ID

16782

Descrizione

Attitudes Towards Prophylactic Colectomy in Hereditary Non-polyposis Colorectal Cancer (HNPCC) Patients; ODM derived from: https://clinicaltrials.gov/show/NCT00582452

collegamento

https://clinicaltrials.gov/show/NCT00582452

Keywords

versioni (2)
  1. 07/08/16 07/08/16 -
  2. 07/08/16 07/08/16 -
Caricato su

7 agosto 2016

DOI

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Licenza

Creative Commons BY 4.0
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Eligibility Colorectal Cancer NCT00582452

Inglese

Eligibility Colorectal Cancer NCT00582452

1 moduli  
Inclusion Criteria
Descrizione

Inclusion Criteria

Alias
UMLS CUI
C1512693
are from a family that has a known mismatch repair mutation; or
Descrizione

Family member Mismatch Repair Mutation

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0086282
UMLS CUI [1,2]
C1155661
UMLS CUI [1,3]
C0026882
meet amsterdam i or amsterdam ii criteria that spell out the family and personal cancer history characteristics associated with hnpcc
Descrizione

Family history of cancer Associated with Hereditary Nonpolyposis Colorectal Neoplasms | Malignant Neoplasms Associated with Hereditary Nonpolyposis Colorectal Neoplasms

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0260515
UMLS CUI [1,2]
C0332281
UMLS CUI [1,3]
C0009405
UMLS CUI [2,1]
C0006826
UMLS CUI [2,2]
C0332281
UMLS CUI [2,3]
C0009405
are considered at sufficiently high risk by their crc specialty physician that prophylactic colectomy may be presented as an option (excluding fap).
Descrizione

Colorectal Carcinoma High risk | Colectomy Prophylactic | Adenomatous Polyposis Coli

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0009402
UMLS CUI [1,2]
C0332167
UMLS CUI [2,1]
C0009274
UMLS CUI [2,2]
C0199176
UMLS CUI [3]
C0032580
amsterdam i criteria
Descrizione

Amsterdam Criteria I

Tipo di dati

boolean

Alias
UMLS CUI [1]
C1706801
1. at least three relatives with a colorectal cancer and the following criteria:
Descrizione

Colorectal Carcinoma Relative Quantity

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0009402
UMLS CUI [1,2]
C0080103
UMLS CUI [1,3]
C1265611
one should be a first degree relative of the other two
Descrizione

First Degree Relative Quantity

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1517194
UMLS CUI [1,2]
C1265611
at least two successive generations should be affected
Descrizione

Involvement Generations succession Quantity

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1314939
UMLS CUI [1,2]
C0079411
UMLS CUI [1,3]
C0242538
UMLS CUI [1,4]
C1265611
at least one colorectal cancer should be diagnosed before the age of 50
Descrizione

Colorectal Carcinoma | Age

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0009402
UMLS CUI [2]
C0001779
familial adenomatous polyposis (fap) should be excluded in the colorectal cancer case(s), if any
Descrizione

Adenomatous Polyposis Coli | Colorectal Carcinoma

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0032580
UMLS CUI [2]
C0009402
amsterdam ii criteria (also known as revised amsterdam criteria
Descrizione

Amsterdam Criteria II

Tipo di dati

boolean

Alias
UMLS CUI [1]
C1879699
2. at least three relatives with an hnpcc-associated cancer (colorectal cancer, cancer of the endometrium, small bowel, ureter, or renal pelvis) *:
Descrizione

Malignant Neoplasms Associated with Hereditary Nonpolyposis Colorectal Neoplasms Relative Quantity | Colorectal Carcinoma | Malignant neoplasm of endometrium | Malignant tumor of small intestine | Malignant neoplasm of ureter | Malignant tumor of renal pelvis

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0006826
UMLS CUI [1,2]
C0332281
UMLS CUI [1,3]
C0009405
UMLS CUI [1,4]
C0080103
UMLS CUI [1,5]
C1265611
UMLS CUI [2]
C0009402
UMLS CUI [3]
C0007103
UMLS CUI [4]
C0153425
UMLS CUI [5]
C0153619
UMLS CUI [6]
C0153618
one should be a first degree relative of the other two
Descrizione

First Degree Relative Quantity

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1517194
UMLS CUI [1,2]
C1265611
at least two successive generations should be affected
Descrizione

Involvement Generations succession Quantity

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1314939
UMLS CUI [1,2]
C0079411
UMLS CUI [1,3]
C0242538
UMLS CUI [1,4]
C1265611
at least one relative should be diagnosed before age 50
Descrizione

Diagnosis Relative Quantity | Age

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0011900
UMLS CUI [1,2]
C0080103
UMLS CUI [1,3]
C1265611
UMLS CUI [2]
C0001779
fap should be excluded in the colorectal cancer case(s), if any *note: ovarian cancer will also be considered an hnpccassociated cancer as per lynch et al (nejm 2003)
Descrizione

Adenomatous Polyposis Coli | Colorectal Carcinoma | Ovarian Carcinoma | Malignant Neoplasms Associated with Hereditary Nonpolyposis Colorectal Neoplasms

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0032580
UMLS CUI [2]
C0009402
UMLS CUI [3]
C0029925
UMLS CUI [4,1]
C0006826
UMLS CUI [4,2]
C0332281
UMLS CUI [4,3]
C0009405
Exclusion Criteria
Descrizione

Exclusion Criteria

Alias
UMLS CUI
C0680251
non-english speaking
Descrizione

Able to speak English Language

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0564215
UMLS CUI [1,2]
C0376245
under the age of 18
Descrizione

Age

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0001779
are unable to give meaningful informed consent due to physical, psychiatric or cognitive disability
Descrizione

Comorbidity Informed Consent Limited

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0009488
UMLS CUI [1,2]
C0021430
UMLS CUI [1,3]
C0439801
are from a family affected by fap
Descrizione

Adenomatous Polyposis Coli Family member Affected

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0032580
UMLS CUI [1,2]
C0086282
UMLS CUI [1,3]
C0392760
have already undergone subtotal colectomy or total proctocolectomy
Descrizione

Partial resection of colon | Total Proctocolectomy

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0149750
UMLS CUI [2]
C0842176
are in active treatment and/or less than six months post-surgery for cancer.
Descrizione

cancer treatment | cancer surgery Postoperative Period

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0920425
UMLS CUI [2,1]
C0920424
UMLS CUI [2,2]
C0032790
have undergone genetic counseling and testing for hnpcc at mskcc
Descrizione

Genetic Counseling Hereditary Nonpolyposis Colorectal Neoplasms | Testing Hereditary Nonpolyposis Colorectal Neoplasms

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0017382
UMLS CUI [1,2]
C0009405
UMLS CUI [2,1]
C0039593
UMLS CUI [2,2]
C0009405
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Similar models

Eligibility Colorectal Cancer NCT00582452

1 moduli
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
C1512693 (UMLS CUI)
Family member Mismatch Repair Mutation
Item
are from a family that has a known mismatch repair mutation; or
boolean
C0086282 (UMLS CUI [1,1])
C1155661 (UMLS CUI [1,2])
C0026882 (UMLS CUI [1,3])
Family history of cancer Associated with Hereditary Nonpolyposis Colorectal Neoplasms | Malignant Neoplasms Associated with Hereditary Nonpolyposis Colorectal Neoplasms
Item
meet amsterdam i or amsterdam ii criteria that spell out the family and personal cancer history characteristics associated with hnpcc
boolean
C0260515 (UMLS CUI [1,1])
C0332281 (UMLS CUI [1,2])
C0009405 (UMLS CUI [1,3])
C0006826 (UMLS CUI [2,1])
C0332281 (UMLS CUI [2,2])
C0009405 (UMLS CUI [2,3])
Colorectal Carcinoma High risk | Colectomy Prophylactic | Adenomatous Polyposis Coli
Item
are considered at sufficiently high risk by their crc specialty physician that prophylactic colectomy may be presented as an option (excluding fap).
boolean
C0009402 (UMLS CUI [1,1])
C0332167 (UMLS CUI [1,2])
C0009274 (UMLS CUI [2,1])
C0199176 (UMLS CUI [2,2])
C0032580 (UMLS CUI [3])
Amsterdam Criteria I
Item
amsterdam i criteria
boolean
C1706801 (UMLS CUI [1])
Colorectal Carcinoma Relative Quantity
Item
1. at least three relatives with a colorectal cancer and the following criteria:
boolean
C0009402 (UMLS CUI [1,1])
C0080103 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
First Degree Relative Quantity
Item
one should be a first degree relative of the other two
boolean
C1517194 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Involvement Generations succession Quantity
Item
at least two successive generations should be affected
boolean
C1314939 (UMLS CUI [1,1])
C0079411 (UMLS CUI [1,2])
C0242538 (UMLS CUI [1,3])
C1265611 (UMLS CUI [1,4])
Colorectal Carcinoma | Age
Item
at least one colorectal cancer should be diagnosed before the age of 50
boolean
C0009402 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Adenomatous Polyposis Coli | Colorectal Carcinoma
Item
familial adenomatous polyposis (fap) should be excluded in the colorectal cancer case(s), if any
boolean
C0032580 (UMLS CUI [1])
C0009402 (UMLS CUI [2])
Amsterdam Criteria II
Item
amsterdam ii criteria (also known as revised amsterdam criteria
boolean
C1879699 (UMLS CUI [1])
Malignant Neoplasms Associated with Hereditary Nonpolyposis Colorectal Neoplasms Relative Quantity | Colorectal Carcinoma | Malignant neoplasm of endometrium | Malignant tumor of small intestine | Malignant neoplasm of ureter | Malignant tumor of renal pelvis
Item
2. at least three relatives with an hnpcc-associated cancer (colorectal cancer, cancer of the endometrium, small bowel, ureter, or renal pelvis) *:
boolean
C0006826 (UMLS CUI [1,1])
C0332281 (UMLS CUI [1,2])
C0009405 (UMLS CUI [1,3])
C0080103 (UMLS CUI [1,4])
C1265611 (UMLS CUI [1,5])
C0009402 (UMLS CUI [2])
C0007103 (UMLS CUI [3])
C0153425 (UMLS CUI [4])
C0153619 (UMLS CUI [5])
C0153618 (UMLS CUI [6])
First Degree Relative Quantity
Item
one should be a first degree relative of the other two
boolean
C1517194 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Involvement Generations succession Quantity
Item
at least two successive generations should be affected
boolean
C1314939 (UMLS CUI [1,1])
C0079411 (UMLS CUI [1,2])
C0242538 (UMLS CUI [1,3])
C1265611 (UMLS CUI [1,4])
Diagnosis Relative Quantity | Age
Item
at least one relative should be diagnosed before age 50
boolean
C0011900 (UMLS CUI [1,1])
C0080103 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0001779 (UMLS CUI [2])
Adenomatous Polyposis Coli | Colorectal Carcinoma | Ovarian Carcinoma | Malignant Neoplasms Associated with Hereditary Nonpolyposis Colorectal Neoplasms
Item
fap should be excluded in the colorectal cancer case(s), if any *note: ovarian cancer will also be considered an hnpccassociated cancer as per lynch et al (nejm 2003)
boolean
C0032580 (UMLS CUI [1])
C0009402 (UMLS CUI [2])
C0029925 (UMLS CUI [3])
C0006826 (UMLS CUI [4,1])
C0332281 (UMLS CUI [4,2])
C0009405 (UMLS CUI [4,3])
Item Group
C0680251 (UMLS CUI)
Able to speak English Language
Item
non-english speaking
boolean
C0564215 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
Age
Item
under the age of 18
boolean
C0001779 (UMLS CUI [1])
Comorbidity Informed Consent Limited
Item
are unable to give meaningful informed consent due to physical, psychiatric or cognitive disability
boolean
C0009488 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
Adenomatous Polyposis Coli Family member Affected
Item
are from a family affected by fap
boolean
C0032580 (UMLS CUI [1,1])
C0086282 (UMLS CUI [1,2])
C0392760 (UMLS CUI [1,3])
Partial resection of colon | Total Proctocolectomy
Item
have already undergone subtotal colectomy or total proctocolectomy
boolean
C0149750 (UMLS CUI [1])
C0842176 (UMLS CUI [2])
cancer treatment | cancer surgery Postoperative Period
Item
are in active treatment and/or less than six months post-surgery for cancer.
boolean
C0920425 (UMLS CUI [1])
C0920424 (UMLS CUI [2,1])
C0032790 (UMLS CUI [2,2])
Genetic Counseling Hereditary Nonpolyposis Colorectal Neoplasms | Testing Hereditary Nonpolyposis Colorectal Neoplasms
Item
have undergone genetic counseling and testing for hnpcc at mskcc
boolean
C0017382 (UMLS CUI [1,1])
C0009405 (UMLS CUI [1,2])
C0039593 (UMLS CUI [2,1])
C0009405 (UMLS CUI [2,2])
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