ID

29889

Description

The Efficacy of Spironolactone in Patients With Resistant Hypertension; ODM derived from: https://clinicaltrials.gov/show/NCT00430794

Link

https://clinicaltrials.gov/show/NCT00430794

Keywords

Versions (1)
  1. 4/25/18 4/25/18 -
Copyright Holder

See clinicaltrials.gov

Uploaded on

April 25, 2018

DOI

To request one please log in.

License

Creative Commons BY 4.0
Model comments :

You can comment on the data model here. Via the speech bubbles at the itemgroups and items you can add comments to those specificially.

Back to model comments
Itemgroup comments for :

Item comments for :

In order to download data models you must be logged in. Please log in or register for free.

Eligibility Hypertension NCT00430794

English

Eligibility Hypertension NCT00430794

1 forms  
Inclusion Criteria
Description

Inclusion Criteria

Alias
UMLS CUI
C1512693
aged over 18 years
Description

Age

Data type

boolean

Alias
UMLS CUI [1]
C0001779
hypertension (essential or secondary) managed in sheffield hypertension clinic or general practice or both.
Description

Essential Hypertension | Secondary hypertension

Data type

boolean

Alias
UMLS CUI [1]
C0085580
UMLS CUI [2]
C0155616
blood pressures not adequately controlled (systolic blood pressure (sbp) >140 mmhg and/or diastolic blood pressure (dbp) >85 mmhg in clinic and on ambulatory blood pressure monitoring) despite treatment with the maximum tolerated dose of three antihypertensive agents.
Description

Blood Pressure Poorly controlled | Systolic Pressure | Diastolic blood pressure | Antihypertensive Agents Quantity Maximum Tolerated Dose

Data type

boolean

Alias
UMLS CUI [1,1]
C0005823
UMLS CUI [1,2]
C3853134
UMLS CUI [2]
C0871470
UMLS CUI [3]
C0428883
UMLS CUI [4,1]
C0003364
UMLS CUI [4,2]
C1265611
UMLS CUI [4,3]
C0752079
additional antihypertensive treatment deemed appropriate by the patients' doctor.
Description

Antihypertensive therapy Additional Appropriate

Data type

boolean

Alias
UMLS CUI [1,1]
C0585941
UMLS CUI [1,2]
C1524062
UMLS CUI [1,3]
C1548787
patients' current antihypertensive treatment includes a thiazide diuretic and at least one of a beta-blocker, angiotensin converting enzyme inhibitor or angiotensin ii receptor antagonist.
Description

Antihypertensive therapy | Thiazide Diuretic | Adrenergic beta-1 Receptor Antagonists Quantity | Angiotensin-Converting Enzyme Inhibitors Quantity | Angiotensin II receptor antagonist Quantity

Data type

boolean

Alias
UMLS CUI [1]
C0585941
UMLS CUI [2]
C0012802
UMLS CUI [3,1]
C0304516
UMLS CUI [3,2]
C1265611
UMLS CUI [4,1]
C0003015
UMLS CUI [4,2]
C1265611
UMLS CUI [5,1]
C0521942
UMLS CUI [5,2]
C1265611
Exclusion Criteria
Description

Exclusion Criteria

Alias
UMLS CUI
C0680251
definite indication or contraindication for spironolactone
Description

Indication Spironolactone | Medical contraindication Spironolactone

Data type

boolean

Alias
UMLS CUI [1,1]
C3146298
UMLS CUI [1,2]
C0037982
UMLS CUI [2,1]
C1301624
UMLS CUI [2,2]
C0037982
known conn's syndrome (definite indication for spironolactone)
Description

Conn Syndrome | Indication Spironolactone

Data type

boolean

Alias
UMLS CUI [1]
C1384514
UMLS CUI [2,1]
C3146298
UMLS CUI [2,2]
C0037982
heart failure nyha class iii or iv (definite indication for spironolactone)
Description

Heart failure New York Heart Association Classification | Indication Spironolactone

Data type

boolean

Alias
UMLS CUI [1,1]
C0018801
UMLS CUI [1,2]
C1275491
UMLS CUI [2,1]
C3146298
UMLS CUI [2,2]
C0037982
known hepatic failure or significant cirrhosis
Description

Liver Failure | Liver Cirrhosis

Data type

boolean

Alias
UMLS CUI [1]
C0085605
UMLS CUI [2]
C0023890
known pregnancy or women planning pregnancy
Description

Pregnancy | Pregnancy, Planned

Data type

boolean

Alias
UMLS CUI [1]
C0032961
UMLS CUI [2]
C0032992
women of child bearing potential not using adequate contraceptive methods
Description

Childbearing Potential Contraceptive methods Absent

Data type

boolean

Alias
UMLS CUI [1,1]
C3831118
UMLS CUI [1,2]
C0700589
UMLS CUI [1,3]
C0332197
serum creatinine > 221µmol/l
Description

Creatinine measurement, serum

Data type

boolean

Alias
UMLS CUI [1]
C0201976
serum potassium > 5.0mmol/l
Description

Serum potassium measurement

Data type

boolean

Alias
UMLS CUI [1]
C0302353
clinic blood pressure or daytime ambulatory blood pressure >240/120
Description

Blood pressure determination Clinic | Blood pressure ambulatory Daytime

Data type

boolean

Alias
UMLS CUI [1,1]
C0005824
UMLS CUI [1,2]
C0442592
UMLS CUI [2,1]
C0855316
UMLS CUI [2,2]
C0332169
Back to the top of the page

Similar models

Eligibility Hypertension NCT00430794

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
C1512693 (UMLS CUI)
Age
Item
aged over 18 years
boolean
C0001779 (UMLS CUI [1])
Essential Hypertension | Secondary hypertension
Item
hypertension (essential or secondary) managed in sheffield hypertension clinic or general practice or both.
boolean
C0085580 (UMLS CUI [1])
C0155616 (UMLS CUI [2])
Blood Pressure Poorly controlled | Systolic Pressure | Diastolic blood pressure | Antihypertensive Agents Quantity Maximum Tolerated Dose
Item
blood pressures not adequately controlled (systolic blood pressure (sbp) >140 mmhg and/or diastolic blood pressure (dbp) >85 mmhg in clinic and on ambulatory blood pressure monitoring) despite treatment with the maximum tolerated dose of three antihypertensive agents.
boolean
C0005823 (UMLS CUI [1,1])
C3853134 (UMLS CUI [1,2])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
C0003364 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
C0752079 (UMLS CUI [4,3])
Antihypertensive therapy Additional Appropriate
Item
additional antihypertensive treatment deemed appropriate by the patients' doctor.
boolean
C0585941 (UMLS CUI [1,1])
C1524062 (UMLS CUI [1,2])
C1548787 (UMLS CUI [1,3])
Antihypertensive therapy | Thiazide Diuretic | Adrenergic beta-1 Receptor Antagonists Quantity | Angiotensin-Converting Enzyme Inhibitors Quantity | Angiotensin II receptor antagonist Quantity
Item
patients' current antihypertensive treatment includes a thiazide diuretic and at least one of a beta-blocker, angiotensin converting enzyme inhibitor or angiotensin ii receptor antagonist.
boolean
C0585941 (UMLS CUI [1])
C0012802 (UMLS CUI [2])
C0304516 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0003015 (UMLS CUI [4,1])
C1265611 (UMLS CUI [4,2])
C0521942 (UMLS CUI [5,1])
C1265611 (UMLS CUI [5,2])
Item Group
C0680251 (UMLS CUI)
Indication Spironolactone | Medical contraindication Spironolactone
Item
definite indication or contraindication for spironolactone
boolean
C3146298 (UMLS CUI [1,1])
C0037982 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0037982 (UMLS CUI [2,2])
Conn Syndrome | Indication Spironolactone
Item
known conn's syndrome (definite indication for spironolactone)
boolean
C1384514 (UMLS CUI [1])
C3146298 (UMLS CUI [2,1])
C0037982 (UMLS CUI [2,2])
Heart failure New York Heart Association Classification | Indication Spironolactone
Item
heart failure nyha class iii or iv (definite indication for spironolactone)
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C3146298 (UMLS CUI [2,1])
C0037982 (UMLS CUI [2,2])
Liver Failure | Liver Cirrhosis
Item
known hepatic failure or significant cirrhosis
boolean
C0085605 (UMLS CUI [1])
C0023890 (UMLS CUI [2])
Pregnancy | Pregnancy, Planned
Item
known pregnancy or women planning pregnancy
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Childbearing Potential Contraceptive methods Absent
Item
women of child bearing potential not using adequate contraceptive methods
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
Creatinine measurement, serum
Item
serum creatinine > 221µmol/l
boolean
C0201976 (UMLS CUI [1])
Serum potassium measurement
Item
serum potassium > 5.0mmol/l
boolean
C0302353 (UMLS CUI [1])
Blood pressure determination Clinic | Blood pressure ambulatory Daytime
Item
clinic blood pressure or daytime ambulatory blood pressure >240/120
boolean
C0005824 (UMLS CUI [1,1])
C0442592 (UMLS CUI [1,2])
C0855316 (UMLS CUI [2,1])
C0332169 (UMLS CUI [2,2])
Back to the top of the page 

Contact

Please use this form for feedback, questions and suggestions for improvements.

Fields marked with * are required.

Help

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial