] "Ground Glass" inclusions
Description

Ground Glass inclusions

Data type

boolean

Alias
UMLS CUI [1]
C0598786
[D9] Lipofuscin pigment
Description

Hepatocyte Lipofuscin pigment

Data type

boolean

Alias
UMLS CUI [1,1]
C0023789
UMLS CUI [1,2]
C0227525
[D10] Hemosiderin granules
Description

Hemosiderin granules

Data type

boolean

Alias
UMLS CUI [1,1]
C0019113
UMLS CUI [1,2]
C0227525
[D11] Orcein-positive cytoplasmin granules
Description

Orcein-positive cytoplasmin granules

Data type

boolean

Alias
UMLS CUI [1,1]
C0069596
UMLS CUI [1,2]
C0227525
[D12] Protoporphyrin crystals (birefringent under polarised light)
Description

Protoporphyrin crystals

Data type

boolean

Alias
UMLS CUI [1,1]
C0033733
UMLS CUI [1,2]
C0227525
[D13] Uroporphyrin crystals (red fluorescence under ultraviolet light)
Description

Uroporphyrin crystals

Data type

boolean

Alias
UMLS CUI [1,1]
C0042093
UMLS CUI [1,2]
C0227525
[D99] Other
Description

Other Liver Cell or Hepatocyte Inclusions or Vacuoles

Data type

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0042219
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C0227525
UMLS CUI [2,2]
C1512693
UMLS CUI [2,3]
C0205394
Other, specify:
Description

Other Liver Cell or Hepatocyte Inclusions or Vacuoles specification

Data type

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0042219
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C0227525
UMLS CUI [2,2]
C1512693
UMLS CUI [2,3]
C0205394
UMLS CUI [3]
C1521902
Hepatocyte or Liver Cell Nuclear Abnormalities
Description

Hepatocyte or Liver Cell Nuclear Abnormalities

Alias
UMLS CUI-1
C0227525
UMLS CUI-2
C1849376
8. Hepatocyte or Liver Cell Nuclear Abnormalities
Description

Hepatocyte or Liver Cell Nuclear Abnormalities

Data type

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C1849376
[E1] Hepatocellular mitosis
Description

Hepatocellular mitosis

Data type

boolean

Alias
UMLS CUI [1,1]
C2697585
UMLS CUI [1,2]
C0026255
[E2] Binucleated or multinucleated hepatocytes
Description

Binucleated or multinucleated hepatocytes

Data type

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C0333909
UMLS CUI [2]
C4054455
[E3] CMV inclusion bodies
Description

CMV inclusion bodies

Data type

boolean

Alias
UMLS CUI [1,1]
C0582172
UMLS CUI [1,2]
C1366904
UMLS CUI [1,3]
C0227525
[E4] HSV inclusions
Description

HSV inclusions

Data type

boolean

Alias
UMLS CUI [1,1]
C0319232
UMLS CUI [1,2]
C1366904
UMLS CUI [1,3]
C0227525
[E5] Varicella inclusions
Description

Varicella inclusions

Data type

boolean

Alias
UMLS CUI [1,1]
C0740380
UMLS CUI [1,2]
C1366904
UMLS CUI [1,3]
C0227525
[E99] Other
Description

Other Hepatocyte or Liver Cell Nuclear Abnormalities

Data type

boolean

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C1849376
UMLS CUI [1,3]
C0205394
Other, specify:
Description

Other Hepatocyte or Liver Cell Nuclear Abnormalities specification

Data type

text

Alias
UMLS CUI [1,1]
C0227525
UMLS CUI [1,2]
C1849376
UMLS CUI [1,3]
C0205394
UMLS CUI [1,4]
C1521902
Liver or Lobular Infiltrates
Description

Liver or Lobular Infiltrates

Alias
UMLS CUI-1
C0205417
UMLS CUI-2
C1400896
UMLS CUI-4
C1400896
9. Liver or Lobular Infiltrates
Description

Liver or Lobular Infiltrates

Data type

text

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [2]
C1400896
[F1] Eosinophils
Description

Liver or Lobular Infiltrates Eosinophils

Data type

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0014467
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0014467
[F2] Lymphocytes
Description

Liver or Lobular Infiltrates Lymphocytes

Data type

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0024264
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0024264
[F3] Plasma cells
Description

Liver or Lobular Infiltrates Plasma cells

Data type

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0032112
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0032112
[F4] Neutrophils
Description

Liver or Lobular Infiltrates Neutrophils

Data type

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0027950
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0027950
[F5] Macrophages and proliferating Kupffer cells
Description

Liver or Lobular Infiltrates Macrophages and proliferating Kupffer cells

Data type

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0022801
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0022801
UMLS CUI [3]
C1168262
[F6] Granulomas
Description

Liver or Lobular Infiltrates Granulomas

Data type

boolean

Alias
UMLS CUI [1,1]
C0745754
UMLS CUI [1,2]
C0205417
UMLS CUI [2]
C0745754
[F99] Other
Description

Other Liver or Lobular Infiltrates

Data type

boolean

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0205394
Other, specify:
Description

Other Liver or Lobular Infiltrates specification

Data type

text

Alias
UMLS CUI [1,1]
C0205417
UMLS CUI [1,2]
C1400896
UMLS CUI [1,3]
C0205394
UMLS CUI [2,1]
C1400896
UMLS CUI [2,2]
C0205394
UMLS CUI [3]
C1521902
Portal Tract Inflammation
Description

Portal Tract Inflammation

Alias
UMLS CUI-1
C3854488
10. Portal Tract Inflammation
Description

Portal Tract Inflammation

Data type

text

Alias
UMLS CUI [1]
C3854488
[G1] Eosinophils
Description

Portal Tract Inflammation Eosinophils

Data type

boolean

Alias
UMLS CUI [1,1]
C0014467
UMLS CUI [1,2]
C3854488
[G2] Lymphoid aggregates and/or follicles
Description

Portal Tract Inflammation Lymphoid aggregates and/or follicles

Data type

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0229653
[G3] Plasma cells
Description

Portal Tract Inflammation Plasma cells

Data type

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0032112
[G4] Neutrophils
Description

Portal Tract Inflammation Neutrophils

Data type

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0027950
[G5] Histocytes and macrophages
Description

Portal Tract Inflammation Histocytes and macrophages

Data type

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0024432
UMLS CUI [2,1]
C3854488
UMLS CUI [2,2]
C0019612
[G99] Other
Description

Other Portal Tract Inflammation

Data type

boolean

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C0205394
Other, specify:
Description

Other Portal Tract Inflammation specification

Data type

text

Alias
UMLS CUI [1,1]
C3854488
UMLS CUI [1,2]
C3845569
Bile Ducts
Description

Bile Ducts

Alias
UMLS CUI-1
C0005400
11. Bile Ducts
Description

Bile Ducts

Data type

text

Alias
UMLS CUI [1]
C0005400
[H1] Proliferation of bile ducts (bile ductular reaction)
Description

Proliferation of bile ducts

Data type

boolean

Alias
UMLS CUI [1,1]
C0005400
UMLS CUI [1,2]
C0334094
[H2] Dilation, degeneration or disruption of portal bile ducts
Description

Dilation, degeneration or disruption of portal bile ducts

Data type

boolean

Alias
UMLS CUI [1,1]
C0005400
UMLS CUI [1,2]
C0011164
UMLS CUI [2]
C1849767
UMLS CUI [3,1]
C0005400
UMLS CUI [3,2]
C0332453
[H3] Paucity of bile ducts
Description

Paucity of bile ducts

Data type

boolean

Alias
UMLS CUI [1]
C4273160
[H4] Periductal fibrosis
Description

Periductal fibrosis

Data type

boolean

Alias
UMLS CUI [1,1]
C0016059
UMLS CUI [1,2]
C0005400
[H99] Other
Description

Bile ducts Other

Data type

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0005400
Other, specify
Description

Bile ducts Other specification

Data type

text

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0005400
UMLS CUI [1,3]
C2348235
Portal Veins
Description

Portal Veins

Alias
UMLS CUI-1
C0032718
12. Portal Veins
Description

Portal Veins

Data type

text

Alias
UMLS CUI [1]
C0032718
[I1] Pyelophlebitis
Description

Pyelophlebitis

Data type

boolean

Alias
UMLS CUI [1,1]
C1405883
UMLS CUI [1,2]
C0032718
[I2] Thrombosis, sclerosis or occlusion of portal vein
Description

Thrombosis, sclerosis or occlusion of portal vein

Data type

boolean

Alias
UMLS CUI [1]
C0155773
UMLS CUI [2]
C0400960
UMLS CUI [3]
C0265029
[I3] Neoplastic invasion of portal vein
Description

Neoplastic invasion of portal vein

Data type

boolean

Alias
UMLS CUI [1,1]
C1709160
UMLS CUI [1,2]
C1510886
UMLS CUI [1,3]
C0032718
[I4] Granulomatous compression of portal vein
Description

Granulomatous compression of portal vein

Data type

boolean

Alias
UMLS CUI [1,1]
C0032718
UMLS CUI [1,2]
C0439667
UMLS CUI [1,3]
C0728907
[I99] Other
Description

Portal veins Other

Data type

boolean

Alias
UMLS CUI [1,1]
C0032718
UMLS CUI [1,2]
C0205394
Other, specify:
Description

Portal veins Other specification

Data type

text

Alias
UMLS CUI [1,1]
C0032718
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235
Liver Infections
Description

Liver Infections

Alias
UMLS CUI-1
C1112211
13. Liver Infections
Description

Liver Infections

Data type

text

Alias
UMLS CUI [1]
C1112211
[J1] Leishmaniasis donovani
Description

Liver: Leishmaniasis donovani

Data type

boolean

Alias
UMLS CUI [1,1]
C0023273
UMLS CUI [1,2]
C1112211
[J2] Plasmodium falciparum
Description

Liver: Plasmodium falciparum

Data type

boolean

Alias
UMLS CUI [1,1]
C0032150
UMLS CUI [1,2]
C1112211
[J3] Toxoplasmosis
Description

Liver: Toxoplasmosis

Data type

boolean

Alias
UMLS CUI [1,1]
C0040558
UMLS CUI [1,2]
C1112211
[J4] Cryptococcus neoformans
Description

Liver: Cryptococcus neoformans

Data type

boolean

Alias
UMLS CUI [1,1]
C0010416
UMLS CUI [1,2]
C1112211
[J5] Histoplasma capsulatum
Description

Liver: Histoplasma capsulatum

Data type

boolean

Alias
UMLS CUI [1,1]
C0319941
UMLS CUI [1,2]
C1112211
[J6] Mycobacterium tuberculois
Description

Liver: Mycobacterium tuberculois

Data type

boolean

Alias
UMLS CUI [1,1]
C0026926
UMLS CUI [1,2]
C1112211
[J7] Other mycobacterial species
Description

Other mycobacterial species

Data type

boolean

Alias
UMLS CUI [1,1]
C0205394
UMLS CUI [1,2]
C0026918
UMLS CUI [1,3]
C1112211
[J99] Other
Description

Other Liver Infections

Data type

boolean

Alias
UMLS CUI [1,1]
C1112211
UMLS CUI [1,2]
C0205394
Other, specify:
Description

Other Liver Infections specification

Data type

text

Alias
UMLS CUI [1,1]
C1112211
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235
Parasites or Ova
Description

Parasites or Ova

Alias
UMLS CUI-1
C0030498
UMLS CUI-2
C1267673
UMLS CUI-3
C0023884
14. Parasites or Ova
Description

Parasites or Ova

Data type

text

Alias
UMLS CUI [1,1]
C0030498
UMLS CUI [1,2]
C0023884
UMLS CUI [2,1]
C0555117
UMLS CUI [2,2]
C0023884
[K1] Schistosome and/or ova
Description

Schistosome and/or ova

Data type

boolean

Alias
UMLS CUI [1,1]
C4303012
UMLS CUI [1,2]
C0023884
UMLS CUI [2,1]
C0036315
UMLS CUI [2,2]
C0023884
[K2] Ascaris and/or ova
Description

Ascaris and/or ova

Data type

boolean

Alias
UMLS CUI [1,1]
C3698183
UMLS CUI [1,2]
C0023884
UMLS CUI [2,1]
C0003954
UMLS CUI [2,2]
C0023884
[K3] Toxocara and/or ova
Description

Toxocara and/or ova

Data type

boolean

Alias
UMLS CUI [1,1]
C0040550
UMLS CUI [1,2]
C1267673
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C0040550
UMLS CUI [2,2]
C0023884
[K4] Echinococcus cysts
Description

Echinococcus cysts

Data type

boolean

Alias
UMLS CUI [1]
C0013502
[K5] Hepatic capillariasis worms and/or ova
Description

Hepatic capillariasis worms and/or ova

Data type

boolean

Alias
UMLS CUI [1,1]
C0006896
UMLS CUI [1,2]
C1267673
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C0277202
UMLS CUI [2,2]
C0023884
[K99] Other
Description

Other Parasites or Ova

Data type

boolean

Alias
UMLS CUI [1,1]
C0030498
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C1267673
UMLS CUI [2,2]
C0205394
UMLS CUI [2,3]
C0023884
Other, specify:
Description

Other Parasites or Ova specification

Data type

text

Alias
UMLS CUI [1,1]
C0030498
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C0023884
UMLS CUI [2,1]
C1267673
UMLS CUI [2,2]
C0205394
UMLS CUI [2,3]
C0023884
UMLS CUI [3]
C2348235
15. Histologic Staining or Additional Studies Obtained
Description

15. Histologic Staining or Additional Studies Obtained

Alias
UMLS CUI-1
C0487602
UMLS CUI-2
C0430022
UMLS CUI-3
C0023884
[L1] Haematoxylin and eosin (or H & E)
Description

Haematoxylin and eosin

Data type

boolean

Alias
UMLS CUI [1]
C0523207
[L2] Masson
Description

Masson

Data type

boolean

Alias
UMLS CUI [1]
C1294297
[L3] Toluidine blue or Giemsa
Description

Toluidine blue or Giemsa

Data type

boolean

Alias
UMLS CUI [1]
C0523203
UMLS CUI [2]
C0017542
[L4] Prussian blue
Description

Prussian blue

Data type

boolean

Alias
UMLS CUI [1]
C1294004
[L5] Periodic Acidic Schiff (PAS), with or without diastase
Description

Periodic Acidic Schiff with or without diastase

Data type

boolean

Alias
UMLS CUI [1,1]
C0440048
UMLS CUI [1,2]
C0002712
UMLS CUI [2,1]
C0440048
UMLS CUI [2,2]
C0332288
UMLS CUI [2,3]
C0002712
[L6] Oil red O
Description

Oil red O

Data type

boolean

Alias
UMLS CUI [1]
C1294000
[L7] Congo red
Description

Congo red

Data type

boolean

Alias
UMLS CUI [1]
C0009742
[L8] Hall's stain
Description

Hall's stain

Data type

boolean

Alias
UMLS CUI [1]
C1720394
[L9] Gridley's stain
Description

Gridley's stain

Data type

boolean

Alias
UMLS CUI [1]
C1293978
[L10] Rhodanine (copper)
Description

Rhodanine

Data type

boolean

Alias
UMLS CUI [1,1]
C0035486
UMLS CUI [1,2]
C0009968
UMLS CUI [1,3]
C0487602
[L11] Rubeanic acid (copper)
Description

Rubeanic acid

Data type

boolean

Alias
UMLS CUI [1,1]
C0073680
UMLS CUI [1,2]
C0009968
UMLS CUI [1,3]
C0487602
[L12] Orcein, aldehyde fuchsin or Victoria blue
Description

Orcein, aldehyde fuchsin or Victoria blue

Data type

boolean

Alias
UMLS CUI [1]
C1294001
UMLS CUI [2]
C0491984
UMLS CUI [3,1]
C0078232
UMLS CUI [3,2]
C0487602
[L13] Electron microscopy
Description

Electron microscopy

Data type

boolean

Alias
UMLS CUI [1]
C0026019
[L14] Hepatitis A immunostains positive
Description

Hepatitis A immunostains positive

Data type

boolean

Alias
UMLS CUI [1,1]
C0560226
UMLS CUI [1,2]
C3687908
[L15] Hepatitis B core antigen or hepatitis B surface antibody immunostains positive
Description

Hepatitis B core antigen or hepatitis B surface antibody immunostains positive

Data type

boolean

Alias
UMLS CUI [1,1]
C0019166
UMLS CUI [1,2]
C3687908
UMLS CUI [2,1]
C0369334
UMLS CUI [2,2]
C3687908
[L16] Hepatitis D immunostains
Description

Hepatitis D immunostains

Data type

boolean

Alias
UMLS CUI [1,1]
C0011226
UMLS CUI [1,2]
C3687908
[L17] Other immunostains
Description

Other immunostains

Data type

boolean

Alias
UMLS CUI [1,1]
C3687908
UMLS CUI [1,2]
C0205394
[L99] Other
Description

Other Histologic Staining or Additional Studies Obtained

Data type

boolean

Alias
UMLS CUI [1,1]
C0487602
UMLS CUI [1,2]
C0205394
Other, specify:
Description

Other Histologic Staining or Additional Studies Obtained specification

Data type

text

Alias
UMLS CUI [1,1]
C0487602
UMLS CUI [1,2]
C0205394
UMLS CUI [1,3]
C2348235

Similar models

Liver biopsy GSK study Chronic Coronary Heart Disease NCT00799903

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Date of liver biopsy
C0193388 (UMLS CUI-1)
C0011008 (UMLS CUI-2)
Date of liver biopsy
Item
1. Date of liver biopsy
date
C0193388 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item Group
Biopsy size
C1299482 (UMLS CUI-1)
C0193388 (UMLS CUI-2)
Liver Biopsy size
Item
2. Approximate size of liver biopsy
integer
C1299482 (UMLS CUI [1,1])
C0193388 (UMLS CUI [1,2])
Biopsy size unit
Item
3. Biopsy size unit
text
C1299482 (UMLS CUI [1,1])
C0193388 (UMLS CUI [1,2])
C1519795 (UMLS CUI [1,3])
Item Group
Final Diagnosis
C1546485 (UMLS CUI-1)
C0193388 (UMLS CUI-2)
Item
4. Final Diagnosis
text
C1546485 (UMLS CUI [1,1])
C0193388 (UMLS CUI [1,2])
Code List
4. Final Diagnosis
CL Item
Normal (A0)
CL Item
Check all that apply (AAA)
Acute hepatitis
Item
[A1] Acute hepatitis
boolean
C0267797 (UMLS CUI [1])
Chronic hepatitis
Item
[A2] Chronic hepatitis
boolean
C0019189 (UMLS CUI [1])
Cholestatic hepatitis
Item
[A3] Cholestatic hepatitis
boolean
C0149904 (UMLS CUI [1])
Drug-induced cholestasis
Item
[A4] Drug-induced cholestasis
boolean
C2062350 (UMLS CUI [1])
Acute viral hepatitis
Item
[A5] Acute viral hepatitis
boolean
C0276622 (UMLS CUI [1])
Chronic viral hepatitis
Item
[A6] Chronic viral hepatitis
boolean
C0276623 (UMLS CUI [1])
Drug-induced hepatitis
Item
[A7] Drug-induced hepatitis
boolean
C1262760 (UMLS CUI [1])
Autoimmune hepatitis
Item
[A8] Autoimmune hepatitis
boolean
C0241910 (UMLS CUI [1])
Liver Bridging necrosis
Item
[A9] Bridging necrosis
boolean
C0333511 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Submassive hepatic necrosis
Item
[A10] Submassive hepatic necrosis
boolean
C0151798 (UMLS CUI [1])
Massive hepatic necrosis
Item
[A11] Massive hepatic necrosis
boolean
C0001364 (UMLS CUI [1])
Steatosis - microvesicular
Item
[A12] Steatosis - microvesicular
boolean
C1850415 (UMLS CUI [1])
Steatosis - macrovesicular
Item
[A13] Steatosis - macrovesicular
boolean
C1837256 (UMLS CUI [1])
Steatosis - mixed
Item
[A14] Steatosis - mixed
boolean
C0015695 (UMLS CUI [1,1])
C0205430 (UMLS CUI [1,2])
Non-alcoholic steatohepatitis
Item
[A15] Non-alcoholic steatohepatitis
boolean
C3241937 (UMLS CUI [1])
Alcoholic hepatitis
Item
[A16] Alcoholic hepatitis
boolean
C0019187 (UMLS CUI [1])
Hepatic granulomas
Item
[A17] Hepatic granulomas
boolean
C0745754 (UMLS CUI [1])
Liver Sarcoidosis
Item
[A18] Sarcoidosis
boolean
C0744822 (UMLS CUI [1])
Liver Fibrosis
Item
[A19] Fibrosis
boolean
C0239946 (UMLS CUI [1])
Cirrhosis
Item
[A20] Cirrhosis
boolean
C0023890 (UMLS CUI [1])
Primary biliary cirrhosis
Item
[A21] Primary biliary cirrhosis
boolean
C0008312 (UMLS CUI [1])
Primary sclerosing cholangitis
Item
[A22] Primary sclerosing cholangitis
boolean
C0008311 (UMLS CUI [1])
Autoimmune overlap syndrome
Item
[A23] Autoimmune overlap syndrome
boolean
C2702837 (UMLS CUI [1])
Hemochromatosis
Item
[A24] Hemochromatosis
boolean
C0018995 (UMLS CUI [1])
Alpha-1-antitrypsin deficiency
Item
[A25] Alpha-1-antitrypsin deficiency
boolean
C0221757 (UMLS CUI [1])
Wilson's disease
Item
[A26] Wilson's disease
boolean
C0019202 (UMLS CUI [1])
Liver: Veno-occlusive disease
Item
[A27] Veno-occlusive disease
boolean
C0019156 (UMLS CUI [1])
Budd-Chiari syndrome
Item
[A28] Budd-Chiari syndrome
boolean
C0856761 (UMLS CUI [1])
Liver Neoplasia
Item
[A29] Neoplasia
boolean
C1882062 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Other Final Diagnosis
Item
[A99] Other
boolean
C1546485 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Final Diagnosis specification
Item
Other, specify:
text
C1546485 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Liver Architecture
C0023884 (UMLS CUI-1)
C0935919 (UMLS CUI-2)
Item
5. Liver Architecture
text
C0935919 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Code List
5. Liver Architecture
CL Item
Normal (B1)
CL Item
Check all that apply (BBB)
Liver: Bridging fibrosis
Item
[B2] Bridging fibrosis
boolean
C0334160 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Diffuse fibrosis
Item
[B3] Diffuse fibrosis
boolean
C1265984 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver: Nodular regenerative hyperplasia
Item
[B4] Nodular regenerative hyperplasia
boolean
C0020510 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Congenital hepatic fibrosis
Item
[B5] Congenital hepatic fibrosis
boolean
C0009714 (UMLS CUI [1])
Cirrhosis
Item
[B6] Cirrhosis
boolean
C0023890 (UMLS CUI [1])
Centrilobular congestion
Item
[B7] Centrilobular congestion
boolean
C0267821 (UMLS CUI [1,1])
C0442080 (UMLS CUI [1,2])
Liver Endophlebitis
Item
[B8] Endophlebitis
boolean
C0014234 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver Veno-occlusive disease
Item
[B9] Veno-occlusive disease
boolean
C0019156 (UMLS CUI [1])
Canalicular cholestasis
Item
[B10] Canalicular cholestasis
boolean
C3150342 (UMLS CUI [1])
Liver Apoptosis
Item
[B11] Apoptosis
boolean
C0162638 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Focal (or spotty or mild) hepatocellular necrosis
Item
[B12] Focal (or spotty or mild) hepatocellular necrosis
boolean
C0267800 (UMLS CUI [1])
Interface hepatitis
Item
[B13] Interface hepatitis (periportal hepatitis or piecemeal necrosis)
boolean
C0333515 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver: Ischaemic necrosis
Item
[B14] Ischaemic necrosis
boolean
C3887513 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Centrolobular necrosis
Item
[B15] Centrolobular (Zone 3) necrosis
boolean
C3672032 (UMLS CUI [1])
Focal coagulative necrosis
Item
[B16] Focal coagulative necrosis
boolean
C1522058 (UMLS CUI [1,1])
C0205234 (UMLS CUI [1,2])
Centrolobular coagulative necrosis
Item
[B17] Centrolobular (Zone 3) coagulative necrosis
boolean
C1522058 (UMLS CUI [1,1])
C0682619 (UMLS CUI [1,2])
Bridging hepatocellular necrosis
Item
[B18] Bridging hepatocellular necrosis
boolean
C1855038 (UMLS CUI [1,1])
C0333511 (UMLS CUI [1,2])
Massive or panlobular hepatocellular necrosis
Item
[B19] Massive or panlobular hepatocellular necrosis
boolean
C1855038 (UMLS CUI [1,1])
C0442131 (UMLS CUI [1,2])
C0001364 (UMLS CUI [2])
Liver Dysplasia
Item
[B20] Dysplasia
boolean
C0334044 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Liver Neoplasia
Item
[B21] Neoplasia
boolean
C1882062 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
Other Liver Architecture
Item
[B99] Other
boolean
C0023884 (UMLS CUI [1,1])
C0935919 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Other Liver Architecture specification
Item
Other, specify:
text
C0935919 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C2348235 (UMLS CUI [1,4])
Item Group
Description of Liver Cells or Hepatocytes
C0227525 (UMLS CUI-1)
C0678257 (UMLS CUI-2)
Item
6. Description of Liver Cells or Hepatocytes
text
C0227525 (UMLS CUI [1,1])
C0678257 (UMLS CUI [1,2])
Code List
6. Description of Liver Cells or Hepatocytes
CL Item
Normal (C0)
CL Item
Check all that apply (CCC)
Ballooning Liver Cells or Hepatocytes
Item
[C1] Ballooning
boolean
C0333445 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Acidophilic Liver Cells or Hepatocytes
Item
[C2] Acidophilic
boolean
C0227525 (UMLS CUI [1,1])
C0333931 (UMLS CUI [1,2])
Pseudoxanthomatous Liver Cells or Hepatocytes
Item
[C3] Pseudoxanthomatous
boolean
C0227525 (UMLS CUI [1,1])
C3277905 (UMLS CUI [1,2])
Multinucleated giant hepatocytes
Item
[C4] Multinucleated giant hepatocytes
boolean
C3550474 (UMLS CUI [1,1])
C1850414 (UMLS CUI [1,2])
Other Liver Cells or Hepatocytes
Item
[C99] Other
boolean
C0227525 (UMLS CUI [1,1])
C0678257 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Other Liver Cells or Hepatocytes specification
Item
Other, specify:
text
C0227525 (UMLS CUI [1,1])
C0678257 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C2348235 (UMLS CUI [1,4])
Item Group
Liver Cell or Hepatocyte Inclusions or Vacuoles
C0227525 (UMLS CUI-1)
C1512693 (UMLS CUI-2)
C0042219 (UMLS CUI-3)
Item
7. Liver Cell or Hepatocyte Inclusions or Vacuoles
text
C0227525 (UMLS CUI [1,1])
C0042219 (UMLS CUI [1,2])
C0227525 (UMLS CUI [2,1])
C1512693 (UMLS CUI [2,2])
Code List
7. Liver Cell or Hepatocyte Inclusions or Vacuoles
CL Item
No inclusions (D0)
CL Item
Check all that apply (DDD)
Macrovesicular steatosis
Item
[D1] Macrovesicular steatosis
boolean
C1837256 (UMLS CUI [1])
Microvesicular steatosis
Item
D2] Microvesicular steatosis
boolean
C1850415 (UMLS CUI [1])
Bile accumulation
Item
[D3] Bile accumulation
boolean
C3686784 (UMLS CUI [1])
Diastase-resistant, PAS-positive cytoplasmic inclusions
Item
[D4] Diastase-resistant, PAS-positive cytoplasmic inclusions
boolean
C1856311 (UMLS CUI [1])
Alpha-1-antitrypsin inclusions
Item
[D5] Alpha-1-antitrypsin inclusions
boolean
C0002191 (UMLS CUI [1,1])
C1512693 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
Megamitochondria
Item
[D6] Megamitochondria
boolean
C0544931 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Mallory bodies
Item
[D7] Mallory bodies
boolean
C0333744 (UMLS CUI [1])
Ground Glass inclusions
Item
[D8] "Ground Glass" inclusions
boolean
C0598786 (UMLS CUI [1])
Hepatocyte Lipofuscin pigment
Item
[D9] Lipofuscin pigment
boolean
C0023789 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Hemosiderin granules
Item
[D10] Hemosiderin granules
boolean
C0019113 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Orcein-positive cytoplasmin granules
Item
[D11] Orcein-positive cytoplasmin granules
boolean
C0069596 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Protoporphyrin crystals
Item
[D12] Protoporphyrin crystals (birefringent under polarised light)
boolean
C0033733 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Uroporphyrin crystals
Item
[D13] Uroporphyrin crystals (red fluorescence under ultraviolet light)
boolean
C0042093 (UMLS CUI [1,1])
C0227525 (UMLS CUI [1,2])
Other Liver Cell or Hepatocyte Inclusions or Vacuoles
Item
[D99] Other
boolean
C0227525 (UMLS CUI [1,1])
C0042219 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0227525 (UMLS CUI [2,1])
C1512693 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
Other Liver Cell or Hepatocyte Inclusions or Vacuoles specification
Item
Other, specify:
text
C0227525 (UMLS CUI [1,1])
C0042219 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C0227525 (UMLS CUI [2,1])
C1512693 (UMLS CUI [2,2])
C0205394 (UMLS CUI [2,3])
C1521902 (UMLS CUI [3])
Item Group
Hepatocyte or Liver Cell Nuclear Abnormalities
C0227525 (UMLS CUI-1)
C1849376 (UMLS CUI-2)
Item
8. Hepatocyte or Liver Cell Nuclear Abnormalities
text
C0227525 (UMLS CUI [1,1])
C1849376 (UMLS CUI [1,2])
Code List
8. Hepatocyte or Liver Cell Nuclear Abnormalities
CL Item
None (E0)
CL Item
Check all that apply (EEE)
Hepatocellular mitosis
Item
[E1] Hepatocellular mitosis
boolean
C2697585 (UMLS CUI [1,1])
C0026255 (UMLS CUI [1,2])
Binucleated or multinucleated hepatocytes
Item
[E2] Binucleated or multinucleated hepatocytes
boolean
C0227525 (UMLS CUI [1,1])
C0333909 (UMLS CUI [1,2])
C4054455 (UMLS CUI [2])
CMV inclusion bodies
Item
[E3] CMV inclusion bodies
boolean
C0582172 (UMLS CUI [1,1])
C1366904 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
HSV inclusions
Item
[E4] HSV inclusions
boolean
C0319232 (UMLS CUI [1,1])
C1366904 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
Varicella inclusions
Item
[E5] Varicella inclusions
boolean
C0740380 (UMLS CUI [1,1])
C1366904 (UMLS CUI [1,2])
C0227525 (UMLS CUI [1,3])
Other Hepatocyte or Liver Cell Nuclear Abnormalities
Item
[E99] Other
boolean
C0227525 (UMLS CUI [1,1])
C1849376 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
Other Hepatocyte or Liver Cell Nuclear Abnormalities specification
Item
Other, specify:
text
C0227525 (UMLS CUI [1,1])
C1849376 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1521902 (UMLS CUI [1,4])
Item Group
Liver or Lobular Infiltrates
C0205417 (UMLS CUI-1)
C1400896 (UMLS CUI-2)
C1400896 (UMLS CUI-4)
Item
9. Liver or Lobular Infiltrates
text
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C1400896 (UMLS CUI [2])
Code List
9. Liver or Lobular Infiltrates
CL Item
None (F0)
CL Item
Check all that apply (FFF)
Liver or Lobular Infiltrates Eosinophils
Item
[F1] Eosinophils
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0014467 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0014467 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Lymphocytes
Item
[F2] Lymphocytes
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0024264 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0024264 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Plasma cells
Item
[F3] Plasma cells
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0032112 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0032112 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Neutrophils
Item
[F4] Neutrophils
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0027950 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0027950 (UMLS CUI [2,2])
Liver or Lobular Infiltrates Macrophages and proliferating Kupffer cells
Item
[F5] Macrophages and proliferating Kupffer cells
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0022801 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0022801 (UMLS CUI [2,2])
C1168262 (UMLS CUI [3])
Liver or Lobular Infiltrates Granulomas
Item
[F6] Granulomas
boolean
C0745754 (UMLS CUI [1,1])
C0205417 (UMLS CUI [1,2])
C0745754 (UMLS CUI [2])
Other Liver or Lobular Infiltrates
Item
[F99] Other
boolean
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
Other Liver or Lobular Infiltrates specification
Item
Other, specify:
text
C0205417 (UMLS CUI [1,1])
C1400896 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C1400896 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
C1521902 (UMLS CUI [3])
Item Group
Portal Tract Inflammation
C3854488 (UMLS CUI-1)
Item
10. Portal Tract Inflammation
text
C3854488 (UMLS CUI [1])
Code List
10. Portal Tract Inflammation
CL Item
None (G0)
CL Item
Check all that apply (GGG)
Portal Tract Inflammation Eosinophils
Item
[G1] Eosinophils
boolean
C0014467 (UMLS CUI [1,1])
C3854488 (UMLS CUI [1,2])
Portal Tract Inflammation Lymphoid aggregates and/or follicles
Item
[G2] Lymphoid aggregates and/or follicles
boolean
C3854488 (UMLS CUI [1,1])
C0229653 (UMLS CUI [1,2])
Portal Tract Inflammation Plasma cells
Item
[G3] Plasma cells
boolean
C3854488 (UMLS CUI [1,1])
C0032112 (UMLS CUI [1,2])
Portal Tract Inflammation Neutrophils
Item
[G4] Neutrophils
boolean
C3854488 (UMLS CUI [1,1])
C0027950 (UMLS CUI [1,2])
Portal Tract Inflammation Histocytes and macrophages
Item
[G5] Histocytes and macrophages
boolean
C3854488 (UMLS CUI [1,1])
C0024432 (UMLS CUI [1,2])
C3854488 (UMLS CUI [2,1])
C0019612 (UMLS CUI [2,2])
Other Portal Tract Inflammation
Item
[G99] Other
boolean
C3854488 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Portal Tract Inflammation specification
Item
Other, specify:
text
C3854488 (UMLS CUI [1,1])
C3845569 (UMLS CUI [1,2])
Item Group
Bile Ducts
C0005400 (UMLS CUI-1)
Item
11. Bile Ducts
text
C0005400 (UMLS CUI [1])
Code List
11. Bile Ducts
CL Item
Normal (H0)
CL Item
Check all that apply (HHH)
Proliferation of bile ducts
Item
[H1] Proliferation of bile ducts (bile ductular reaction)
boolean
C0005400 (UMLS CUI [1,1])
C0334094 (UMLS CUI [1,2])
Dilation, degeneration or disruption of portal bile ducts
Item
[H2] Dilation, degeneration or disruption of portal bile ducts
boolean
C0005400 (UMLS CUI [1,1])
C0011164 (UMLS CUI [1,2])
C1849767 (UMLS CUI [2])
C0005400 (UMLS CUI [3,1])
C0332453 (UMLS CUI [3,2])
Paucity of bile ducts
Item
[H3] Paucity of bile ducts
boolean
C4273160 (UMLS CUI [1])
Periductal fibrosis
Item
[H4] Periductal fibrosis
boolean
C0016059 (UMLS CUI [1,1])
C0005400 (UMLS CUI [1,2])
Bile ducts Other
Item
[H99] Other
boolean
C0205394 (UMLS CUI [1,1])
C0005400 (UMLS CUI [1,2])
Bile ducts Other specification
Item
Other, specify
text
C0205394 (UMLS CUI [1,1])
C0005400 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Portal Veins
C0032718 (UMLS CUI-1)
Item
12. Portal Veins
text
C0032718 (UMLS CUI [1])
Code List
12. Portal Veins
CL Item
Normal (I0)
CL Item
Check all that apply (III)
Pyelophlebitis
Item
[I1] Pyelophlebitis
boolean
C1405883 (UMLS CUI [1,1])
C0032718 (UMLS CUI [1,2])
Thrombosis, sclerosis or occlusion of portal vein
Item
[I2] Thrombosis, sclerosis or occlusion of portal vein
boolean
C0155773 (UMLS CUI [1])
C0400960 (UMLS CUI [2])
C0265029 (UMLS CUI [3])
Neoplastic invasion of portal vein
Item
[I3] Neoplastic invasion of portal vein
boolean
C1709160 (UMLS CUI [1,1])
C1510886 (UMLS CUI [1,2])
C0032718 (UMLS CUI [1,3])
Granulomatous compression of portal vein
Item
[I4] Granulomatous compression of portal vein
boolean
C0032718 (UMLS CUI [1,1])
C0439667 (UMLS CUI [1,2])
C0728907 (UMLS CUI [1,3])
Portal veins Other
Item
[I99] Other
boolean
C0032718 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Portal veins Other specification
Item
Other, specify:
text
C0032718 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Liver Infections
C1112211 (UMLS CUI-1)
Item
13. Liver Infections
text
C1112211 (UMLS CUI [1])
Code List
13. Liver Infections
CL Item
Normal (J0)
CL Item
Check all that apply (JJJ)
Liver: Leishmaniasis donovani
Item
[J1] Leishmaniasis donovani
boolean
C0023273 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Plasmodium falciparum
Item
[J2] Plasmodium falciparum
boolean
C0032150 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Toxoplasmosis
Item
[J3] Toxoplasmosis
boolean
C0040558 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Cryptococcus neoformans
Item
[J4] Cryptococcus neoformans
boolean
C0010416 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Histoplasma capsulatum
Item
[J5] Histoplasma capsulatum
boolean
C0319941 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Liver: Mycobacterium tuberculois
Item
[J6] Mycobacterium tuberculois
boolean
C0026926 (UMLS CUI [1,1])
C1112211 (UMLS CUI [1,2])
Other mycobacterial species
Item
[J7] Other mycobacterial species
boolean
C0205394 (UMLS CUI [1,1])
C0026918 (UMLS CUI [1,2])
C1112211 (UMLS CUI [1,3])
Other Liver Infections
Item
[J99] Other
boolean
C1112211 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Liver Infections specification
Item
Other, specify:
text
C1112211 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])
Item Group
Parasites or Ova
C0030498 (UMLS CUI-1)
C1267673 (UMLS CUI-2)
C0023884 (UMLS CUI-3)
Item
14. Parasites or Ova
text
C0030498 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0555117 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Code List
14. Parasites or Ova
CL Item
None (K0)
CL Item
Check all that apply (KKK)
Schistosome and/or ova
Item
[K1] Schistosome and/or ova
boolean
C4303012 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0036315 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Ascaris and/or ova
Item
[K2] Ascaris and/or ova
boolean
C3698183 (UMLS CUI [1,1])
C0023884 (UMLS CUI [1,2])
C0003954 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Toxocara and/or ova
Item
[K3] Toxocara and/or ova
boolean
C0040550 (UMLS CUI [1,1])
C1267673 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C0040550 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Echinococcus cysts
Item
[K4] Echinococcus cysts
boolean
C0013502 (UMLS CUI [1])
Hepatic capillariasis worms and/or ova
Item
[K5] Hepatic capillariasis worms and/or ova
boolean
C0006896 (UMLS CUI [1,1])
C1267673 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C0277202 (UMLS CUI [2,1])
C0023884 (UMLS CUI [2,2])
Other Parasites or Ova
Item
[K99] Other
boolean
C0030498 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C1267673 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
C0023884 (UMLS CUI [2,3])
Other Parasites or Ova specification
Item
Other, specify:
text
C0030498 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0023884 (UMLS CUI [1,3])
C1267673 (UMLS CUI [2,1])
C0205394 (UMLS CUI [2,2])
C0023884 (UMLS CUI [2,3])
C2348235 (UMLS CUI [3])
Item Group
15. Histologic Staining or Additional Studies Obtained
C0487602 (UMLS CUI-1)
C0430022 (UMLS CUI-2)
C0023884 (UMLS CUI-3)
Haematoxylin and eosin
Item
[L1] Haematoxylin and eosin (or H & E)
boolean
C0523207 (UMLS CUI [1])
Masson
Item
[L2] Masson
boolean
C1294297 (UMLS CUI [1])
Toluidine blue or Giemsa
Item
[L3] Toluidine blue or Giemsa
boolean
C0523203 (UMLS CUI [1])
C0017542 (UMLS CUI [2])
Prussian blue
Item
[L4] Prussian blue
boolean
C1294004 (UMLS CUI [1])
Periodic Acidic Schiff with or without diastase
Item
[L5] Periodic Acidic Schiff (PAS), with or without diastase
boolean
C0440048 (UMLS CUI [1,1])
C0002712 (UMLS CUI [1,2])
C0440048 (UMLS CUI [2,1])
C0332288 (UMLS CUI [2,2])
C0002712 (UMLS CUI [2,3])
Oil red O
Item
[L6] Oil red O
boolean
C1294000 (UMLS CUI [1])
Congo red
Item
[L7] Congo red
boolean
C0009742 (UMLS CUI [1])
Hall's stain
Item
[L8] Hall's stain
boolean
C1720394 (UMLS CUI [1])
Gridley's stain
Item
[L9] Gridley's stain
boolean
C1293978 (UMLS CUI [1])
Rhodanine
Item
[L10] Rhodanine (copper)
boolean
C0035486 (UMLS CUI [1,1])
C0009968 (UMLS CUI [1,2])
C0487602 (UMLS CUI [1,3])
Rubeanic acid
Item
[L11] Rubeanic acid (copper)
boolean
C0073680 (UMLS CUI [1,1])
C0009968 (UMLS CUI [1,2])
C0487602 (UMLS CUI [1,3])
Orcein, aldehyde fuchsin or Victoria blue
Item
[L12] Orcein, aldehyde fuchsin or Victoria blue
boolean
C1294001 (UMLS CUI [1])
C0491984 (UMLS CUI [2])
C0078232 (UMLS CUI [3,1])
C0487602 (UMLS CUI [3,2])
Electron microscopy
Item
[L13] Electron microscopy
boolean
C0026019 (UMLS CUI [1])
Hepatitis A immunostains positive
Item
[L14] Hepatitis A immunostains positive
boolean
C0560226 (UMLS CUI [1,1])
C3687908 (UMLS CUI [1,2])
Hepatitis B core antigen or hepatitis B surface antibody immunostains positive
Item
[L15] Hepatitis B core antigen or hepatitis B surface antibody immunostains positive
boolean
C0019166 (UMLS CUI [1,1])
C3687908 (UMLS CUI [1,2])
C0369334 (UMLS CUI [2,1])
C3687908 (UMLS CUI [2,2])
Hepatitis D immunostains
Item
[L16] Hepatitis D immunostains
boolean
C0011226 (UMLS CUI [1,1])
C3687908 (UMLS CUI [1,2])
Other immunostains
Item
[L17] Other immunostains
boolean
C3687908 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Histologic Staining or Additional Studies Obtained
Item
[L99] Other
boolean
C0487602 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Other Histologic Staining or Additional Studies Obtained specification
Item
Other, specify:
text
C0487602 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348235 (UMLS CUI [1,3])

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