ID

31725

Descripción

Modulating Effects of Lisinopril on Sildenafil Activity in Pulmonary Arterial Hypertension(PAH)( MELISSA); ODM derived from: https://clinicaltrials.gov/show/NCT01181284

Link

https://clinicaltrials.gov/show/NCT01181284

Palabras clave

Versiones (1)
  1. 23/9/18 23/9/18 -
Titular de derechos de autor

See clinicaltrials.gov

Subido en

23 de septiembre de 2018

DOI

Para solicitar uno, por favor iniciar sesión.

Licencia

Creative Commons BY 4.0
Comentarios del modelo :

Puede comentar sobre el modelo de datos aquí. A través de las burbujas de diálogo en los grupos de elementos y elementos, puede agregar comentarios específicos.

Volver a los comentarios del modelo
Comentarios de grupo de elementos para :

Comentarios del elemento para :

Para descargar modelos de datos, debe haber iniciado sesión. Por favor iniciar sesión o Registrate gratis.

Eligibility Pulmonary Arterial Hypertension NCT01181284

Inglés

Eligibility Pulmonary Arterial Hypertension NCT01181284

1 formularios  
Inclusion Criteria
Descripción

Inclusion Criteria

Alias
UMLS CUI
C1512693
age 18-75
Descripción

Age

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0001779
world health organization (who) group i pah with prior documentation of peripheral vascular resistance (pvr) > 3 wu and wedge(pcw) 16 or less.
Descripción

Pulmonary arterial hypertension WHO classification | Peripheral Vascular Resistance Wood units Quantity | Pulmonary Capillary Wedge Pressure

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C2973725
UMLS CUI [1,2]
C4267671
UMLS CUI [2,1]
C1258192
UMLS CUI [2,2]
C0439525
UMLS CUI [2,3]
C1265611
UMLS CUI [3]
C0086879
who functional class i-iii
Descripción

WHO classification

Tipo de datos

boolean

Alias
UMLS CUI [1]
C4267671
6 minute walk distance 150-575 meters
Descripción

6-Minute Walk Test Meter Quantity

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0430515
UMLS CUI [1,2]
C0475209
UMLS CUI [1,3]
C1265611
women of child bearing potential must have a negative pregnancy test and be using effective contraception
Descripción

Childbearing Potential Pregnancy test negative | Childbearing Potential Contraceptive methods

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C3831118
UMLS CUI [1,2]
C0427780
UMLS CUI [2,1]
C3831118
UMLS CUI [2,2]
C0700589
receiving therapy with phosphodiesterase-5 inhibitor for pah (sildenafil or tadalafil) for at least 3 months and with stable dose for at least 30 days
Descripción

Phosphodiesterase 5 inhibitor Dose Stable Pulmonary arterial hypertension | sildenafil | tadalafil

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1318700
UMLS CUI [1,2]
C0178602
UMLS CUI [1,3]
C0205360
UMLS CUI [1,4]
C2973725
UMLS CUI [2]
C0529793
UMLS CUI [3]
C1176316
if already receiving therapy with endothelin receptor antagonists must have been on therapy for at least 3 months and on stable dose for at least 30 days
Descripción

Endothelin receptor antagonist Dose Stable

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C1134681
UMLS CUI [1,2]
C0178602
UMLS CUI [1,3]
C0205360
Exclusion Criteria
Descripción

Exclusion Criteria

Alias
UMLS CUI
C0680251
allergy or intolerance to captopril or other angiotensin converting enzyme inhibitors
Descripción

Captopril allergy | Intolerance to Captopril | Angiotensin-converting-enzyme inhibitor allergy | Intolerance to Angiotensin-Converting Enzyme Inhibitors

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0571940
UMLS CUI [2,1]
C1744706
UMLS CUI [2,2]
C0006938
UMLS CUI [3]
C0571939
UMLS CUI [4,1]
C1744706
UMLS CUI [4,2]
C0003015
systemic systolic blood pressure less than 100 mm hg
Descripción

Systolic Pressure Systemic

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0871470
UMLS CUI [1,2]
C0205373
therapy with prostanoids (iloprost, treprostinil, epoprostenol) within preceding 3 months
Descripción

Prostaglandins | Iloprost | Treprostinil | Epoprostenol

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0033554
UMLS CUI [2]
C0079594
UMLS CUI [3]
C1145760
UMLS CUI [4]
C0033567
pregnant or breast feeding
Descripción

Pregnancy | Breast Feeding

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0032961
UMLS CUI [2]
C0006147
creatinine > 2.0 mg/dl
Descripción

Creatinine measurement, serum

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0201976
potassium > 5.0 meq/dl
Descripción

Serum potassium measurement

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0302353
unable to provide informed consent
Descripción

Informed Consent Unable

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0021430
UMLS CUI [1,2]
C1299582
tlc or vc <60% predicted
Descripción

Percent Predicted Total Lung Capacity | Percentage of predicted vital capacity

Tipo de datos

boolean

Alias
UMLS CUI [1]
C3828589
UMLS CUI [2]
C2919340
untreated obstructive sleep apnea
Descripción

Obstructive Sleep Apnea untreated

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0520679
UMLS CUI [1,2]
C0332155
lvef < 40%
Descripción

Left ventricular ejection fraction

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0428772
hb < 10 mg/dl
Descripción

Hemoglobin measurement

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0518015
Volver a la parte superior de la página

Similar models

Eligibility Pulmonary Arterial Hypertension NCT01181284

1 formularios
Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
C1512693 (UMLS CUI)
Age
Item
age 18-75
boolean
C0001779 (UMLS CUI [1])
Pulmonary arterial hypertension WHO classification | Peripheral Vascular Resistance Wood units Quantity | Pulmonary Capillary Wedge Pressure
Item
world health organization (who) group i pah with prior documentation of peripheral vascular resistance (pvr) > 3 wu and wedge(pcw) 16 or less.
boolean
C2973725 (UMLS CUI [1,1])
C4267671 (UMLS CUI [1,2])
C1258192 (UMLS CUI [2,1])
C0439525 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C0086879 (UMLS CUI [3])
WHO classification
Item
who functional class i-iii
boolean
C4267671 (UMLS CUI [1])
6-Minute Walk Test Meter Quantity
Item
6 minute walk distance 150-575 meters
boolean
C0430515 (UMLS CUI [1,1])
C0475209 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
Childbearing Potential Pregnancy test negative | Childbearing Potential Contraceptive methods
Item
women of child bearing potential must have a negative pregnancy test and be using effective contraception
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Phosphodiesterase 5 inhibitor Dose Stable Pulmonary arterial hypertension | sildenafil | tadalafil
Item
receiving therapy with phosphodiesterase-5 inhibitor for pah (sildenafil or tadalafil) for at least 3 months and with stable dose for at least 30 days
boolean
C1318700 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C2973725 (UMLS CUI [1,4])
C0529793 (UMLS CUI [2])
C1176316 (UMLS CUI [3])
Endothelin receptor antagonist Dose Stable
Item
if already receiving therapy with endothelin receptor antagonists must have been on therapy for at least 3 months and on stable dose for at least 30 days
boolean
C1134681 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
Item Group
C0680251 (UMLS CUI)
Captopril allergy | Intolerance to Captopril | Angiotensin-converting-enzyme inhibitor allergy | Intolerance to Angiotensin-Converting Enzyme Inhibitors
Item
allergy or intolerance to captopril or other angiotensin converting enzyme inhibitors
boolean
C0571940 (UMLS CUI [1])
C1744706 (UMLS CUI [2,1])
C0006938 (UMLS CUI [2,2])
C0571939 (UMLS CUI [3])
C1744706 (UMLS CUI [4,1])
C0003015 (UMLS CUI [4,2])
Systolic Pressure Systemic
Item
systemic systolic blood pressure less than 100 mm hg
boolean
C0871470 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
Prostaglandins | Iloprost | Treprostinil | Epoprostenol
Item
therapy with prostanoids (iloprost, treprostinil, epoprostenol) within preceding 3 months
boolean
C0033554 (UMLS CUI [1])
C0079594 (UMLS CUI [2])
C1145760 (UMLS CUI [3])
C0033567 (UMLS CUI [4])
Pregnancy | Breast Feeding
Item
pregnant or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Creatinine measurement, serum
Item
creatinine > 2.0 mg/dl
boolean
C0201976 (UMLS CUI [1])
Serum potassium measurement
Item
potassium > 5.0 meq/dl
boolean
C0302353 (UMLS CUI [1])
Informed Consent Unable
Item
unable to provide informed consent
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Percent Predicted Total Lung Capacity | Percentage of predicted vital capacity
Item
tlc or vc <60% predicted
boolean
C3828589 (UMLS CUI [1])
C2919340 (UMLS CUI [2])
Obstructive Sleep Apnea untreated
Item
untreated obstructive sleep apnea
boolean
C0520679 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
Left ventricular ejection fraction
Item
lvef < 40%
boolean
C0428772 (UMLS CUI [1])
Hemoglobin measurement
Item
hb < 10 mg/dl
boolean
C0518015 (UMLS CUI [1])
Volver a la parte superior de la página 

Contacto

Utilice este formulario para comentarios, preguntas y sugerencias.

Los campos marcados con * son obligatorios.

Ayuda

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial