ID

31731

Beschreibung

Effect of Endothelin-1 Receptor Blockade on Circulating Endothelial Microparticles Levels in Patients With Pulmonary Hypertension; ODM derived from: https://clinicaltrials.gov/show/NCT00675051

Link

https://clinicaltrials.gov/show/NCT00675051

Stichworte

Versionen (1)
  1. 23.09.18 23.09.18 -
Rechteinhaber

See clinicaltrials.gov

Hochgeladen am

23. September 2018

DOI

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Lizenz

Creative Commons BY 4.0
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Eligibility Pulmonary Hypertension NCT00675051

Englisch

Eligibility Pulmonary Hypertension NCT00675051

1 Formulare  
Inclusion Criteria
Beschreibung

Inclusion Criteria

Alias
UMLS CUI
C1512693
patient's + 18 years with suspected pre-capillary pulmonary hypertension
Beschreibung

Age | Precapillary pulmonary hypertension Suspected

Datentyp

boolean

Alias
UMLS CUI [1]
C0001779
UMLS CUI [2,1]
C3696954
UMLS CUI [2,2]
C0750491
prescribed endothelial - 1 receptor blocker
Beschreibung

Endothelin A Receptor Antagonists prescribed

Datentyp

boolean

Alias
UMLS CUI [1,1]
C1516869
UMLS CUI [1,2]
C0278329
Exclusion Criteria
Beschreibung

Exclusion Criteria

Alias
UMLS CUI
C0680251
currently taking endothelium-active vasodilator therapy.
Beschreibung

Vasodilator Agents Endothelium Active

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0042402
UMLS CUI [1,2]
C0014257
UMLS CUI [1,3]
C0205177
hemoglobin and / or hematocrit level blood the lower normal limit.
Beschreibung

Hemoglobin measurement Lower Limit of Normal | Hematocrit level Lower Limit of Normal

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0518015
UMLS CUI [1,2]
C1518030
UMLS CUI [2,1]
C0518014
UMLS CUI [2,2]
C1518030
left ventricle dysfunction (lvef <50%)
Beschreibung

Left ventricular cardiac dysfunction | LVEF

Datentyp

boolean

Alias
UMLS CUI [1]
C1997351
UMLS CUI [2]
C0428772
lv end-diastolic pressure > 15 mmhg)
Beschreibung

Left ventricular end-diastolic pressure measurement

Datentyp

boolean

Alias
UMLS CUI [1]
C1171395
recent history (<3 months) of pulmonary embolism
Beschreibung

Pulmonary Embolism

Datentyp

boolean

Alias
UMLS CUI [1]
C0034065
liver failure or abnormal liver function tests; aortic or mitral regurgitation or stenosis
Beschreibung

Liver Failure | Liver function tests abnormal | Aortic Regurgitation | Aortic Stenosis | Mitral Regurgitation | Mitral Stenosis

Datentyp

boolean

Alias
UMLS CUI [1]
C0085605
UMLS CUI [2]
C0151766
UMLS CUI [3]
C0003504
UMLS CUI [4]
C0003507
UMLS CUI [5]
C0026266
UMLS CUI [6]
C0026269
current medication with endothelin-1 receptor antagonist, prostacyclin analogues or type 5 phosphodiesterase inhibitors.
Beschreibung

Endothelin A Receptor Antagonists | Prostaglandin Analog | Phosphodiesterase 5 inhibitor

Datentyp

boolean

Alias
UMLS CUI [1]
C1516869
UMLS CUI [2]
C3536889
UMLS CUI [3]
C1318700
subjects with conditions known to be associated with an increase in circulating endothelial microparticle numers, such as chronic renal failure (creatinine clearance < 50 ml/min/m2) acute coronary syndromes and uncontrolled system hypertension.
Beschreibung

Condition Associated with Endothelial microparticle formation Increased | Kidney Failure, Chronic | Creatinine clearance measurement | Acute Coronary Syndrome | Uncontrolled hypertension

Datentyp

boolean

Alias
UMLS CUI [1,1]
C0348080
UMLS CUI [1,2]
C0332281
UMLS CUI [1,3]
C3156620
UMLS CUI [1,4]
C0205217
UMLS CUI [2]
C0022661
UMLS CUI [3]
C0373595
UMLS CUI [4]
C0948089
UMLS CUI [5]
C1868885
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Ähnliche Modelle

Eligibility Pulmonary Hypertension NCT00675051

1 Formulare
Name
Typ
Description | Question | Decode (Coded Value)
Datentyp
Alias
Item Group
C1512693 (UMLS CUI)
Age | Precapillary pulmonary hypertension Suspected
Item
patient's + 18 years with suspected pre-capillary pulmonary hypertension
boolean
C0001779 (UMLS CUI [1])
C3696954 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
Endothelin A Receptor Antagonists prescribed
Item
prescribed endothelial - 1 receptor blocker
boolean
C1516869 (UMLS CUI [1,1])
C0278329 (UMLS CUI [1,2])
Item Group
C0680251 (UMLS CUI)
Vasodilator Agents Endothelium Active
Item
currently taking endothelium-active vasodilator therapy.
boolean
C0042402 (UMLS CUI [1,1])
C0014257 (UMLS CUI [1,2])
C0205177 (UMLS CUI [1,3])
Hemoglobin measurement Lower Limit of Normal | Hematocrit level Lower Limit of Normal
Item
hemoglobin and / or hematocrit level blood the lower normal limit.
boolean
C0518015 (UMLS CUI [1,1])
C1518030 (UMLS CUI [1,2])
C0518014 (UMLS CUI [2,1])
C1518030 (UMLS CUI [2,2])
Left ventricular cardiac dysfunction | LVEF
Item
left ventricle dysfunction (lvef <50%)
boolean
C1997351 (UMLS CUI [1])
C0428772 (UMLS CUI [2])
Left ventricular end-diastolic pressure measurement
Item
lv end-diastolic pressure > 15 mmhg)
boolean
C1171395 (UMLS CUI [1])
Pulmonary Embolism
Item
recent history (<3 months) of pulmonary embolism
boolean
C0034065 (UMLS CUI [1])
Liver Failure | Liver function tests abnormal | Aortic Regurgitation | Aortic Stenosis | Mitral Regurgitation | Mitral Stenosis
Item
liver failure or abnormal liver function tests; aortic or mitral regurgitation or stenosis
boolean
C0085605 (UMLS CUI [1])
C0151766 (UMLS CUI [2])
C0003504 (UMLS CUI [3])
C0003507 (UMLS CUI [4])
C0026266 (UMLS CUI [5])
C0026269 (UMLS CUI [6])
Endothelin A Receptor Antagonists | Prostaglandin Analog | Phosphodiesterase 5 inhibitor
Item
current medication with endothelin-1 receptor antagonist, prostacyclin analogues or type 5 phosphodiesterase inhibitors.
boolean
C1516869 (UMLS CUI [1])
C3536889 (UMLS CUI [2])
C1318700 (UMLS CUI [3])
Condition Associated with Endothelial microparticle formation Increased | Kidney Failure, Chronic | Creatinine clearance measurement | Acute Coronary Syndrome | Uncontrolled hypertension
Item
subjects with conditions known to be associated with an increase in circulating endothelial microparticle numers, such as chronic renal failure (creatinine clearance < 50 ml/min/m2) acute coronary syndromes and uncontrolled system hypertension.
boolean
C0348080 (UMLS CUI [1,1])
C0332281 (UMLS CUI [1,2])
C3156620 (UMLS CUI [1,3])
C0205217 (UMLS CUI [1,4])
C0022661 (UMLS CUI [2])
C0373595 (UMLS CUI [3])
C0948089 (UMLS CUI [4])
C1868885 (UMLS CUI [5])
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