ID

31448

Descrizione

Expiratory Muscle Training for Persons With Neurodegenerative Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00856518

collegamento

https://clinicaltrials.gov/show/NCT00856518

Keywords

versioni (1)
  1. 22/08/18 22/08/18 -
Titolare del copyright

See clinicaltrials.gov

Caricato su

22 agosto 2018

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY 4.0
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Eligibility Parkinson's Disease NCT00856518

Inglese

Eligibility Parkinson's Disease NCT00856518

1 moduli  
Inclusion Criteria
Descrizione

Inclusion Criteria

Alias
UMLS CUI
C1512693
multiple sclerosis participants
Descrizione

Multiple Sclerosis Participant

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0026769
UMLS CUI [1,2]
C0681850
diagnosis of primary, secondary, or relapsing-remitting ms by a neurologist. over 85% of the patient populations that come from the study sites demonstrate relapsing-remitting ms with an average relapse frequency of once every 3 years.
Descrizione

Multiple Sclerosis Primary | Multiple Sclerosis Secondary | Multiple Sclerosis, Relapsing-Remitting | Relapsing-Remitting Multiple Sclerosis Average Relapse Frequency

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0026769
UMLS CUI [1,2]
C0205225
UMLS CUI [2,1]
C0026769
UMLS CUI [2,2]
C0175668
UMLS CUI [3]
C0751967
UMLS CUI [4,1]
C0751967
UMLS CUI [4,2]
C1510992
UMLS CUI [4,3]
C0035020
UMLS CUI [4,4]
C0439603
parkinson's disease participants
Descrizione

Parkinson Disease Participant

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0030567
UMLS CUI [1,2]
C0681850
hoehn & yahr, stage ii and iii as indicated by certified movement disorders neurologist
Descrizione

Hoehn and Yahr Stage

Tipo di dati

boolean

Alias
UMLS CUI [1]
C3639483
all participants
Descrizione

Participant All

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0681850
UMLS CUI [1,2]
C0444868
between 35 and 80 years of age
Descrizione

Age

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0001779
non-smoking or no smoking within the previous five years
Descrizione

Non-smoker | Tobacco use Absent Duration

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0337672
UMLS CUI [2,1]
C0543414
UMLS CUI [2,2]
C0332197
UMLS CUI [2,3]
C0449238
no history of head and neck cancer, asthma or copd, untreated hypertension
Descrizione

Malignant Head and Neck Neoplasm Absent | Asthma Absent | Chronic Obstructive Airway Disease Absent | Hypertension untreated Absent

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0278996
UMLS CUI [1,2]
C0332197
UMLS CUI [2,1]
C0004096
UMLS CUI [2,2]
C0332197
UMLS CUI [3,1]
C0024117
UMLS CUI [3,2]
C0332197
UMLS CUI [4,1]
C0745134
UMLS CUI [4,2]
C0332197
sufficient facial muscle strength so as to achieve and maintain adequate lip closure around a circular mouthpiece
Descrizione

Muscle Strength Facial Sufficient

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0517349
UMLS CUI [1,2]
C0015450
UMLS CUI [1,3]
C0205410
cognition within normal limits as determined by the: mini mental status exam (mmse; 1975no neurological (other than ms or pd) condition which adversely affects respiratory muscle or gas exchange system
Descrizione

Cognition normal Mini-mental state examination | Absence Neurologic conditions Negative Respiratory Muscles | Absence Neurologic conditions Negative Gas exchange status | Exception Multiple Sclerosis | Exception Parkinson Disease

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C2712133
UMLS CUI [1,2]
C0451306
UMLS CUI [2,1]
C0332197
UMLS CUI [2,2]
C4489311
UMLS CUI [2,3]
C1513916
UMLS CUI [2,4]
C0035231
UMLS CUI [3,1]
C0332197
UMLS CUI [3,2]
C4489311
UMLS CUI [3,3]
C1513916
UMLS CUI [3,4]
C0518226
UMLS CUI [4,1]
C1705847
UMLS CUI [4,2]
C0026769
UMLS CUI [5,1]
C1705847
UMLS CUI [5,2]
C0030567
reduced mep's compared to published normative data for age and sex
Descrizione

Motor Evoked Potentials Reduced

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0282617
UMLS CUI [1,2]
C0392756
reduced expiratory peak flow rates (6-8 l/s for young to middle age adults and 3.6 l/s for 65 and older) during voluntary cough production for age and sex (bolser, personal communication; smith-hammond & goldstein, 2006)
Descrizione

Decreased peak expiratory flow rate | Young Adult | Middle Aged | Elderly

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0520843
UMLS CUI [2]
C0238598
UMLS CUI [3]
C0205847
UMLS CUI [4]
C0001792
participant report of symptoms related to swallow impairment
Descrizione

Symptoms Relationship Impaired ability to swallow

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1457887
UMLS CUI [1,2]
C0439849
UMLS CUI [1,3]
C4061143
Exclusion Criteria
Descrizione

Exclusion Criteria

Alias
UMLS CUI
C0680251
dbs copd asthma smoking or smoking within preceding 5 years
Descrizione

Deep Brain Stimulation | Chronic Obstructive Airway Disease | Asthma | Tobacco use

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0394162
UMLS CUI [2]
C0024117
UMLS CUI [3]
C0004096
UMLS CUI [4]
C0543414
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Similar models

Eligibility Parkinson's Disease NCT00856518

1 moduli
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
C1512693 (UMLS CUI)
Multiple Sclerosis Participant
Item
multiple sclerosis participants
boolean
C0026769 (UMLS CUI [1,1])
C0681850 (UMLS CUI [1,2])
Multiple Sclerosis Primary | Multiple Sclerosis Secondary | Multiple Sclerosis, Relapsing-Remitting | Relapsing-Remitting Multiple Sclerosis Average Relapse Frequency
Item
diagnosis of primary, secondary, or relapsing-remitting ms by a neurologist. over 85% of the patient populations that come from the study sites demonstrate relapsing-remitting ms with an average relapse frequency of once every 3 years.
boolean
C0026769 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
C0026769 (UMLS CUI [2,1])
C0175668 (UMLS CUI [2,2])
C0751967 (UMLS CUI [3])
C0751967 (UMLS CUI [4,1])
C1510992 (UMLS CUI [4,2])
C0035020 (UMLS CUI [4,3])
C0439603 (UMLS CUI [4,4])
Parkinson Disease Participant
Item
parkinson's disease participants
boolean
C0030567 (UMLS CUI [1,1])
C0681850 (UMLS CUI [1,2])
Hoehn and Yahr Stage
Item
hoehn & yahr, stage ii and iii as indicated by certified movement disorders neurologist
boolean
C3639483 (UMLS CUI [1])
Participant All
Item
all participants
boolean
C0681850 (UMLS CUI [1,1])
C0444868 (UMLS CUI [1,2])
Age
Item
between 35 and 80 years of age
boolean
C0001779 (UMLS CUI [1])
Non-smoker | Tobacco use Absent Duration
Item
non-smoking or no smoking within the previous five years
boolean
C0337672 (UMLS CUI [1])
C0543414 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0449238 (UMLS CUI [2,3])
Malignant Head and Neck Neoplasm Absent | Asthma Absent | Chronic Obstructive Airway Disease Absent | Hypertension untreated Absent
Item
no history of head and neck cancer, asthma or copd, untreated hypertension
boolean
C0278996 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0004096 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0024117 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
C0745134 (UMLS CUI [4,1])
C0332197 (UMLS CUI [4,2])
Muscle Strength Facial Sufficient
Item
sufficient facial muscle strength so as to achieve and maintain adequate lip closure around a circular mouthpiece
boolean
C0517349 (UMLS CUI [1,1])
C0015450 (UMLS CUI [1,2])
C0205410 (UMLS CUI [1,3])
Cognition normal Mini-mental state examination | Absence Neurologic conditions Negative Respiratory Muscles | Absence Neurologic conditions Negative Gas exchange status | Exception Multiple Sclerosis | Exception Parkinson Disease
Item
cognition within normal limits as determined by the: mini mental status exam (mmse; 1975no neurological (other than ms or pd) condition which adversely affects respiratory muscle or gas exchange system
boolean
C2712133 (UMLS CUI [1,1])
C0451306 (UMLS CUI [1,2])
C0332197 (UMLS CUI [2,1])
C4489311 (UMLS CUI [2,2])
C1513916 (UMLS CUI [2,3])
C0035231 (UMLS CUI [2,4])
C0332197 (UMLS CUI [3,1])
C4489311 (UMLS CUI [3,2])
C1513916 (UMLS CUI [3,3])
C0518226 (UMLS CUI [3,4])
C1705847 (UMLS CUI [4,1])
C0026769 (UMLS CUI [4,2])
C1705847 (UMLS CUI [5,1])
C0030567 (UMLS CUI [5,2])
Motor Evoked Potentials Reduced
Item
reduced mep's compared to published normative data for age and sex
boolean
C0282617 (UMLS CUI [1,1])
C0392756 (UMLS CUI [1,2])
Decreased peak expiratory flow rate | Young Adult | Middle Aged | Elderly
Item
reduced expiratory peak flow rates (6-8 l/s for young to middle age adults and 3.6 l/s for 65 and older) during voluntary cough production for age and sex (bolser, personal communication; smith-hammond & goldstein, 2006)
boolean
C0520843 (UMLS CUI [1])
C0238598 (UMLS CUI [2])
C0205847 (UMLS CUI [3])
C0001792 (UMLS CUI [4])
Symptoms Relationship Impaired ability to swallow
Item
participant report of symptoms related to swallow impairment
boolean
C1457887 (UMLS CUI [1,1])
C0439849 (UMLS CUI [1,2])
C4061143 (UMLS CUI [1,3])
Item Group
C0680251 (UMLS CUI)
Deep Brain Stimulation | Chronic Obstructive Airway Disease | Asthma | Tobacco use
Item
dbs copd asthma smoking or smoking within preceding 5 years
boolean
C0394162 (UMLS CUI [1])
C0024117 (UMLS CUI [2])
C0004096 (UMLS CUI [3])
C0543414 (UMLS CUI [4])
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