ID

31534

Beskrivning

Methotrexate-based Chemo-immunotherapy Followed by Maintenance Therapy for Patients > 65 Years With Central Nervous System (CNS)-Lymphoma; ODM derived from: https://clinicaltrials.gov/show/NCT00989352

Länk

https://clinicaltrials.gov/show/NCT00989352

Nyckelord

Versioner (2)
  1. 2018-09-01 2018-09-01 -
  2. 2018-09-01 2018-09-01 -
Rättsinnehavare

See clinicaltrials.gov

Uppladdad den

1 september 2018

DOI

För en begäran logga in.

Licens

Creative Commons BY 4.0
Modellkommentarer :

Här kan du kommentera modellen. Med hjälp av pratbubblor i Item-grupperna och Item kan du lägga in specifika kommentarer.

Tillbaka till modellkommentarer
Itemgroup-kommentar för :

Item-kommentar för :

Du måste vara inloggad för att kunna ladda ner formulär. Var vänlig logga in eller registrera dig utan kostnad.

Eligibility Primary Non Hodgkin Lymphoma of the Central Nervous System NCT00989352

Engelsk

Eligibility Primary Non Hodgkin Lymphoma of the Central Nervous System NCT00989352

1 Formulär  
Inclusion Criteria
Beskrivning

Inclusion Criteria

Alias
UMLS CUI
C1512693
first diagnosis of pcnsl, histologically confirmed
Beskrivning

Primary central nervous system lymphoma

Datatyp

boolean

Alias
UMLS CUI [1]
C0280803
age > 65 years
Beskrivning

Age

Datatyp

boolean

Alias
UMLS CUI [1]
C0001779
written signed and dated informed consent of the legal representative and - if possible - of the patient
Beskrivning

Informed Consent Patient Representative | Informed Consent

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0021430
UMLS CUI [1,2]
C0030701
UMLS CUI [2]
C0021430
Exclusion Criteria
Beskrivning

Exclusion Criteria

Alias
UMLS CUI
C0680251
manifestations of further lymphoma outside the cns
Beskrivning

Manifestation of Lymphoma Additional | Exception Central Nervous System

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1280464
UMLS CUI [1,2]
C0024299
UMLS CUI [1,3]
C1524062
UMLS CUI [2,1]
C1705847
UMLS CUI [2,2]
C3714787
sero-positive for hiv
Beskrivning

HIV Seropositivity

Datatyp

boolean

Alias
UMLS CUI [1]
C0019699
severe pulmonary, cardiac, hepatic, renal impairment
Beskrivning

Pulmonary function impairment Severe | Impairment cardiac Severe | Hepatic impairment Severe | Renal Insufficiency Severe

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0858943
UMLS CUI [1,2]
C0205082
UMLS CUI [2,1]
C0221099
UMLS CUI [2,2]
C0018787
UMLS CUI [2,3]
C0205082
UMLS CUI [3,1]
C0948807
UMLS CUI [3,2]
C0205082
UMLS CUI [4,1]
C1565489
UMLS CUI [4,2]
C0205082
uncontrolled infection
Beskrivning

Communicable Disease Uncontrolled

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0009450
UMLS CUI [1,2]
C0205318
neutrophil count < 1.500/µl, platelet count < 100.000/µl
Beskrivning

Neutrophil count | Platelet Count measurement

Datatyp

boolean

Alias
UMLS CUI [1]
C0200633
UMLS CUI [2]
C0032181
pulmonary disease with ivc < 55%, dlco < 40%
Beskrivning

Lung disease | Inspiratory Vital Capacity Test | DLCO

Datatyp

boolean

Alias
UMLS CUI [1]
C0024115
UMLS CUI [2]
C4085887
UMLS CUI [3]
C1516251
cardiac ejection fraction < 50%, uncontrolled malign arrhythmia
Beskrivning

Cardiac ejection fraction | Cardiac Arrhythmia Malignant Uncontrolled

Datatyp

boolean

Alias
UMLS CUI [1]
C0232174
UMLS CUI [2,1]
C0003811
UMLS CUI [2,2]
C0205282
UMLS CUI [2,3]
C0205318
creatinine > 1,5 mg% or creatinine-clearance < 50ml/min
Beskrivning

Creatinine measurement, serum | Creatinine clearance measurement

Datatyp

boolean

Alias
UMLS CUI [1]
C0201976
UMLS CUI [2]
C0373595
bilirubin > 2mg/dl
Beskrivning

Serum total bilirubin measurement

Datatyp

boolean

Alias
UMLS CUI [1]
C1278039
ascites or pleural effusion (> 500ml)
Beskrivning

Ascites | Pleural effusion

Datatyp

boolean

Alias
UMLS CUI [1]
C0003962
UMLS CUI [2]
C0032227
known hypersensitivity against methotrexate, lomustine, procarbazine, rituximab, leukovorin, or dexamethasone
Beskrivning

Methotrexate allergy | Lomustine allergy | Procarbazine allergy | Hypersensitivity Rituximab | Hypersensitivity Leucovorin | Dexamethasone allergy

Datatyp

boolean

Alias
UMLS CUI [1]
C0570693
UMLS CUI [2]
C0570678
UMLS CUI [3]
C0570704
UMLS CUI [4,1]
C0020517
UMLS CUI [4,2]
C0393022
UMLS CUI [5,1]
C0020517
UMLS CUI [5,2]
C0023413
UMLS CUI [6]
C0571611
participation in another clinical trial within the last 30 days prior to the begin or parallel to this study
Beskrivning

Study Subject Participation Status

Datatyp

boolean

Alias
UMLS CUI [1]
C2348568
known or current drug or alcohol abuse
Beskrivning

Substance Use Disorders

Datatyp

boolean

Alias
UMLS CUI [1]
C0038586
Tillbaka till toppen

Similar models

Eligibility Primary Non Hodgkin Lymphoma of the Central Nervous System NCT00989352

1 Formulär
Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
C1512693 (UMLS CUI)
Primary central nervous system lymphoma
Item
first diagnosis of pcnsl, histologically confirmed
boolean
C0280803 (UMLS CUI [1])
Age
Item
age > 65 years
boolean
C0001779 (UMLS CUI [1])
Informed Consent Patient Representative | Informed Consent
Item
written signed and dated informed consent of the legal representative and - if possible - of the patient
boolean
C0021430 (UMLS CUI [1,1])
C0030701 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2])
Item Group
C0680251 (UMLS CUI)
Manifestation of Lymphoma Additional | Exception Central Nervous System
Item
manifestations of further lymphoma outside the cns
boolean
C1280464 (UMLS CUI [1,1])
C0024299 (UMLS CUI [1,2])
C1524062 (UMLS CUI [1,3])
C1705847 (UMLS CUI [2,1])
C3714787 (UMLS CUI [2,2])
HIV Seropositivity
Item
sero-positive for hiv
boolean
C0019699 (UMLS CUI [1])
Pulmonary function impairment Severe | Impairment cardiac Severe | Hepatic impairment Severe | Renal Insufficiency Severe
Item
severe pulmonary, cardiac, hepatic, renal impairment
boolean
C0858943 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0221099 (UMLS CUI [2,1])
C0018787 (UMLS CUI [2,2])
C0205082 (UMLS CUI [2,3])
C0948807 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C1565489 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
Communicable Disease Uncontrolled
Item
uncontrolled infection
boolean
C0009450 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Neutrophil count | Platelet Count measurement
Item
neutrophil count < 1.500/µl, platelet count < 100.000/µl
boolean
C0200633 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
Lung disease | Inspiratory Vital Capacity Test | DLCO
Item
pulmonary disease with ivc < 55%, dlco < 40%
boolean
C0024115 (UMLS CUI [1])
C4085887 (UMLS CUI [2])
C1516251 (UMLS CUI [3])
Cardiac ejection fraction | Cardiac Arrhythmia Malignant Uncontrolled
Item
cardiac ejection fraction < 50%, uncontrolled malign arrhythmia
boolean
C0232174 (UMLS CUI [1])
C0003811 (UMLS CUI [2,1])
C0205282 (UMLS CUI [2,2])
C0205318 (UMLS CUI [2,3])
Creatinine measurement, serum | Creatinine clearance measurement
Item
creatinine > 1,5 mg% or creatinine-clearance < 50ml/min
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
Serum total bilirubin measurement
Item
bilirubin > 2mg/dl
boolean
C1278039 (UMLS CUI [1])
Ascites | Pleural effusion
Item
ascites or pleural effusion (> 500ml)
boolean
C0003962 (UMLS CUI [1])
C0032227 (UMLS CUI [2])
Methotrexate allergy | Lomustine allergy | Procarbazine allergy | Hypersensitivity Rituximab | Hypersensitivity Leucovorin | Dexamethasone allergy
Item
known hypersensitivity against methotrexate, lomustine, procarbazine, rituximab, leukovorin, or dexamethasone
boolean
C0570693 (UMLS CUI [1])
C0570678 (UMLS CUI [2])
C0570704 (UMLS CUI [3])
C0020517 (UMLS CUI [4,1])
C0393022 (UMLS CUI [4,2])
C0020517 (UMLS CUI [5,1])
C0023413 (UMLS CUI [5,2])
C0571611 (UMLS CUI [6])
Study Subject Participation Status
Item
participation in another clinical trial within the last 30 days prior to the begin or parallel to this study
boolean
C2348568 (UMLS CUI [1])
Substance Use Disorders
Item
known or current drug or alcohol abuse
boolean
C0038586 (UMLS CUI [1])
Tillbaka till toppen 

Kontakt

Använd detta formulär för feedback, frågor och förslag på förbättringar.

Fält markerade med * är obligatoriska.

Hjälp

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial